Those chosen for the list are shot by a renowned photographer, this year Michael Sharkey, who has blogged for HuffPost Gay Voices in the past, and featured both in the magazine's December/January double issue and on Out.com.
Honorees are chosen from all walks of life and include celebrities, writers, politicians, activists, sports figures and artists, among others.
The Out 100 cover stars this year include "Glee" star Jane Lynch, "RuPaul's Drag Race" season four winner Sharon Needles, "The New Normal" star Andrew Rannells and '80s icon Boy George.
Other honorees include Elton John and his husband David Furnish, trans model and designer Isis King, HuffPost Gay Voices Editor-at-Large Michelangelo Signorile, New York City Council Speaker Christine Quinn and her wife Kim Catullo, actor Michael Urie and 14 LGBT members of the Obama-Biden administration.
Out magazine will throw a party to celebrate the Out 100 in late November in New York City.
In the comments section tell us who you would nominate for LGBT person of the year.