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This Could Be The Key To Not Getting Sick From The Flu

Sick From Flu

The Huffington Post   First Posted: 08/31/11 01:44 PM ET Updated: 11/15/11 12:11 AM ET

You know those enviable people who seem like they never, ever get the flu? Even though they're exposed to the virus, they just don't get sick from it.

Now, new research reveals that it may not because the virus doesn't infect these people -- rather, their genes keep them from developing symptoms of the flu, and they can still be contagious and pass the virus on to others.

"Many people might conclude that if you are exposed to a virus and you don’t get sick, it’s because the virus didn’t stick or it was so weak, it just passed right through your system and your system didn’t notice. That’s not a correct notion," study researcher Alfred Hero, a professor at the University of Michigan, told MSNBC.

Hero and a team of Duke University researchers inoculated 17 people with the H3N2/Wisconsin strain of flu virus, and drew blood samples from these volunteers every six to eight hours. The researchers then used those blood samples to look at their genes to see if any of those associated with immunity were active.

After about five-and-a-half days, nine of the people came down with symptoms of the flu, but blood tests revealed that all 17 people were actually infected with the flu and that their bodies were making flu antibodies, according to the PLoS Genetics study.

MyHealthNewsDaily explained:

The symptom-free volunteers showed activity in genes performing antioxidant and anti-inflammatory functions, but their bodies' acute inflammatory responses were not active, said Alfred Hero, a co-author of the paper. Meanwhile, blood samples from the sick volunteers showed different, or even opposite, gene activity, Hero said.

Even though the number of people involved in the study was small, the quantity of blood samples gathered -- 267 -- and genes examined -- 22,000 -- was the largest done on the human immune response, the scientists explained.

Researchers also said that the discovery could help them to detect the flu early, since flu-sufferers developed a "genetic signature," signaling inflammation 36 hours before the worst of the flu symptoms set on, the Daily Mail reported. This would give people a "running start" to take preventive measures to stave off the worst flu symptoms, they said.

Symptoms of the flu include having a fever over 102 degrees Fahrenheit, feeling nauseous and fatigued, having muscle aches, chills, stuffy nose, headache and cough, and having a loss of appetite, according to the American Academy of Family Physicians.

To stop mild symptoms from becoming worse, the AAFP recommends getting rest, avoiding secondhand smoke, drinking lots of fluids to loosen mucus and gargling with warm salt water to soothe sore throats. For severe flu, a doctor can also prescribe antiviral medicine that can be inhaled, swallowed as a pill or taken as a syrup.

Aside from genes, there are other things you can do that can decrease your risk of getting sick. Some of these include remaining active and exercising, which increases circulation and thereby white blood cells that eat up germs, as well as getting enough sleep to restore the immune system, according to WebMD.

In addition, simply getting older could make you immune to certain strains of flu, Wired reported. Because an older person has been exposed to -- and possibly even vaccinated against -- many past strains of flu, their bodies may already have antibodies to more current strains that are similar to those past strains, according to Wired.

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You know those enviable people who seem like they never, ever get the flu? Even though they're exposed to the virus, they just don't get sick from it. Now, new research reveals that it may not bec...
You know those enviable people who seem like they never, ever get the flu? Even though they're exposed to the virus, they just don't get sick from it. Now, new research reveals that it may not bec...
 
 
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09:53 PM on 09/03/2011
My office has air blowing threw it ALL the time, each room has its OWN goal to either freeze us out or sweat us up. My point is WE ARENT allowed to open windows when she should be able too because " We'll break the system"
So breathing the building's AIR is LIKE breathing in a co workers cough, or cold.
06:40 PM on 09/01/2011
Hate to burst a bubble here. 67 years old, had the flu once in my life (I figured that was
enough for me) but get colds about every 4-5-6 years because my body needs to
regenerate immunity. Oh, and I've smoked since about 16 or 17 years old and I don't
partake in the herding to the annual flu shot.

