The latest episode of "Taboo" dealt with something more inexplicable than taboo. James Sceville is a big guy, at 350 pounds and 6'3", but he doesn't look like other guys his size. That's because for as long as he can remember, his body has distributed fat almost exclusively to his left side.

It certainly creates for an unexpected visual, with his right arm and leg looking virtually slim compared to their counterparts on his left side. The difference is so severe, his left foot is a full size-and-a-half larger than his right.

He traveled to meet with specialists in New York seeking answers, but what he learned was that he basically had something new and unknown.

"James is one of a kind," a doctor who'd examined him said. "He has some parts of different kind of syndromes, but he doesn’t fit any of the classic characteristics."

James was pleased to learn that his condition wasn't life threatening, and that cosmetic surgery could help balance out his appearance.

See more unexpected stories every week on "Taboo," Tuesdays at 10 p.m. ET on National Geographic.

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  • Fat Betty, "Mad Men"

    <strong>What You'll Need:</strong> A blonde wig with a vintage style, a mumu and plenty of padding <strong>Optional Accessories:</strong> An attractive neck band-aid, a purse full of vintage sweets to snack on all night, a phone programmed to play the <a href="http://www.happyplace.com/15425/a-new-mad-men-theme-song-in-celebration-of-fat-betty-francis">Fat Betty remix of Ram Jam's "Black Betty"</a> on cue.

  • Hibernating Max, "Happy Endings"

    <strong>What You'll Need: </strong>A bucket and/or a furry hat for your head, Wayfarers, a beard, a willingness to go shirtless (or don long underwear), an ability to grunt in a dazed and confused manner, a jar of honey. <strong>Optional Accessories:</strong> A unicycle and a trash can to root around in.

  • Kris Jenner With Swollen Lips, "Keeping Up With The Kardashians"

    <strong>What you'll need</strong>: Giant, red toy lips, short black wig, pajamas, harem of friends to act as your bickering offspring. <strong>Optional accessories</strong>: Pack of q-tips to use to swab your daughters' cheeks for DNA.

  • Rubber Man, "American Horror Story"

    <strong>What You'll Need:</strong> <a href="http://shop.fxnetworks.com/detail.php?p=374908&ecid=PID-5580&pa=SEM-GPA&CAWELAID=1562033894&cagpspn=pla">This, and only this</a>. <strong>Optional Accessories:</strong> Honestly? An empty bladder. (Seriously, this can't be easy to get in and out of.)

  • The Shannon/Thompson Clan, "Here Comes Honey Boo Boo"

    <strong>What You'll Need:</strong> For starters, lots of friends to play along. Assuming you have that, start with a variety of tops including t-shirts from local business/agencies, shirts with Angry Birds on them, shirts with sassy sayings and shirts in generic colors. For bottoms, go with jeans, cut-offs or brightly colored shorts. If you want to go pageant wear, <a href="http://www.thebrandur.com/Alana-HONEY-BOO-BOO.html">here are the tees you need</a>. <strong>Optional Accessories:</strong> Forklift foot, sketti, pepper to make you sneeze and double as gnats and/or Glitzy the Pig.

  • "Luck's" Unluckiest Castmembers

    <strong>What You'll Need:</strong> Several friends to gallop around with and a <a href="http://www.fredflare.com/APARTMENT/Horse-Head-Mask/">creepily realistic horse mask</a> for each person <strong>Optional Accessories: </strong>A Dustin Hoffman gangster-type, horse trainers with unintelligible accents, someone with a PETA-stamped "Save The Horses" picket sign

  • Saul Berenson, "Homeland"

    <strong>What You'll Need:</strong> Open-neck shirt with the sleeves rolled up, a lush but neatly trimmed salt-and-pepper beard, sensible Dad glasses, a look in your eyes that is both penetrating and compassionate, sensible shoes. <strong>Optional accessories:</strong> Shades and a jaunty straw hat for field missions, extra meds for Carrie, loaf of Challah bread (to quote Claire Danes at the Emmys: "Mandy Patinkin, Challah!")

  • Purrfect, "The Voice"

    <strong>What You'll Need:</strong> White pants, cat years and a t-shirt with Cee Lo's face on it <strong>Optional Accessories:</strong> A sign that reads: "CAT FOR HIRE," Someone dressed like a pink cockatoo, Someone dressed like Cee Lo (with necessary sunglasses)

  • Sister Jude, "American Horror Story: Asylum"

    <strong>What You'll Need:</strong> A nun's habit, a <a href="http://www.spencersonline.com/product/al-riding-crop-black/">riding crop</a> and a good scowl. <strong>Optional Accessory: </strong>An Emmy award.

  • Dr. Rizzo, "Animal Practice"

    <strong>What You'll Need:</strong> A stethoscope, lab coat, fangs and black nail polish. <strong>Optional Accessories:</strong> Excessive facial/body hair, a banana, an actual doctor to perch on the shoulder of.

  • One-Night Stand Doctor, "The Mindy Project"

    <strong>What You'll Need: </strong>A sequined short dress (ideally in a jewel tone), a white doctor's coat and a stethoscope <strong>Optional Accessories:</strong> A doctor's bag with some stilettos and a condom, A male nurse with some messy hair

  • Ron Swanson At A BBQ, "Parks & Recreation"

    <strong>What you'll need:</strong> Fake mustache, masculine-themed cooking apron, meat smoker attached to your car, toy pig. <strong>Optional accessory:</strong> Bacon to hand out to trick-or-treaters.

  • The Dowager Countess, "Downton Abbey"

    <strong>What You'll Need: </strong>A hat, cane, corset, floor-length gown and stern expression. <strong>Optional Accessories:</strong> Maids, a cup of tea.