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David Katz, M.D.

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The Case For Walnuts

Posted: 08/15/11 09:18 AM ET

I am just back (on the red eye, no less) from the annual Scientific Advisory Committee meeting of the California Walnut Commission held in Napa Valley. If you could live in Napa Valley, why would you live anywhere else? If you've been, you know what I mean.

The California Walnut Commission is the trade group representing walnut growers in the U.S., most of whom have their ranches in California. The commission is involved in some marketing, messaging and PR -- but overwhelmingly oversees the research agenda examining the health effects of walnut intake. And that, of course, is where I come in -- and why I was at the meeting.

My lab has completed two studies of walnuts, and I was in Napa to present the second, as well as to participate in discussions of future research priorities.

Our first study, published in Diabetes Care in 2010, showed that adding walnuts to the daily diet of adults with Type 2 diabetes for two months significantly improved blood vessel health, as measured by something called endothelial function.

Well known to clinicians, especially cardiologists, and to researchers, endothelial function is not generally familiar to the public at large. In brief, ultrasound is used to measure the ability of blood vessels to dilate when they should. Normal endothelial function is a very strong indicator of low heart disease risk; endothelial dysfunction portends the converse.

Walnuts added to the diet improve endothelial function in Type 2 diabetes. Our study also showed that even though we were adding walnuts, and thus calories, to the diet -- weight gain did not result. Our study subjects did not gain weight, because they made room in their diets for the walnut calories.

Like other nuts, walnuts are energy dense (i.e., high in calories) -- but especially when eaten as nature provides them, without additions of sugar or salt, they are very satiating, providing a lasting feeling of fullness. Satiety is, in essence, the ROI for calories consumed, and it appears to be very high for nuts in general, and walnuts specifically.

Our more recent study examined a potential role for walnuts in diabetes prevention. Using a similar design, and measures, we examined effects of roughly 14 walnuts a day for two months in overweight adults with signs of the metabolic syndrome, a state that anticipates diabetes. Our results are just in, and will be submitted for publication shortly. In brief, they closely mimic the results of study one: endothelial function improved, as did blood pressure, with no weight gain.

Results from my lab were just a small part of a rich, two-day conversation about the diverse health effects of walnut intake, and underlying mechanisms. Scientists from throughout the U.S., from Spain and from Australia contributed.

Studies were presented indicating that walnuts confer health benefits when included in the Mediterranean diet; are effective at increasing satiety and controlling appetite; contain uniquely active antioxidants; may prevent cancer progression; reduce inflammation; influence gene expression; and may help reduce body fat. They may also enhance male fertility.

With regard to mechanisms -- and the active ingredients in walnuts -- discussion was equally far-ranging. Like most nuts, walnuts are rich in unsaturated oils, minerals (magnesium, calcium and potassium), fiber, protein and antioxidants. Unlike other nuts, walnuts are rich in omega-3 fat, in the form of ALA (alpha linolenic acid).

There is, as some of you likely know, ongoing debate about the relative health benefits of plant omega-3 in the form of ALA, and marine animal omega-3, which comes as EPA and DHA. As was explored in some detail by the biochemists at our meeting, ALA converts inefficiently into EPA and DHA in the human body. But, on the other hand, it may exert complementary health benefits of its own, and clearly influences the composition of our cells, and hormone production.

While much discussion focused on the "active" ingredients in walnuts -- an inevitable consequence of our often reductionistic approach to science -- the consensus was clear that the active ingredient in walnuts is almost certainly ... walnuts. Studies were presented indicating explicitly that many of those parts exert benefits even in isolation, but that the health effect of the whole is greater than a mere summing of the parts we know.

Even as we met, results of a meta-analysis by Harvard researchers, involving some 200,000 study participants, were published online in the American Journal of Clinical Nutrition. The study shows that regular intake of processed meat, and to a lesser extent any red meat, increases diabetes risk substantially. Conversely, more intake of nuts (as well as whole grain and low-fat dairy) and less intake of meat can reduce diabetes risk by as much as 35 percent. So says Dr. Frank Hu, senior author of the meta-analysis, and a participant at the Napa meeting.

I can say one more thing about walnuts: when the overall nutritional quality of nuts is measured comprehensively, they come out on top. On the NuVal scale from 1 to 100, which has itself been validated against health outcomes in 100,000 people, walnuts score 82. Almonds are close behind at 81, but virtually no other nut comes close. Pistachios score 69; pecans, 67; peanuts, 29; and cashews, 25.

It is perhaps to be expected that a group of scientists studying walnuts, and attending a walnut commission meeting, would be walnut fans. In other words, you might dismiss our enthusiasm as bias. But there are two reasons why I believe you shouldn't.

