But in a new interview with The Border Mail, an Australian newspaper, she revealed that she has found happiness again.
When a reporter for the paper asked the actress if she is happier now post-split, Kidman hesitated for a moment before answering in the affirmative.
"Yes," said. "Happy in the sense that I have my girls and my husband and I have a very, very strong real life to counter-balance my fantasy life now. My fantasy life used to outweigh that more and now I've kind of balanced it, which is a lot healthier."
And although The Border Mail reports that Kidman's PR person whisked her out of the room after that question, the actress turned back to assure the reporter of her happiness: "I smile now!" she said.
Kidman has been married to country star Keith Urban since June 2006, and the couple has two daughters together.
Click through the slideshow below to see what Kidman and other stars have had to say about struggling with depression after divorce.
In an interview in the October 2012 issue of Australia's WHO magazine, Nicole Kidman opened up about life after her 2001 divorce from Tom Cruise, which she described as "the loneliest, loneliest existence." She added: "I married [Tom] really fast and really young, but I don't regret that because it got me Bella and Connor, and I did have a fantastic marriage for a long period. Then when it didn't work out, I had to really dig deep and find my way through depression, but I have no regrets about all of it. It was all a part of growing up."
After seven years of marriage, Reese Witherspoon filed to divorce Ryan Phillippe in November 2006. After the split, Phillippe admitted that he struggled with depression. In a 2008 interview with W magazine, he described the period as "the darkest, saddest place I had ever been." "It was a struggle--there were a good four or five months of not being able to get out of bed. It was the worst time in my life," he said. "You get through it. It's a process that's not easy, but I get less and less sad about it every day."
In 2010, Emma Thompson told BBC Radio that following her divorce from actor and "Thor" director Kenneth Branagh in 1995, she dealt with a "very rough" period. "I don't think I did stay sane," she told host Kirsty Young. "I should have sought professional help. Divorce. Ghastly, painful business."
In a 2007 interview with Parade magazine, Halle Berry admitted to being so distraught after her 1996 split from baseball player David Justice that she contemplated suicide. "I was sitting in my car, and I knew the gas was coming when I had an image of my mother finding me," she told the magazine. But Berry reportedly claimed that Parade "sensationalized some old material" about her suicide attempt, noting that the information was actually pulled from earlier interviews with Larry King and Oprah. (Parade denied the accusation.)
Amid rumors of Ethan Hawke's philandering, Uma Thurman filed for divorce from the "Training Day" actor in 2004 after six years of marriage. In a sit-down interview with Oprah in 2005, she called the break up "excruciating." A year later, she elaborated on the pain she felt in the wake of the split: "My professional life was soaring, but my private life was in ruins," Contact Music quoted Thurman as saying. "For many years, I lived in a kind of self-loathing where I never gave myself much credit for anything I accomplished."