HOUSTON — Miguel Cabrera hit two home runs and tied a career with six RBIs to lead the Detroit Tigers' 17-2 mauling of the Houston Astros on Saturday night.

Max Scherzer (4-0) won his fourth straight to begin the season, allowing one run on three hits and striking out eight in eight innings. Detroit has won its first three games against Houston and has won eight of its last nine.

Scherzer allowed a leadoff single to Robbie Grossman in the first and sent down the next 16 batters until Matt Dominguez hit a two-out single in the sixth.

Cabrera drove in six runs for the fifth time in his career. The last time was against Oakland on Sept. 18, 2012. Cabrera has 10 hits in his last 20 at-bats over his last five games.

Torii Hunter had four hits and drove in two runs as every Tiger starter had a hit. Victor Martinez drove in four and had a two-run homer in the ninth. The 17 runs are the most scored by the Tigers since Sept. 4, 2011, when they had 18 against the White Sox. The 15-run loss was Houston's most lopsided defeat since a 19-3 loss to Colorado on Sept. 25, 2011.

Houston (8-23) has the worst record in the majors, having lost five in a row and nine of its last 10 games.

Detroit, which scored at least one run in every inning except the third, got to Houston starter Lucas Harrell (3-3) quickly, scoring six times in the first two innings.

Cabrera followed singles by Austin Jackson and Hunter with an RBI single to make it 1-0, and two batters later, Andy Dirks doubled to score two more. Two batters later, Jhonny Peralta singled to bring home Dirks and give Detroit a 4-0 lead.

Cabrera upped the lead to 6-0 in the second with a monstrous two-run home run off the facade in left field.

Detroit made it 7-0 in the fourth with a bases-loaded walk by Cabrera, and Alex Avila extended the lead to 8-0 with an RBI double in the fifth.

Cabrera started the sixth by sending a Jose Cisnero offering off the facade in deep left field, his second home run making it 9-0 and giving him his 26th multi-homer game.

Hunter, Cabrera and Prince Fielder added run-scoring singles in the seventh, and Peralta, Omar Infante and Hunter each had an RBI in the eighth.

Carlos Corporan ended the shutout with a solo home run in the seventh, and Jason Castro had a run-scoring single in the ninth.

Harrell was hammered for eight runs on 10 hits with three strikeouts and four walks in 4 1-3 innings. Harrell's ERA ballooned from 3.60 to 5.03. He had entered Saturday's game having won three in a row and had allowed five runs in 24 2-3 innings over his last four starts.

NOTES: Detroit Tigers reliever Drew Smyly has thrown 13 consecutive scoreless innings dating to April 12 following two scoreless innings Friday night. . Detroit OF Jackson extended his hitting streak to nine games with a first-inning single. . Houston entered Saturday's game leading the majors with 40 double plays turned. . RHP Philip Humber (0-6.7.58 ERA) goes to the mound for the Astros Sunday in search of his first win of the season, while Tigers will counter with RHP Justin Verlander, who is 3-2 with a 1.83 ERA.

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  • Who's Your Tiger?

    They win ballgames (sometimes), they hit homers, they steal bases and they hug a lot. Say hello to your Detroit Tigers. We've collected some of our favorite photos from this season of the boys in blue and orange. Click through to pick your favorite player. Caption: Detroit Tigers' Miguel Cabrera, center, and Delmon Young, right, celebrate the Tigers' 5-1 win over the Minnesota Twins in a baseball game Wednesday, Aug. 15, 2012 in Minneapolis. Both Young and Cabrera homered in the game. At left is Prince Fielder.

  • Jim Leyland

    Detroit Tigers manager Jim Leyland blows a bubble before the first inning of a baseball game against the St. Louis Cardinals in Detroit, Tuesday, June 19, 2012.

  • Miguel Cabrera

    Miguel Cabrera #24 of the Detroit Tigers talks to members of the Boston Red Sox during the game on July 31, 2012 at Fenway Park in Boston, Massachusetts.

  • Anibal Sanchez

    Anibal Sanchez #19 of the Detroit Tigers delivers a pitch against the Minnesota Twins during the first inning on August 13, 2012 at Target Field in Minneapolis, Minnesota.

  • Avisail Garcia

    Avisail Garcia #34 of the Detroit Tigers slides into third base with a bases loaded triple against the Minnesota Twins in the sixth inning at Comerica Park on May 26, 2013 in Detroit, Michigan.

  • Doug Fister

    Detroit Tigers starting pitcher Doug Fister warms up against the Washington Nationals before the first inning of a spring training baseball game in Viera, Fla., Sunday, March 18, 2012.

  • Max Scherzer

    Detroit Tigers starter Max Scherzer delivers a pitch in the first inning during a baseball game against the Chicago White Sox in Chicago, Tuesday, May, 15, 2012.

  • Torii Hunter

    Torii Hunter #48 of the Detroit Tigers looks on before the Opening Day game against the Minnesota Twins on April 1, 2013 at Target Field in Minneapolis, Minnesota. The Tigers defeated the Twins 4-2.

  • Omar Infante

    Toronto Blue Jays' Colby Rasmus is forced out on second by Detroit Tigers' Omar Infante, who misses the double play during the fifth inning of a baseball game, Saturday, July 28, 2012, in Toronto.