First, the peer-reviewed science supporting health benefits from walnut intake is broad, and deep, and has had to run a gauntlet of filters designed to weed out biased work. Second, the groups' bias in favor of walnuts is cart, not horse. The evidence generated by robust research has made proponents of us all -- we didn't just start out that way.

Nuts are encouraged in the Dietary Guidelines, and are a potentially valuable addition to most diets (assuming no allergies to them, of course). Walnuts are the pick of the nut crop in my opinion, as well as that of my many colleagues at the Napa meeting. There are likely benefits to weight and health from adding roughly 1 oz of them (seven nuts) to your diet most days.

That, in a nut shell, is the conviction I brought home with me from California. Chew on it as you see fit.


-fin

Dr. David L. Katz; www.davidkatzmd.com
www.turnthetidefoundation.org

 

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I am just back (on the red eye, no less) from the annual Scientific Advisory Committee meeting of the California Walnut Commission held in Napa Valley. If you could live in Napa Valley, why would you...
I am just back (on the red eye, no less) from the annual Scientific Advisory Committee meeting of the California Walnut Commission held in Napa Valley. If you could live in Napa Valley, why would you...
 
 
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HUFFPOST SUPER USER
rawfoodsphd
Rx for Body, Mind & Spirit
04:11 PM on 08/22/2011
Definitely raw walnuts over roasted as the nutrients and enzymes are still intact. In fact, soaking walnuts 12 hours removes the enzyme inhibitants and anti-nutrients from the skin. You can put them on a cookie sheet and let them dry overnight or in sunlight covered with cheesecloth. You can also make a great pate with the soaked walnuts by adding some olive oil, garlic, water and nutritional yeast. The soaked/dried walnuts also taste much better - very buttery and alive. www.rawfusionliving.com
09:34 AM on 08/21/2011
Quite a walnut commercial.

It sounds to me like one thing is measured, endothelial function, then claims of improved blood vessel health implied, and with the inclusion of Type 2 diabetes sounds like this is being suggested as a cure or treatment for diabetes - but all in a rather vague way.

Then eat walnuts and don't gain weight ... sounds like another marketing campaign.

I am all for walnuts, I eat them regularly, and not just in chocolate chip cookies as I used to when I was a kid, but as universal panacea ... I am getting tired of food being treated like football teams in which people cheer and go on about the greatness and superiority of one team over another. ... and at the finish line, there's walnuts first ... almonds coming in a close second with pistachios grabbing third place.

It does seem like a kind of conflict of interest to having people involved in the industry doing studies about the health effects of their products ... just as much as the Wall St. rating firms being paid by the companies they rate. I thought America was so great at using the free market, but we have found all these ways to break it and make it questionable.

Anyway ... back to my walnuts, almonds and cashew snack ... though I guess I may have to drop the cashews for a while until the cashew guy writes a cashew article.
08:32 AM on 08/17/2011
And walnut oil is great on salads.
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11:02 PM on 08/16/2011
Keep in mind that nuts are high in carbs, but still great to add to diets if you keep track of the carbs and don't overeat them. It also wonder if they were talking about black walnuts or english walnuts. This article did not say which kind they were referring to. I am also surprised the article did not list how they compare to pecans, filberts, brazil, and macadamia nuts..
10:28 AM on 08/17/2011
Nuts contain what is known as the good carbs. which you don't have to watch so much as the bad carbs.
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02:35 PM on 08/17/2011
Yes...those are, I think, called ''complex carbs''...and you are right...but you still have to be ''very'' restrained with ''any'' carbs if you have diabetes concerns or are on a low card diet...complex carb or not. Just like , again I think, baked or boiled potatoes are complex carbs...but mashed are not. I still am wondering if it is englsih or black walnuts they are referring to. Where I live, balck walnuts are everywhere...but I don't think I have ever seen an englsih walnut tree.
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HUFFPOST SUPER USER
Freedom Rush
freedom is the oxygen of the soul
10:43 PM on 08/16/2011
are there any pesticide concerns with nuts? i know your exposure would be less if you hulled them yourself, but i was just wondering if anyone had any insight on the pesticide tip.
11:15 PM on 08/21/2011
Peanuts are one of the most pesticide-laden crops out there. Look for organic if you must eat peanuts. There are also concerns with peanut aflatoxin (a byproduct of a fungus that's extremely dangerous.) I'm not aware of the pesticide levels in other nuts - I limit nuts because of the high omega-6 content; only macadamia nuts are worth it to me.
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HUFFPOST SUPER USER
Freedom Rush
freedom is the oxygen of the soul
09:44 AM on 08/22/2011
thanks for the reply tribecca. you've given me a great jumping off point for some research.
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HUFFPOST SUPER USER
johnottr28
NYC The greatest city in the world!
07:49 PM on 08/16/2011
If you could live in Napa Valley, why would you live anywhere else?

