Nicole Holofcener's "Enough Said" features many highlights -- among them, James Gandolfini's final lead performance -- but it's the casting of three supporting roles that stands out most of all.

Holofcener's film, about two divorcees (Gandolfini and Julia Louis-Dreyfus) trying to navigate the tricky waters of middle-aged love, features great turns from Tracey Fairaway as Louis-Dreyfus' onscreen daughter, Rookie magazine founder Tavi Gevinson as Fairway's onscreen friend and Eve Hewson, a.k.a. Bono's daughter, as Gandolfini's onscreen progeny.

Born on July 7, 1991, Hewson is the daughter of the U2 frontman (whose real name is Paul Hewson) and Irish activist Alison Hewson. "Enough Said" marks her highest profile film role to date (she also co-starred with Sean Penn in "This Must Be The Place").

"Both my parents were against [acting]," she told The National Post at a screening of "Enough Said" earlier this month. "It's because they know that world and it's really hard. … The rejection is awful, the competition is terrifying and you’re constantly up and down. They were like, 'No, no, no, please, no!' I had to really fight for it."

eve hewson enough said

Below, check out photos of Hewson, 22, in "Enough Said" and at the film's various premieres. The film is out in theaters now.

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  • Eve Hewson, James Gandolfini

    This publicity photo released by Fox Searchlight shows James Gandolfini, left, and Eve Hewson in a scene from the film, “Enough Said." (AP Photo/Fox Searchlight, Lacey Terrell)

  • Eve Hewson

    Eve Hewson attends a special screening of "Enough Said" on Monday, Sept. 16, 2013, in New York. (Photo by Charles Sykes/Invision/AP)

  • "Enough Said" New York Screening - Red Carpet

    NEW YORK, NY - SEPTEMBER 16: Eve Hewson attends 'Enough Said' New York Screening at Paris Theater on September 16, 2013 in New York City. (Photo by Rob Kim/Getty Images)

  • "Enough Said" New York Screening - Red Carpet

    NEW YORK, NY - SEPTEMBER 16: Eve Hewson attends 'Enough Said' New York Screening at Paris Theater on September 16, 2013 in New York City. (Photo by Rob Kim/Getty Images)

  • Nicole Holofcener, Toni Collette, Eve Hewson, Catherine Keener

    Wriet-director Nicole Holofcener, second from left, of the film "Enough Said," poses with cast members, from left, Eve Hewson, Toni Collette and Catherine Keener on day 4 of the 2013 Toronto International Film Festival on Sunday, Sept. 8, 2013 in Toronto. (Photo by Chris Pizzello/Invision/AP)

  • Nicole Holofcener, Toni Collette, Eve Hewson, Catherine Keener

    Wriet-director Nicole Holofcener, second from left, of the film "Enough Said," poses with cast members, from left, Eve Hewson, Toni Collette and Catherine Keener on day 4 of the 2013 Toronto International Film Festival on Sunday, Sept. 8, 2013 in Toronto. (Photo by Chris Pizzello/Invision/AP)

  • Toni Collette, Julia Louis Dreyfus, Tracey Fairaway , Eve Hewson, Tavi Gevinson, Catherine Keener

    IMAGE DISTRIBUTED FOR FOX SEARCHLIGHT - Toni Collette, Julia Louis Dreyfus, Tracey Fairaway , Eve Hewson, Tavi Gevinson and Catherine Keener are seen at Fox Searchlight's Premiere of "Enough Said", on Saturday, September 7th, 2013 in Toronto, Canada. (Photo by Todd Williamson/Invision for Fox Searchlight/AP Images)

  • Toni Collette, Julia Louis Dreyfus, Tracey Fairaway , Eve Hewson, Tavi Gevinson, Catherine Keener

    IMAGE DISTRIBUTED FOR FOX SEARCHLIGHT - Toni Collette, Julia Louis Dreyfus, Tracey Fairaway , Eve Hewson, Tavi Gevinson and Catherine Keener are seen at Fox Searchlight's Premiere of "Enough Said", on Saturday, September 7th, 2013 in Toronto, Canada. (Photo by Todd Williamson/Invision for Fox Searchlight/AP Images)

  • Variety Studio Presented By Moroccanoil At Holt Renfrew - Day 1 - 2013 Toronto International Film Festival

    Actress Eve Hewson attends the Variety Studio presented by Moroccanoil at Holt Renfrew during the 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Michael Buckner/Getty Images for Variety)

  • "Enough Said" Premiere - Arrivals - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson arrives at the 'Enough Said' premiere during the 2013 Toronto International Film Festival at The Elgin on September 7, 2013 in Toronto, Canada. (Photo by Jason Kempin/Getty Images)

  • Variety Studio Presented By Moroccanoil At Holt Renfrew - Day 1 - 2013 Toronto International Film Festival

    (L-R) Actress Catherine Keener, filmmaker Nicole Holofcener and actress Eve Hewson speak at the Variety Studio presented by Moroccanoil at Holt Renfrew during the 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Michael Buckner/Getty Images for Variety)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: (L-R) Actress Tavi Gevinson, director/screenwriter Nicole Holofcener, actress Julia Louis-Dreyfus, actress Tracey Fairaway, actress Eve Hewson and actress Catherine Keener of 'Enough Said' pose at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: (L-R) Actress Tavi Gevinson, director/screenwriter Nicole Holofcener, actress Julia Louis-Dreyfus, actress Tracey Fairaway, actress Eve Hewson and actress Catherine Keener of 'Enough Said' pose at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Premiere - Arrivals - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson arrives at the 'Enough Said' premiere during the 2013 Toronto International Film Festival at The Elgin on September 7, 2013 in Toronto, Canada. (Photo by Jason Kempin/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson of 'Enough Said' poses at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson of 'Enough Said' poses at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson of 'Enough Said' poses at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: Actress Eve Hewson of 'Enough Said' poses at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: (L-R) Actress Tavi Gevinson, director/screenwriter Nicole Holofcener, actress Julia Louis-Dreyfus, actress Tracey Fairaway, actress Eve Hewson and actress Catherine Keener of 'Enough Said' pose at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: (L-R) Actress Tavi Gevinson, director/screenwriter Nicole Holofcener, actress Julia Louis-Dreyfus, actress Tracey Fairaway, actress Eve Hewson and actress Catherine Keener of 'Enough Said' pose at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)

  • "Enough Said" Portraits - 2013 Toronto International Film Festival

    TORONTO, ON - SEPTEMBER 07: (L-R) Actress Tavi Gevinson, director/screenwriter Nicole Holofcener, actress Julia Louis-Dreyfus, actress Tracey Fairaway, actress Eve Hewson and actress Catherine Keener of 'Enough Said' pose at the Guess Portrait Studio during 2013 Toronto International Film Festival on September 7, 2013 in Toronto, Canada. (Photo by Larry Busacca/Getty Images)