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'Smart Bomb' Mouthwash: Tooth Decay May Be Prevented By Targeting Bad Bacteria, Study Says

Mouthwash Helps Prevent Cavities

First Posted: 11/22/11 02:49 PM ET Updated: 11/22/11 02:49 PM ET

Wenyuan Shi, chair of the oral biology section of the UCLA School of Dentistry, has developed a "smart bomb" mouthwash that targets S. mutans, the bad strain of bacteria responsible for tooth decay, according to CBS Los Angeles.

Researchers tested the formula on 12 participants and found those who rinsed with the mouthwash were free of the S. mutans strain for about four days after the treatment.
Results of the "Smart Bomb" mouthwash study were published in the November issue of the Caries Research journal.

Dr. Shi, who's been working on the drug for about 10 years, told CBS that our mouths are like yards filled with grass and occasional weeds. Other mouthwashes on the market are like herbicides, which kill both the weeds and "surrounding healthy grass." But the new rinse targets only the harmful bacteria without damaging helpful bacteria.

The new mouthwash has been submitted to the Food and Drug Administration (FDA) in the form of a "New Investigational Drug" application, according to a UCLA media release. If the FDA approves the application, the mouthwash will be the first preventative drug developed to fight tooth decay since fluoride revolutionized 20th century oral health. Further research will be conducted starting this spring

According to the Los Angeles Daily News, Americans spend about $70 billion per year on dental care, most of which is concentrated on damage caused by the S. mutans bacteria.

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Filed by Ileana Llorens  |