  • Jhonny Peralta

    Detroit Tigers' Jhonny Peralta celebrates a three run home run against the Toronto Blue Jays during second inning of a baseball game in Toronto Sunday, July 29, 2012.

  • Joaquin Benoit

    Detroit Tigers relief pitcher Joaquin Benoit leaves the dugout en route to the bullpen after finishing his pitching duties in the fifth inning of a spring training baseball game against the Toronto Blue Jays, Monday, March 5, 2012, in Lakeland, Fla.

  • Rick Porcello

    Detroit Tigers pitcher Rick Porcello throws against the Seattle Mariners in the first inning of a baseball game in Detroit, Thursday, April 26, 2012.

  • Prince Fielder

    Prince Fielder #28 of the Detroit Tigers waits to bat against the Baltimore Orioles during the sixth inning at Oriole Park at Camden Yards on July 14, 2012 in Baltimore, Maryland.

  • Jose Valverde

    Jose Valverde #46 of the Detroit Tigers reacts after beating the Tampa Bay Rays 5-2 at Comerica Park on April 10, 2012 in Detroit, Michigan.

  • Justin Verlander

    Detroit Tigers pitcher Justin Verlander acknowledges the crowd after defeating the Pittsburgh Pirates 6-0 in an interleague baseball game, Friday, May 18, 2012, in Detroit. Verlander threw a one-hitter.

  • Don Kelly

    Don Kelly #32 of the Detroit Tigers scores the winning run in the bottom of the ninth inning during an MLB game against the Kansas City Royals at Comerica Park on September 27, 2012 in Detroit, Michigan. The Tigers won 5-4.

  • Alex Avila

    Detroit Tigers catcher Alex Avila (13) tags Los Angeles Angels' Erick Aybar out at home plate in the third inning of a baseball game in Detroit, Monday, July 16, 2012.

  • Andy Dirks

    Detroit Tigers' Andy Dirks dives into third base with a triple against the Minnesota Twins in the third inning of a baseball game Saturday, Sept. 22, 2012, in Detroit.

  • Matt Tuiasosopo

    Detroit Tigers' Matt Tuiasosopo smiles in the dugout after hitting a solo home run during the fifth inning of an exhibition spring training baseball game against the St. Louis Cardinals, Saturday, March 16, 2013, in Jupiter, Fla. Detroit won 3-0.

  • Phil Coke

    Detroit Tigers relief pitcher Phil Coke checks out Rocky, a 4-week-old Bengal tiger from the Dade City Wild Things Zoo, before an exhibition spring training baseball game against the Tampa Bay Rays, Friday, March 29, 2013 in Lakeland, Fla.

  • Darin Downs

    Detroit Tigers manager Jim Leyland, right, watches relief pitcher Darin Downs throw during a baseball spring training workout Tuesday, Feb. 19, 2013, in Lakeland, Fla.

  • Victor Martinez

    Victor Martinez #41 of the Detroit Tigers reacts to a called third strike during the first inning of the Opening Day game against the Minnesota Twins on April 1, 2013 at Target Field in Minneapolis, Minnesota.

  • Jose Ortega

    Jose Ortega #56 of the Detroit Tigers pumps his fist after getting Matt Dominguez of the Houston Astros to ground out to end the game at Comerica Park on May 13, 2013 in Detroit, Michigan. The Tigers defeated the Astros 7-2.

  • Rick Porcello

    Detroit Tigers pitcher Rick Porcello runs in the outfield before a baseball spring training exhibition game against the Toronto Blue Jays, Wednesday, March 6, 2013, in Lakeland, Fla.

  • Ramon Santiago

    Detroit Tigers second baseman Ramon Santiago, top, and Colorado Rockies' Carlos Gonzalez watch after Santiago completed the double play on a Michael Cuddyer ground ball in the sixth inning of a baseball game in Detroit, Saturday, June 16, 2012.

  • Drew Smyly

    Detroit Tigers starting pitcher Drew Smyly delivers in the third inning against the Philadelphia Phillies in a spring training baseball game in Clearwater, Fla., Tuesday, March 12, 2013.

  • Bryan Villarreal

    Detroit Tigers relief pitcher Brayan Villarreal stretches during a baseball spring training workout Friday, Feb. 15, 2013, in Lakeland, Fla.

  • Brayan Pena

    Detroit Tigers third base coach Tom Brookens (61) greets Tigers Brayan Pena (55) after Pena's two-run, fifth-inning home run off Tigers reliever Jacob Diekman in their spring training baseball game in Clearwater, Fla., Tuesday, March 12, 2013. The Tigers defeated the Phillies 10-6.

  • Bros Forever!

    Detroit Tigers pitcher Justin Verlander, left, first baseman Prince Fielder, center, and third baseman Miguel Cabrera, right, react after being presented with their All-Star jerseys before a baseball game against the Kansas City Royals in Detroit, Friday, July 6, 2012.

  • Luke Putkonen

    Luke Putkonen #36 of the Detroit Tigers pitches in the 14th inning against the Houston Astros at Minute Maid Park on May 2, 2013 in Houston, Texas.