In case you didn't know, Roseanne Barr's number one issue in her presidential campaign is the legalization of marijuana. And she made that point abundantly clear on Tuesday's Late Show with David Letterman.

Parodying Charlton Heston's famous NRA battle cry, Barr said directly to the President, "Obama, you'll get my joint when you pry it out of my cold, dead fingers."

Barr went on to impress that marijuana has real medical benefits, particularly for those with mental illness, "...which is why I use it."

But pot wasn't her only bone to pick. The comedian, who will be roasted by Comedy Central in August, railed against the fact that if you have a medical marijuana prescription you can't own a gun, as well the state of California trying to force porn stars to wear condoms. She then lamented, "The founding fathers are rolling over in their graves on that, Dave!"

Check out the clip above, and if you are currently enjoying your glaucoma medication, here are some GIFs for you to look at.