DETROIT -- Miguel Cabrera homered twice, reaching the 300 mark for his career and helping the Detroit Tigers finish a three-game sweep of the Chicago White Sox with a 6-4 victory Sunday.
Detroit wrapped up a 6-1 homestand against the White Sox and Los Angeles Angels and now leads the AL Central by 1 1/2 games over Chicago. The White Sox have lost five straight.
Cabrera became the second Venezuela-born player to reach 300 home runs. Andres Galarraga hit 399.
Quintin Berry and Brennan Boesch also homered for Detroit to help rookie Jacob Turner (1-1) earn his first career win. Four relievers pitched for the Tigers, with Joaquin Benoit working a perfect ninth for his second save of the year.
Philip Humber (4-5) allowed six runs in three innings. Alex Rios and Kevin Youkilis homered for the White Sox.
The Tigers have won 16 of 21.
Turner, Detroit's rookie right-hander, bounced back after giving up seven runs in two innings in his last start against the Angels. He went 5 1-3 innings, allowing three runs and seven hits. He struck out three without a walk before being lifted after Rios hit a two-run homer in the sixth.
By then, Cabrera and the Detroit offense had already provided plenty of support. After an RBI single in the top of the first by Rios, the Tigers scored three runs in the bottom half before Humber retired a batter. Berry's two-run homer gave Detroit the lead, and Cabrera followed with a high drive that cleared the fence just to the left of center field.
Cabrera's second homer was even longer, off the ivy beyond center. A Tigers spokesman, citing ESPN Stats and Info, said it was estimated at 457 feet.
It was Cabrera's 23rd homer of the year, and he became the 14th player to reach 300 before turning 30, according to STATS, LLC. Cabrera was 29 years, 95 days old Sunday. When Hank Aaron was that age, he had 309 home runs, according to STATS. Barry Bonds had 222 by that age.
Boesch added a two-run shot later in the third to make it 6-1. Humber allowed seven hits and a walk with no strikeouts. He's 3-5 with a 7.55 ERA since pitching a perfect game at Seattle on April 21.
The White Sox chipped away after Humber was taken out. Rios' hit was ruled a homer after umpires consulted replay footage, and Youkilis hit a solo shot off Phil Coke in the seventh.
Octavio Dotel, the third Detroit reliever, came on with one out and a man on in the seventh and retired all five hitters he faced, with four strikeouts.
The White Sox were swept in a series for the first time all season.
NOTES: Coke was pitching for the first time since his wife gave birth to a baby girl. Mickenzie LouAnn was born Saturday morning. ... The Tigers could afford to go deep into their bullpen with an off day coming up Monday. Chicago hosts Minnesota, with RHP Gavin Floyd (7-8) returning from a problem with his throwing elbow to start against Minnesota LHP Francisco Liriano (3-9).