I believe in good health, I expect good health. It's my right. And it's really that simple.
But, for those of you who believe in illness, by all means, get your shots, take your
medicine and visit your doctor frequently during hunting season. Strike that. Visit your
doctor frequently during "flu season". Oh, and in case you forget, they will announce
each year on television when the "flue season" starts, so you can get it early.
The power of suggestion.
12:39 PM on 09/01/2011
Wash your hands like an OCD person before and during flu season. Air kiss. People touch their faces every few mins and sometimes they don't wash hands after pooping. Eeeew! Or other things. A lady with pink eye was shaking hands at a school event and then excused herself bc her pink eye was bothering HER. We held our hands steady and washed them right away, but before I could, someone grabbed my hand. I felt so awful but didn't offer up the pink eye - the lady had just left. Wash hands, warm water and soap, keep your hands away from your eyes and mouth and nose. And teach your kids the same. Best way to prevent - aside from staying strong, eating well and exercising moderately.
10:46 AM on 09/01/2011
Last Febuary I was off from work for a week, I never left my house in that time except to go to my doctor. With in two days after, I had the flu.
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10:08 AM on 09/01/2011
Washing your hands with soap and warm water frequently is another way of avoiding the Flu.
10:05 AM on 09/01/2011
I've never had the real flu. I get every other respiratory bug out there, but the not the high fever, send-you-to-bed-for-a-week flu. Some years I get a flu shot, other years I just haven't bothered. I don't know if I have an immunity or I've just been lucky.
A friend of mine is a carrier for viruses. When she was kid she never got sick, but passed on all sorts of things to her brother-mumps, measles, etc.
09:44 AM on 09/01/2011
Wow , a real "Hero"
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palinsnuts
09:14 AM on 09/01/2011
Stay out of doctors office.
09:08 AM on 09/01/2011
I am 30 years old and I haven't had the flu since I was 8 or 9. I've also lived in NYC and Chicago, taking mass transit everyday, so statistically I had to have been exposed to the virus over and over again. I always knew it was my genes that prevented me from getting sick.
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btflash
08:46 AM on 09/01/2011
or maybe dont leave your home.......
05:46 AM on 09/01/2011
Silly me, I thought the answer was going to be get the flu vaccine or something equally sensible. Instead we're advised that we should have the right set of genes! Well, I'll get right on to that folks!
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Rafael Perez
05:33 AM on 09/01/2011
or you can eat healthy, drink healthy and live healthy and REDUCE your chances of getting sick. Assuming you're one of the many that easily get sick.
lovelybunchofcoconuts
It's nice, to be nice, to the nice
02:10 AM on 09/01/2011
Wasn't there some research not too long ago that said that we need to get colds in order to keep our immune systems strong? If your body doesn't keep responding to new strains you might get wiped out by a 10th or 100th generation mutation somewhere down the line. That's why I don't take extra special precautions. I hate having colds but basically they are a free vaccination, as far as I can tell.
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ConfuciusSay-
Aglets: their purpose is sinister.
12:40 AM on 09/01/2011
I get colds and such frequently- it's an occupational hazard at a medical office. One reason might be the heavy exercise regimen I follow: on any given day of exposure, I'm going to be exhausted at some point. After an especially heavy leg day last Friday I spent the next 2 days in bed with high fever and a stupor, and a gritty tracheitis. Lost 5 pounds over that weekend, and had to wonder if the outcome wouldn't have been different if I hadn't moved 20000 pounds...
09:37 AM on 09/01/2011
That is really the point in the article. In theory, I too, should always be sick since I'm constantly exposed, via my job, to all kinds of nasty stuff. But, I never am. NEVER. I've been exposed to rotovirus, H1N1, parainfluinza, etc. and I simply don't get it. I did have RSV two Christmas' in a row, though. That seems to speak to a very strong immune system and the question is really whether or not that is due to one's genetic makeup or not. In theory, if I had the specific "better immune gene" and you didn't but we were both exposed all the time to the same stuff, you'd have symptoms but I wouldn't, even though we both test +.
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12:37 AM on 09/01/2011
Getting older, yeah baby. Dead people do not catch flu.