Times have certainly changed and so has medicine.
For instance, in the 19th century, opium was a common method for treating coughs and it wasn't until 1923 that it was banned.
These days, opium and derivative drugs like morphine and heroin are illegal, which makes old paraphernalia connected to the days when it was legal very valuable to collectors like Audra Kunkle.
She's the star of the Science Channel series Oddities San Francisco, which airs Saturdays and is filmed at Loved To Death, a San Francisco shop that sells bizarre artifacts like, well, old opium bottles.
Kunkle recently came across two sideshow performers, Molotov and Leighton, who wanted to sell her one as part of a "contraband medicine kit."
"The opium bottle is pretty impressive," she admitted.
Molotov, ever the good businessman, made an additional pitch in hopes of making a sale: "We're not completely out. I believe there is some antique sludge at the bottom."
Kunkle was especially amused by the label: For infants only as directed by the physician.
"I can't imagine giving an infant opium," she said.
"It'd keep him quiet," Molotov volunteered.
In addition, he was hoping to sell an empty bottle of a product called "Mrs. Winslow's Soothing Syrup" that Kunkle said was "commonly known as a baby killer" because it contained a substance called "Laudenum."
"[The product] is actually a mixture of morphine and alcohol that was prescribed for babies when they were colicky," Kunkle explained. "They used to rub it on their gums to help with teething, [but] it would make them lose their appetite so they would die of malnutrition."
Kunkle's employee, Korri Sabatini, summed up the two products succinctly: "You guys are selling us the world's most sinister babysitting kit."
The Loved To Death shop in San Francisco specializes in medical and biological oddities, historical curiosities, Victorian jewelry, and taxidermy dioramas. Oh, and two-headed pigeons.
Loved To Death owner Audra Kunkle is an accomplished taxidermist who has been bringing new life to dead things like this albino raccoon since the shop opened in 2008.
Victorian Lady Chipmunk
One of Kunkle's specialties is creating anthropomorphic dioramas featuring animals in human clothes and human surroundings. It was a popular hobby during the Victorian era that she says "was fascinating, yet so taboo. Even now."
Kunkle tries to use vintage clothes on all her anthropomophic taxidermied animals, but says it's easier to find clothes for birds than mice.
Kunkle doesn't go into her taxidermy project with a set idea, preferring to let the ideas hit her as she's working.
Bird In His Study
Kunkle said when she does an taxidermy piece she recycles a lot of parts that would otherwise being thrown by breeders. In that way, she keeps the animals alive.
Chipmunks Playing The Banjo
When making a taxidermy diorama, Kunkle says it's important to pay attention to detail.
Staff Of 'Oddities San Francisco'
The cast of 'Oddities San Francisco' stand in front of the Loved to Death shop in San Francisco. From left: Wednesday Mourning, Korri Sabatini, Audra Kunckle and Corin Griffin.
Knut The Polar Bear
BERLIN, GERMANY - FEBRUARY 16: A model of Knut the polar bear, that features Knut's original fur, stands on display to the public on its first day at the Natural History Museum on February 16, 2013 in Berlin, Germany. Though Knut, the world-famous polar bear from the Berlin zoo abandoned by his mother and ultimately immortalized as a cartoon film character, stuffed toys, and more temporarily as a gummy bear, died two years ago, he will live on additionally as a partially-taxidermied specimen in the museum. Until March 15, the dermoplastic model of the bear will be on display before it joins the museum's archive, though visitors can see it once again as part of a permanent exhibition that begins in 2014. (Photo by Sean Gallup/Getty Images)