San Diego's Everth Cabrera was one of 12 players to accept a 50-game suspension for violations of Major League Baseball's Joint Drug Prevention and Treatment Program, the league announced on Monday.
New York Yankees star Alex Rodriguez was suspended through the 2014 seaspn.
MLB commissioner Bud Selig released a statement on the suspensions.
More from the Associated Press
SAN DIEGO (AP) — Padres general manager Josh Byrnes says the suspension of All-Star shortstop Everth Cabrera by Major League Baseball is "a painful but necessary step."
Cabrera was banned for 50 games Monday for his relationship to Biogenesis of America, a closed anti-aging clinic in Florida accused of distributing banned performing-enhancing drugs.
While disappointed, Byrnes says the Padres support MLB and the union in their attempts to clean up the game.
The GM called it "a big day for Major League Baseball and the players who've been clean for some time. Their voices are being heard."
The switch-hitting Cabrera leads the NL with 37 stolen bases. Last year, he led the NL with a career-high 44 steals.
Padres catcher Yasmani Grandal was suspended the first 50 games of the season for testing positive to testosterone. He's out for the season with a knee injury.