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David Servan-Schreiber, M.D., Ph.D.

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We Can All Fight Cancer Better

Posted: 02/20/2010 7:19 am

My Story

At age 31, my life took a sudden turn. I was an ambitious physician and neuroscience researcher who reveled in discovery and glittering science projects. Then, slipping into a brain scanner one evening in place of a subject who hadn't shown up, I was suddenly stripped of my white-coat status and thrown into the gray world of patients: That evening, I discovered that I had brain cancer.

Being a physician and scientist is no protection from getting cancer. But it allowed me to dig deeply into the medical and scientific literature to find out everything I could do to help my body resist the disease most efficiently and try to beat the median survival of a few years.

The first thing I learned is that we all carry cancer cells in us. But I also learned we all have natural defenses that generally prevent these cells from turning into an aggressive disease. These include our immune system, the part of our biology that controls and reduces inflammation, and the foods that reduce the growth of new blood vessels needed by developing tumors.

In the West, one out of three people will develop cancer. But two-thirds will not. For these people, their natural defenses will have kept cancer at bay. I understood it would be essential for me to learn how to strengthen these defenses.

A Cancer Epidemic

My own disease is just one case in a cancer epidemic plaguing western societies. Cancer rates have been climbing steadily in the US since 1940. This is not due simply to the increase use of screening tests or the aging of our population: cancer has been rising in children and adolescents at a rate of 1 to 1.5 percent per year in the past 25 years. [1] And cancers that have no screening test (lymphomas, pancreatic and testicular cancers for example) have been increasing as fast or faster than those that do (breast, colon, prostate). [2]

Asian countries did not experience this rise until recently. [3] Yet, Asian immigrants in the US have the same rates of western cancers as Caucasian Americans after one or two generations [4 , 5]

Not a Genetic Lottery

Thus, cancer is not a genetic lottery. A new model has emerged from the last 10 years of research. It moves away from genetics and squarely into life-style factors that we can learn to control.

A New England Journal of Medicine study conducted by the University of Copenhagen showed that people who were adopted at birth had the cancer risk of their adoptive parents rather than that of the parents who gave them their genes [6]. At most, genetic factors contribute 15 percent to our cancer risk. What matters for 85 percent of cancers is what we do -- or do not do enough of -- with our life [3].

Life-style Choices Trump Genes

Indeed, a new Cambridge University study has shown that people who follow simple healthy life-style rules reduce their chances of dying from cardiovascular disease or cancer by roughly a factor of four. [7]

At Ohio State University, another team followed women with breast cancer (stage II) who all had surgery and conventional treatment. Some did not do any more than that, but others participated in an education group focused on better nutrition, more physical activity, and simple relaxations methods such as "progressive muscle relaxation", similar to yoga. Those who learned to change their life-style were 68 percent less likely to die from their cancer in the next 11 years. [8]

Other recent studies -- from the University of San Francisco -- found that such simple life-style changes in men with prostate cancer, completely change the way genes behave, including the genes of cancer cells. This research shows that life-style choices play on our genes like a pianist's fingers play on a keyboard ... transforming the body's ability to resist cancer growth. [9-11]

And in 2009 a stunning reversal of groupthink on the role of genes in breast cancer: Women with the ominous BRCA-1 or 2 genes (80 percent chance of developing breast cancer), reduce their risk by 73 percent if they eat a good variety of vegetables and fruits, showed University of Montreal researchers. [12] Are these really "breast cancer genes" then, as they've been touted to be all along? Or are they simply junk-food intolerance genes?

Changing the "Terrain"

When it comes to treating cancer, there is no alternative to conventional treatments: surgery, chemotherapy, radiotherapy, immunotherapy or, soon, molecular genetics.

However, these treatments target the tumor much like an army wages war: focusing on destroying the cancerous cells. They do not help prevent the disease if we don't have it, and, if we do, they do not help the body build up it's natural resistance to make the treatments work better.

For prevention or better disease management, it is important to change the environment --- the "terrain" -- that supports the growth of new cancer cells, even if treatment pounds them with targeted attacks.

Modern research suggests that cancer cells grow much faster under three circumstances:

1. When our immune system is weakened and less capable of detecting and destroying budding tumors.

2. When low-grade chronic inflammation in our body supports the multiplication of cells and the invasion of neighboring tissue.

3. When tumors are allowed to develop new blood vessels to expand to a larger size, much like a city expands when allowed to develop new roadways.

When we strengthen our immune system, reduce inflammation and reduce the growth of new blood vessel, we help create an anticancer "terrain".

Anticancer Choices

For better prevention, or better treatment results, nothing can beat the combination of conventional medicine (early screenings, or chemotherapy, surgery, radiotherapy, etc.) with an anticancer way of life: A way of living through which we begin to nourish every aspect of health within our bodies:

1. Cleaning up our diet: reducing sugar -- which feeds cancer growth and inflammation. Refined sugar is abundant in desserts, soft drinks (one can of Coke contains 12 coffee-size packs of sugar...), sauces (Ketchup, ready-made salad dressing, etc.), white flour which is equivalent to sugar as far as the body is concerned (white bread, bagels, muffins, etc.), and reducing pro-inflammatory omega-6 fatty acids (red meats, dairy, corn, sunflower, soybean and safflower oils, and trans-fats).

2. Adding anti-cancer foods: including in our diet every day, three times a day, foods that help fight cancer. Such as anticancer herbs and spices (green tea, turmeric, ginger , thyme, rosemary, mint, basil, sage), omega-3 rich foods (salmon, sardines, mackerel, walnuts, green vegetables), cruciferous vegetables (broccoli, cauliflower, cabbage), garlic, onions and leeks, red berries, plums, blueberries for dessert, dark chocolate (more than 70 percent cocoa), and even a little bit of red wine.

3. Engaging in physical activity: it doesn't have to be marathon training, not even jogging. Just rapid walking 30 minutes six times a week already dramatically reduces the chances of a relapse after breast cancer treatment or the risk of advanced prostate cancer. And physical activity has been found to help survival with many different types of cancer. [13]

4. Managing our response to stress: we can't avoid stress in our life, but we can learn to respond differently than with clenched teeth, stone-hard back muscles and pressure in our chest. Basic breathing techniques that have been around as part of oriental mental and physical hygiene techniques for thousands of years (Yoga, Chi Gong, mindfulness meditation) can transform our response to stress and strengthen our resistance to disease. And simply reaching out to one or two friends during hard times can even reduce the risk of dying from breast cancer by a factor of four. [14]

5. Cleaning up our immediate environment: in-door pollutants, parabens and phthalates in cosmetics, scratched Teflon pans, percholorethylene of dry-cleaning, PVCs and bisphenol A from liquids in contact with hard plastics, radiomagnetic fields of prolonged cell phone exposures are the leading and most easily controlled causes.

Conclusion

As a physician with cancer, I've discovered that we can all create an anticancer biology for ourselves through the choices we make in our lives. They cannot replace the benefits of surgery, chemotherapy or radiotherapy, and do not have the same support from aqs many large controlled trials to back them up. However, the life-style changes discussed above are demonstrated to improve health and new scientific evidence suggests they slow down cancer too.

Indeed, as strange as it may seem, I'm in better health and happier today than before I was ever ill. I feel more at peace, lighter, with more energy and drive and passion for life. A few years ago, my neuro-oncologist unwillingly reminded me of the odds against this happening when he told me "I don't if I should tell you this, but I'm always happy to see you at your follow-up visits, because you're one of the very rare patients I have who is doing well!"

Most people who start on this health journey notice a difference within a few weeks. Recent studies suggest that such life-style changes start improving mood and well-being after two to four months, and can have an impact on cancer statistics within a year or two of follow-up. (Andersen et al. 2004, 2008; Blake-Mortimer et al. 1999; Fawzy et al. 1990, 1993; Monti et al. 2006, Spiegel et al. 1989)
What I've learned in my own journey of 17 years with cancer is that the best way to go on living is to nourish life at all levels of my being: through my meals three times a day, through my walks in nature, through the meaning and purpose in my work, through the flow of love in my relationships, and through the protection of our environment. Science told me that this slows down cancer, but, perhaps even more importantly, it brings to my life, every day, a new light and a new purpose.

Dr. Servan-Schreiber wrote the best-selling Anticancer, A New Way of Life.
He regularly posts Anticancer research & insight on his Facebook Page & Twitter Account

Visit Anticancerbook.com for the complete Anticancer Lifestyle Guide

References

1. Steliarova-Foucher, E., et al., Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): an epidemiological study. The Lancet, 2004. 364(9451): p. 2097-2105.

2. Parkin, D., et al., Cancer Incidence in Five Continents, Volumes I to VIII., in IARC CancerBase No. 7. 2005, World Health Organization: Lyon, France.

3. Stewart, B.W. and P. Kleihues, eds. World Cancer Report. 2003, W.H.O IARC Press: Lyon, France.
4. Yatani, R., et al., Trends in frequency of latent prostate carcinoma in Japan from 1965-1979 to 1982-1986. Journal of the National Cancer Institute, 1988. 80(9): p. 683-7.

5. Sasco, A.J., [Migration and cancer]. Revue de Medecine Interne, 1989. 10(4): p. 341-8.

6. Sorensen, T.I.A., et al., Genetic and environmental influences on premature death in adult adoptees. New England Journal of Medicine, 1988. 318: p. 727-32.

7. Khaw, K.-T., et al., Combined Impact of Health Behaviours and Mortality in Men and Women: The EPIC-Norfolk Prospective Population Study. PLoS Medicine, 2008. 5(1): p. e12.

8. Andersen, B.L., et al., Psychologic Intervention Improves Survival for Breast Cancer Patients: A Randomized Clinical Trial. Cancer, 2008. 113: p. 3450-3458.

9. Ornish, D., et al., Increased telomerase activity and comprehensive lifestyle changes: a pilot study. The Lancet Oncology, 2008: p. doi:10.1016/S1470-2045(08)70234-1.

10. Ornish, D., et al., Changes in prostate gene expression in men undergoing an intensive nutrition and lifestyle intervention. Proceedings of the National Academy of Sciences, 2008. 105: p. 8369-8374.

11. Ornish, D., et al., Intensive lifestyle changes may affect the progression of prostate cancer. Journal of Urology, 2005. 174(3): p. 1065-9; discussion 1069-70.

12. Ghadirian, P., et al., Breast cancer risk in relation to the joint effect of BRCA mutations and diet diversity. Breast Cancer Research & Treatment, 2009. 117: p. 417-422.

13. World_Cancer_Research_Fund, Food, Nutrition and the Prevention of Cancer: A Global Perspective, W.C.R.F.a.A.I.f.R.o. Cancer, Editor. 2007, World Cancer Research Fund and American Institute for Research on Cancer: London, UK.

14. Kroenke, C.H., et al., Social networks, social support, and survival after breast cancer diagnosis. Journal of Clinical Oncology, 2006. 24(7): p. 1105-11.

 
 
 

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10:31 AM on 02/24/2010
I'm getting confused. Is soybean good or not good for cancer?
06:45 PM on 02/22/2010
i had lymphoma(non-hodgkins)33yrs.ago, it came about while i was pregnant. i had it diagnosed
6 mos.after delivery.i had it in my left arm-pit and elbo. boston-cancer found no other cancers. i re-
ceived radiation theropy local to the elbow and total body. after that i regained my energy ever soo
slowly. i told my family that i was moving to florida, come with me or stay here. we left and that was
the best, i changed my life style, and did research supplements. unfortunately, my then baby might
have had a tumer (avm)due to my episode. she had a tumer that caused her to have a hystorectomy
at the age of 33. it broke her to have lost her ability to have a natural childbirth. i hope that more
people like the doctor recognize that YOU do make the differrence in your OWN life. GOD and your
doctor do as well, that is what they are there for, for YOU.
04:17 PM on 02/22/2010
Oh, there most certainly are alternatives to chemo, radiation, etc. If you understand the role of endorphins and the immune system you will understand why there are so many success stories with low dose naltrexone. Doctors and researchers all over the US - the world, actually - are using it and TERMINAL pts are being cured. Here, see for yourself:

http://www.lowdosenaltrexone.org/index.htm (just a starter page - go on from there)

