MacFarlane began his introductory remarks speaking into the muted mic, but once he realized the audience couldn't hear him, he walked over to the working mic and broke out his Stewie Griffin voice. "That's what you get for missing rehearsal," he quipped.
Later, MacFarlane tweeted about his misstep:
Oh, THERE'S the fucking mike.
— Seth MacFarlane (@SethMacFarlane) September 24, 2012
RELATED ON HUFFPOST:
HuffPost Entertainment is your one-stop shop for celebrity news, hilarious late-night bits, industry and awards coverage and more — sent right to your inbox six days a week. Learn more