09/17/2010 07:06 pm ET | Updated May 25, 2011

Human Mattress Dominoes Guinness World Record BROKEN With Anderson Cooper & Kelly Ripa (VIDEO)

They said it couldn't be done, but the new Guinness World Record for the largest number of human mattress dominoes has been set.

On Friday's "Live! With Regis And Kelly," 380 people strapped to mattresses toppled each other, and flattened the previous record of 256 dominoes.

On the flight deck of the Intrepid Sea Air and Space Museum, Kelly Ripa was the first human domino to fall and Anderson Cooper was the last. In between, there were 378 people screaming as they went down.

WATCH the spectacular fall below: