ABC's 'This Week' will air an interview with President Obama on Sunday, the network announced Thursday.
The interview, with George Stephanopoulos, is the president's first since his pivotal Syria speech.
Obama will address the crisis in Syria, as the United States works with Russia to help ease the conflict.
On Thursday, Secretary of State John Kerry began his two-day negotiations with Russian officials. Kerry rejected Syrian President Bashar Assad's offer for a 30-day deadline to submit information on his administration's chemical weapons.
"This is not a game," Kerry said. "It has to be real. It has to be comprehensive. It has to be verifiable. It has to be credible. It has to be timely and implemented in a timely fashion. Finally, there ought to be consequences if it doesn't take place."
On 'This Week', Obama will also discuss domestic issues, such as congressional budget negotiations and the economy.