Because I live in New York City and there is no better place in the world to live!!!
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indigotrustee
GOP The Party Of Greedy Old People.
07:15 PM on 08/16/2011
The FDA got involved and said walnuts were illegal drugs, because Blue Diamond made
health claims that weren't approved by the FDA.

http://www.dailymail.co.uk/news/article-2018807/Walnuts-DRUGS-FDA-makes-bizarre-claim-seller-says-reduce-risk-heart-disease-cancer.html
05:39 PM on 08/16/2011
Walnut sales must be down.,
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mschultzpa
I don't have to show you any stinkin' badges!
05:08 PM on 08/16/2011
I add them to oatmeal.

Also, I make chicken salad with grapes, apples and walnuts and add just a tiny bit of mayonnaise and applesauce. Some people just use applesauce for health and less calories.

You can also serve the chicken salad on top of a vegetable salad or just romaine.
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HUFFPOST SUPER USER
orbo
Moving Forward!
04:27 PM on 08/16/2011
I love all nuts!
03:29 PM on 08/16/2011
Texas pecans are better for you than California nuts. I mean, California walnuts.
HUFFPOST SUPER USER
sutt202
What ???
04:35 PM on 08/16/2011
I was born in Napa, Ca. and have been eating walnuts from the shell all my life. I'm 70 now and in great shape. Don't know if the walnuts had anything to do with it. But I don't plan to stop eating them.
And Sam, I agree with you. Pecans are the best. Love that pie. They're just to expensive here in California.
HUFFPOST SUPER USER
bmitche
06:32 PM on 08/16/2011
Depends on whom you ask.
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HUFFPOST SUPER USER
Chuck Bluestein
Always searching for latest health breakthrough
04:56 AM on 08/16/2011
I know that the unhulled walnuts that I hull, taste much better than the hulled walnuts. So I would bet that they are healthier also.
04:52 AM on 08/16/2011
Unlike the commenter below me, I think you shouldn't bring the FDA before this at all. I just finished watching a documentary about what FDA really does and how it controls the ingredients in our food - 14,000 ingredients they allow to be precent in our food, and we don't even know how they react to our bodies and what these ingredients are doing to people who are eating them.

Walnuts, when eaten raw is still - just walnuts as an ingredients, much better than any processed ( Healthy so called foods ).

There should be more studies like this, and articles like this, to educate the public about nutrition. Because the FDA sure doesn't a damn about anything but making money from the big companies that pay them.

Thank you for this article by the way.
HUFFPOST SUPER USER
Carolyn Kostopoulos
10:56 PM on 08/15/2011
you might want to bring this before the FDA. they recently smacked walnut growers with a warning letter. according to the cretins at the FDA if you make honest proven claims that food is good for you, it becomes a drug and must come via a doctor's prescription and with instructions. that is unless you are selling "heart healthy" garbage snacks filled with HFCS and other laboratory creations. those manufacturers have obviously paid $$ to the FDA so they get to make the health claims. walnuts do not.

by this type of reasoning, Popeye would be yanked off the air for spinach propaganda and sued by the Beef Association (remember that Whimpy ate burgers) and your mom would be doing time in prison for making unsubstantiated claims about carrots and eyesight!

what kind of country is this where we've outlawed common sense?
04:13 PM on 08/15/2011
While it's true walnuts have a decent supply of Omega 3's, they have a great deal more Omega 6's. I have always heard it was the imbalance in the modern diet - too much Omega 6, too little Omega 3 - that fueled chronic inflammatory diseases. So you would only exacerbate this imbalance by eating a lot of walnuts. So whatever health benefits walnuts confer, it's seems would not be due to the Omega 3 content.

I have also heard (and sometimes observed) that walnuts, once shelled, go rancid quickly. I wish they were obtainable in the shell year round.
06:31 PM on 08/15/2011
Whole walnuts last longer than pieces and can be put in the freezer for about 6 months. I wouldn't have much more than an ounce a day because of what you suggest, as well as the overall fat content that we associate with nuts (though nuts have much more of the 'good' fat as opposed to the bad fat).
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HUFFPOST BLOGGER
David Katz, M.D.
Director, Yale Prevention Research Center; Editor-
06:36 PM on 08/15/2011
Actually, expert opinion is unsettled on this issue- but the weight of evidence seems to favor total amount of omega-3, vs. the ratio per se. I think both may be important. For now, the health benefits of walnuts are clear- and it seems very likely the ALA content is part of the reason.