According to Reuters, one of the victims -- in Cuilapa, Santa Rosa -- died in a landslide triggered by the earthquake. It is not yet clear how the other two reported fatalities occurred.
The U.S. Geological Survey (USGS) reports that a quake with a magnitude of 5.8 hit at 12:34:00 p.m. local time, or 2:34 p.m. EDT. Weaker earthquakes -- both measuring a magnitude of 4.8 -- struck about a half hour before and about 45 minutes after the larger tremor.
Local media also reported that a wall fell on several houses, trapping a family. It was not clear if there were more casualties.
Public buildings were evacuated in the area and school classes canceled, authorities said.
At least 53 people were killed when an earthquake struck in the Indian state of Sikkim on the India-Nepal border on Sunday.
UPDATE 6:08 p.m. EDT
UPDATE 6:31 p.m. EDT
The Associated Press reports four earthquakes rocked Guatemala today.
This is a developing story. Check back for updates.