'Jeff, Who Lives At Home' Trailer: Jason Segel, Ed Helms Are Depressed Brothers (VIDEO)

Jason Segel and Ed Helms co-star as brothers in "Jeff, Who Lives At Home," the new film from mumblecore writer/directors Jay and Mark Duplass. But if you're looking for some "Hangover" and "Muppets" goofy hijinks, well, get ready for something just a little bit different.

The film features Segel as a lost slacker still loving in his mother's basement, confused and waiting for fate to show him his path in life. Helms plays his only slightly more together brother, whose wife, played by Judy Greer, is having an affair. Their mother, played by Susan Sarandon, is depressed herself, adding to the triangle of familial misery.

A quirky dramedy that is more like Helms' "Cedar Rapids" and Segel's "Forgetting Sarah Marshall" than their raunchy or sillier work, it played at the Toronto Film Festival and is due out on March 16th.

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