Meg Ryan Will Reunite With Tom Hanks For New Film

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(EXCLUSIVE, Premium Rates Apply) NEW YORK - MARCH 10: Actress Meg Ryan and Actor Tom Hanks at the 23rd Annual Rock and Roll Hall of Fame Induction Ceremony at the Waldorf Astoria on March 10, 2008 in New York City. *EXCLUSIVE* (Photo by Kevin Mazur/WireImage) | Kevin Mazur via Getty Images

Meg Ryan will make her directorial debut with "Ithaca," an adaptation of William Saroyan‘s novel "The Human Comedy," which frequent co-star Tom Hanks will executive-produce.

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