Debra Messing and her producer/actor husband, Daniel Zelman, have called it quits after a decade-long marriage.
Messing's rep told Us Weekly that the pair amicably separated earlier this year: "The decision was mutual, and they remain supportive of one another and committed to raising their son as a family."
Messing and Zelman, who met as graduate students at New York University, married in 2000 and have a 7-year-old son.
In June 2007, the actress told Redbook magazine that marriage takes "work."
"I'm not one to give out marriage advice. Circumstance has so much to do with whether or not your relationship survives and evolves," she told the magazine. "It's work every day. It's sacrifice and compromise. Life is hard, and it's not in our human nature to compromise quickly and easily. It's something you have to want to learn how to do."
Here, a look back at Messing and Zelman's marriage
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16th Annual Bette Midler's Hulaween, 2011
Debra Messing and husband actor/screenwriter Daniel Zelman attend the 16th Annual Bette Midler's New York Restoration Project's Hulaween at The Waldorf Astoria on October 28, 2011 in New York City.
Photo by Stephen Lovekin/Getty Images
Vanity Fair Oscar Party, 2009
Actress Debra Messing and Daniel Zelman arrive at the 2009 Vanity Fair Oscar Party hosted by Graydon Carter held at the Sunset Tower on February 22, 2009 in West Hollywood, California.
Photo by Michael Buckner/Getty Images
61st Primetime Emmy Awards, 2009
Writer/producer Daniel Zelman and actress Debra Messing arrive at the 61st Primetime Emmy Awards held at the Nokia Theatre on September 20, 2009 in Los Angeles, California.
Photo by Frazer Harrison/Getty Images
F/X 'Damages' Primetime Emmy Awards Party, 2008
Debra Messingand her husband Daniel Zelman attend the F/X 'Damages' Primetime Emmy Awards Party at the Foxtail on September 21, 2008 in Los Angeles, California.
Photo by Noel Vasquez/Getty Images
Playing Guitar Hero III, 2008
Actress Debra Messing and husband Daniel Zelman are seen playing Guitar Hero III: Legends of Rock at The Luxury Lounge in honor of the 2008 SAG Awards featuring Activision, held at the Four Seasons Hotel on January 25, 2008 in Beverly Hills,California.
Photo by Alberto E. Rodriguez/Getty Images
Michael Kors Fashion Show, 2006
Debra Messing and her husband Daniel Zelman attend the Michael Kors Fall 2006 fashion show at Bryant Park during Olympus Fashion Week in New York City.
Photo by Evan Agostini/Getty Images
Los Angeles Confidential Celebration, 2005
Actress Debra Messing and her husband Daniel Zelman attends the 'Los Angeles Confidential Celebration With Gotham Magazine's Cover Star Debra Messing' at the Atrium on March 11, 2005 in Los Angeles, California.
Photo by Mark Mainz/Getty Images
'Along Came Polly' Premiere, 2004
Actress Debra Messing and husband, actor Daniel Zelman attend the Los Angeles premiere of Universal Pictures' film 'Along Came Polly' on January 12, 2004 at the Grauman's Chinese Theatre, in Hollywood, California.
Photo by Vince Bucci/Getty Images
56th Annual Primetime Emmy Awards, 2004
Actress Debra Messing and her husband Daniel Zelman attend the 56th Annual Primetime Emmy Awards at the Shrine Auditorium September 19, 2004 in Los Angeles, California.
Photo by Kevin Winter/Getty Images
52nd Annual Primetime Emmy Awards, 2000
Actress Debra Messing nominated for 'Lead Actress, Comedy Series' in the situation comedy 'Will and Grace' poses with her husband Daniel Zelman during the arrivals to the 52nd Annual Primetime Emmy Awards at the Shrine Auditorium in Los Angeles 10 September, 2000.
Photo LUCY NICHOLSON/AFP/Getty Images
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First Posted: 12/20/11 03:26 PM ET Updated: 12/23/11 05:13 PM ET