Including lots of nutrient-rich vegetables in your diet is associated with a decreased risk of a specific type of breast cancer, according to a new study in the Journal of the National Cancer Institute.
The study, conducted by researchers at Brigham and Women's Hospital, included analyzing data from 20 different studies, where 993,466 women were followed for 11 to 20 years. The researchers analyzed the women's fruit and vegetable consumption as well as their breast cancer development -- along with their type of breast cancer -- throughout the years.
The researchers did not find an association between eating fruits and vegetables and overall breast cancer risk, nor did they find an association between produce consumption and risk of a subtype of breast cancer called estrogen receptor-positive breast cancer.
But, they did find an association between higher vegetable intake and a decreased risk of estrogen receptor-negative breast cancer. The association between fruit consumption and estrogen receptor-negative breast cancer was not statistically significant, though.
However, in an accompanying editorial, experts from the University of Arizona Cancer Center pointed out that merely an association was noted, and other health behaviors could play a major role in the decreased risk of this breast cancer subtype.
Still, including lots of good-for-you vegetables in your diet can never be a bad thing. For more superfoods that have the potential to protect you from breast cancer, click through the slideshow:
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Broccoli And Broccoli Sprouts
Cruciferous vegetables, but broccoli in particular, make for anti-cancer powerhouses thanks in part to a compound called sulforaphane that actually helps the body fight the spread of tumors. Recent research revealed the underlying reason: sulforaphane may inhibit an enzyme, called an HDAC, that <a href="http://www.huffingtonpost.com/2012/02/29/broccoli-cancer-sulforaphane_n_1310634.html">works to suppress the body's tumor fighting ability</a>, as we've previously reported. And sprouts are even more potent: three-day old broccoli sprouts have 20 to 50 times the sulforaphanes as mature broccoli, <a href="http://www.hopkinsmedicine.org/press/1997/sept/970903.htm">according to Johns Hopkins research</a>. For more about the cancer fighting properties of <em>all cruciferous vegetables, check HuffPost blogger Dr. Joel Fuhrman's <a href="http://www.huffingtonpost.com/joel-fuhrman-md/cancer-prevention_b_1624965.html">analysis of cabbage, brussels sprouts, bok choy and more</a>.
Garlic is considered a cancer-fighting food for several forms of the disease, <a href="http://www.cancer.gov/cancertopics/factsheet/prevention/garlic-and-cancer-prevention#r12">according to the National Cancer Institute</a>. One French study found that women who regularly ate garlic had <a href="http://www.ncbi.nlm.nih.gov/pubmed/9928867">a significantly reduced risk of breast cancer</a>. Garlic's mild cousin, onions also had a protective effect, according to the study.
Pomegranates are known for their anti-cancer properties, thanks to a richness in anti-inflammatory antioxidants, polyphenols. But they may offer a specific benefit against breast cancer: research shows that a phytochemical found in abundance in pomegranates, called ellagitannins, interfere in the production of aromatase, an enzyme that, as HuffPost blogger Dr. Nalini Chilkov explained, "<a href="http://www.huffingtonpost.com/nalini-chilkov/pomegranates-cancer-fighting-_b_1078343.html">increases hormone production in breast tissue</a>." That's important because breast cancer is hormone-dependent, meaning that it feeds off of hormones like estrogen to grow and spread. "Hormone dependent cancers such as breast cancer are commonly treated with aromatase inhibitors, which block this enzyme," wrote Chilkov.
Although preliminary, research in mice has found that <a href="http://www.sciencedaily.com/releases/2011/09/110901163921.htm">including walnuts in a healthful diet throughout the entire lifespan</a> reduced the risk of developing breast cancer by <em>half</em>.
Curcumin, the compound in turmeric, may play a role in blocking the expression of a molecule called RANKL, <a href="http://www.huffingtonpost.com/nalini-chilkov/turmeric-health-benefits-_b_828856.html">which is found in the most deadly and aggressive breast cancer tumor cells</a>.
Most research regarding flax's anti-cancer properties has been done in mice or in-vitro cell cultures, but what it shows could be profound: in one study, according to the American Cancer Society, <a href="http://www.cancer.org/Treatment/TreatmentsandSideEffects/ComplementaryandAlternativeMedicine/HerbsVitaminsandMinerals/flaxseed">the lignans found in flax slowed the movement and "stickiness" of breast cancer cells</a>, causing it to spread more slowly in a cell culture simulation.
Berries have several powerful antioxidants, primarily anthocyanins and ellagic acid, which have been shown in cell culture studies to <a href="http://www.aicr.org/foods-that-fight-cancer/blueberries.html#research">reduce free radical damage to healthy cells</a>, according to the American Institute for Cancer Research. In separate research, they were shown to slow the growth and shorten the lifespan of breast cancer (as well as mouth, colon and prostate cancer) cells.
Green tea is rich in the polyphenol EGCG (epigallocatechin-3-gallate), which has been shown to slow the spread of breast cancer cells, <a href="http://www.breastcancer.org/tips/nutrition/supplements/known/green_tea">according to breastcancer.org</a>.
Tomatoes are rich in the antioxidant lycopene, which is thought to <a href="http://www.msnbc.msn.com/id/39726407/ns/health-cancer/t/what-you-should-eat-avoid-beat-breast-cancer/#.UHNMJvmMG5M">slow breast cancer cell growth</a>.