Osbourne stopped by HuffPost Live on Wednesday, April 9, to extol the virtues of her "dear friend" and set the record straight about the 21-year-old.
"I'm proud of her because whether you agree with what she does or not, she stands by her guns and she's not fake," she told Caitlyn Becker.
Still, Osbourne was quick to dismiss comparisons between Cyrus and Justin Bieber.
"You can't paint them with the same brush," Osbourne said. "They're two completely different people."