Appearing on "Dr. Phil" for the second time in two days, George Anthony said he blamed his daughter, Casey Anthony, for the death of his two-year-old granddaughter, Caylee.
"Yeah, I blame my daughter for Caylee not being here today," George Anthony told Dr. Phil McGraw. "I lost Caylee three years ago and I believe I lost Casey at the same time. I believe that. She is responsible."
Casey Anthony was acquitted of killing Caylee in July. She was convicted on four lesser charges of lying to police and was released days after the trial ended. She is currently in Florida, serving a year of probation stemming from an unrelated 2010 conviction on check fraud charges.
George and Cindy Anthony have dramatically different points of view about their daughter's level of involvement in their Caylee's death.
Cindy Anthony said on the show that she does not know what happened on June 16, 2008 -- the day her daughter's attorneys claim Caylee drowned in the family swimming pool.
"I don't know, but something happened that day that forever changed [Casey's] behavior," she said. "I buy the part that Caylee drowned but I don't buy the circumstances surrounding the drowning."
George Anthony had a different point of view.
"I believe something else happened to her. ... I believe Casey or someone else she was with possibly gave too much to Caylee. She fell asleep and didn't wake up," he said.
When McGraw asked, "Too much what?" Anthony replied, "Possibly some kind of drug or something like that."
The drugs would have allowed Casey Anthony to "go out and have a good time. To be with friends," George Anthony said. His wife was visibly surprised by his response.
"This is the first time that I've heard this out of his mouth," Cindy Anthony said. She added: "I don't buy that for a moment. I'm sorry. We disagree about this. ... I'm really kind of shocked to hear that today."
George Anthony also said he suspects his daughter was present when Caylee was buried in the woods near their house and said that she "probably had some help."
Despite the difference in opinion, Cindy Anthony said she was not angry with her husband.
"If that's how he feels and he is finally getting that out in the open, then I think that's a good thing for him because he's held so much in," she said.
Casey Anthony Trial (ARTICLE CONTINUES BELOW)
Cindy Anthony had many potential excuses for her daughter's bizarre behavior, but did say she believed there is "something seriously wrong with ... her thought processes."
But, in regard to the verdict that set her daughter free, Cindy Anthony did not mince words.
"I believe that justice for Caylee was when her mother walked," she said. "I believe that with all my heart because I know the love that those two had and I know that Caylee's soul would never have rested. ... I believe it was an accident and until someone can prove differently that is what I believe."