Is Alzheimer's Disease Transmissible?

Could Alzheimer's disease be infectious?

Possibly, in a similar way as prion diseases like mad cow disease, according to a new study in mice.

The new findings suggest that "some of the sporadic Alzheimer's cases may arise from an infectious process, which occurs with other neurological diseases such as mad cow and its human form, Creutzfeldt-Jakob disease," said study researcher Claudio Soto, Ph.D., a neurology professor at The University of Texas Medical School at Houston, said in a statement. However, Sotos' study was just done in mice, and much more research is needed before the results can carry over into humans.

The study was published in the journal Molecular Psychiatry.

Researchers took brain tissue from a human with Alzheimer's disease and injected it into the brains of mice, and found that they went on to develop plaques and changes in the brain that are indicative of Alzheimer's. Researchers also injected brain tissue from a human without Alzheimer's into mice, and saw that they didn't develop any signs of the disease.

Soto said the inner workings of both Alzheimer's and prion diseases are similar -- they both involve a normal protein that becomes deformed and can then touch upon other normal proteins, making them into bad ones. Those proteins are what form plaques and tangles in the brain, that are believed to contribute to Alzheimer's disease.

Now, researchers are seeing if it's possible for transmission of Alzheimer's to occur under natural exposure, rather than in an artificial lab setting with brain tissue injections, researchers said.

Mad cow disease, also known as bovine spongiform encephalopathy, and Creutzfeldt-Jakob disease are only known to be contracted by eating infected animal meat, according to KidsHealth.org.

Comments

[Ed gehrman]

06:33 PM on 10/07/2011

Nothing can evolve without
genetic material. The Prionists at the NIH
never seem to understand that they are conducting experiments with
spiroplasma contaminated tissue. All they’re really doing is experimenting
with spiroplasma. I can’t believe the shared ignorance exhibited by those who continue to buy the prion party line.
The most important and knowledgeable researcher
on TSE and spiroplasma is Dr. Frank Bastian. He implicates, and
certainly proves to the satisfaction of anyone who will listen, the main culprit
behind all TSE infection, including Alzheimer’s: the spiroplasma bacteria.

http://www.sonomacountyfreepress.com/reaction/spiroplasma.html

The case against his elegant research connecting TSE to spiroplasma
infection is superficial and flimsy, including Dr. Gajdusek’s “ashing experiment”
where Dr. Gajdusek suggests “an inorganic template” to explain prions. How do the majority of respected TSE scientists arrive at conclusions that ignore basic biology and the rules of evidence. The prion theory is a red herring. These diseases have the potential to cause more great harm and suffering if we don’t begin to understand them better than we do now.

[SmartladyDem]

02:57 PM on 10/10/2011

That was a fascinating article. To my layman's brain-it appears that there may be arguments that that it is caused by bacteria, fungus or virus-and it even appears to have some auto-immune characteristics.

Would a vaccine or treatment(prophylactic) with antibiotics-or oral antifungal-
be possible?

Sometimes, I do have to wonder if Big Pharma prefers to develop incredibly expensive "Treatments" as apposed to promoting the use of cheap-off patent but effective drugs.
I do understand that we may be constantly exposed to this spiroplasma-
But, perhaps a preventative maintenance program years before vulnerable an exposed groups would ever build up enough plaque to cause dementia.

One other question, why then, does Alzheimer's seem to run in families?
Genetic mutation, vulnerability or is it somehow transmitted in utero?

P.s.-I appreciate you taking your time to read this.

[Terry S Singeltary Sr]

01:33 PM on 10/07/2011

what concerns me here, is the potential for the iatrogenic transmission of Alzheimer's disease. if proven, and there is other science showing the likelihood of this being true, but this would explain a great deal, and would explain the high increase of Alzheimers disease over the last decade. the medical, surgical, dental, blood, tissue, would all be a canidate for potential transmission. we must fund all these TSE prion disease research, and pursuit the cause and cure of these neurological mad cow type TSE prion disease...

Tuesday, October 4, 2011

De novo induction of amyloid-ß deposition in vivo

Molecular Psychiatry advance online publication 4 October 2011; doi: 10.1038/mp.2011.120


http://www.nature.com/mp/journal/vaop/ncurrent/abs/mp2011120a.html


http://betaamyloidcjd.blogspot.com/2011/10/de-novo-induction-of-amyloid-deposition.html


http://transmissiblespongiformencephalopathy.blogspot.com/2011/10/alzheimers-disease-is-transmissible.html


Saturday, March 22, 2008

10 Million Baby Boomers to have Alzheimer's in the coming decades 2008 Alzheimer’s disease facts and figures

http://betaamyloidcjd.blogspot.com/2008/03/10-million-baby-boomers-to-have.html


Saturday, January 22, 2011

Alzheimer's, Prion, and Neurological disease, and the misdiagnosis there of, a review 2011

http://transmissiblespongiformencephalopathy.blogspot.com/2011/01/alzheimers-prion-and-neurological.html


Wednesday, April 27, 2011

GENERATION ALZHEIMER'S: THE DEFINING DISEASE OF THE BABY BOOMERS

http://betaamyloidcjd.blogspot.com/2011/04/generation-alzheimers-defining-disease.html


tss

[Terry S Singeltary Sr]

01:23 PM on 10/07/2011

CJD1/9 0185

Ref: 1M51A

IN STRICT CONFIDENCE

TRANSMISSION OF ALZHEIMER-TYPE PLAQUES TO PRIMATES

http://collections.europarchive.org/tna/20080102191246/http://www.bseinquiry.gov.uk/files/yb/1993/01/05004001.pdf


BSE101/1 0136

IN CONFIDENCE

5 NOV 1992

TRANSMISSION OF ALZHEIMER TYPE PLAQUES TO PRIMATES

http://collections.europarchive.org/tna/20080102232842/http://www.bseinquiry.gov.uk/files/yb/1992/11/04001001.pdf


http://betaamyloidcjd.blogspot.com/


POLITICAL BSe and CJD and THE WOW FACTOR $$$


Monday, September 26, 2011

Variably Protease-Sensitive Prionopathy, Prionpathy, Prionopathy, FFI, GSS, gCJD, hvCJD, sCJD, TSE, PRION, update 2011

http://prionopathy.blogspot.com/2011/09/variably-protease-sensitive-prionopathy.html


Sunday, September 25, 2011

Mad Cow Scaremongers by Terry S. Singeltary Sr. a review of the TSE prion agent 2003-2011

http://transmissiblespongiformencephalopathy.blogspot.com/2011/09/mad-cow-scaremongers.html



Tuesday, October 4, 2011

De novo induction of amyloid-ß deposition in vivo

Molecular Psychiatry advance online publication 4 October 2011; doi: 10.1038/mp.2011.120


http://www.nature.com/mp/journal/vaop/ncurrent/abs/mp2011120a.html


http://betaamyloidcjd.blogspot.com/2011/10/de-novo-induction-of-amyloid-deposition.html


http://transmissiblespongiformencephalopathy.blogspot.com/2011/10/alzheimers-disease-is-transmissible.html