If you would take the time, you can find hundreds of people curing themselves of cancer. Yes, it is true. You can find an interview with an MD here and he even has a brain cancer cured with it here: http://www.lowdosenaltrexone.org/gazorpa/interview.html
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Elisabeth Dyer
05:49 PM on 02/22/2010
Thank you.
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jamesinraro
03:16 PM on 02/22/2010
One natural compound that has anti cancer properties is transmax resveratrol. I know because my sister, who was diagnosed with the two worst types of leukemia, recovered using transmax, curcumin and one session of chemo. Her prognosis was very poor and she was scheduled to undergo a round of 6 chem sessions. She started to take 2 transmax each morning and two each evening and underwent the first chemo session. At her followup exam after one month her disease was in solid remission. Hopefully this continues. The oncologists at M.D. Anderson hospital in Houston agree that the resveratrol played an important part in her recovery.
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maidenofdforest
Eclectic Ket
02:37 PM on 02/22/2010
More than halfway thru your books, Dr. Schrieber. The combination of conventional and herbal is really fantastic and the phlethora of information is really very helpful.

Good eats, but make mine healthy!
09:05 AM on 02/22/2010
Thanks doc for this article and for your book -- good work.

But, when it comes to certain cancers (glioblastomas, pancreatic, ..) I disagree with you here: "When it comes to treating cancer, there is no alternative to conventional treatments: surgery, chemotherapy, radiotherapy, immunotherapy or, soon, molecular genetics."

With some cancers, if you DON'T find alternatives, conventional doesn not have much too offer.
01:51 PM on 02/22/2010
Great article. I'll be sharing copies with my nearest and dearest, along with a note that in fact drinking a glass of red wine with meals is one of the best things one can do to help combat cancer and maintain good health. Further details in "Age Gets Better With Wine" by Dr. Richard Baxter, one of my favs as well.
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SEQUOIABISON
President of the Sequoia Bison Society a non profi
08:08 AM on 02/22/2010
Thank you Dr Schreiber for your compelling article. But with all due respect shouldn't you have been putting this type of research into Cancer for your patients? Why did you have to wait until you contracted this disease to look further for answers?

Obviously most reasonable doctors are not satisfied with "conventional" treatment. Chemotherapy and Radiation treatment is very destructive and in my opinion people survive this ordeal despite the treatment not because of the treatment.

I have been a devout vegan for over thirty years and during that time I have not even taken an aspirin. I agree with you entirely that we must build up our immune system to help us combat disease naturally, which has worked very effectively for me.

I believe that only the body has the ability to heal itself when nourished properly and exercised regularly and that drugs and radiation are only an impediment to achieving good health.

Thanks again for sharing your newly discovered research.
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jamesinraro
03:26 PM on 02/22/2010
In defense of Dr. Schreiber you should know that he did put this information in his first book and has been very active in educating oncologists and other physicians in the benefits of diet, alternative treatment strategies and life style-related causes of cancer.
04:46 PM on 02/22/2010
The Dr got cancer at 31, so how much time after med school and a PHD did he "wait"? And how many physicians get cancer and never do this research and share it?? I read anticancer and gave several copies to friends and families. Am grateful for this information. Thank you Dr! Thanks very much.
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Burudika
01:17 AM on 02/22/2010
I am glad to see mainstream medicine start to acknowledge what pioneers like Max Gerson, and others outside Orthodox medicine have known for more than a century! looong way to go but I'm optimistic the public will awaken,
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UltimateLifestyle
12:12 AM on 02/22/2010
This is fascinating. My step-mother has survived two cancers already and has been told that she is genetically predisposed to cancers so I will pass this information onto her to investigate.

Thank you for sharing.
Peace and much love
Lara
http://ultimatelifestyleproject.com
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Javida
10:49 PM on 02/21/2010
Many have successfully overcome cancer w/ nutritition and no medical intervention whatsoever. Brenda Cobb is one such example. She has a nutritiion/cooking center in ATL, The Living Foods Institute. Anthony Satillaro, MD, is another such example. He's authored two books, Recalled By Life and Living Well Naturally. You can google both names.
07:53 AM on 02/22/2010
No..It is very important that the article states that these nutritional changes are IN ADDITITION TO normal cancer treatment. Of course healthy eating and exercise helps. Medicine has been saying this for centuries.

DO NOT treat these reccomendations as a replacement for chemotherapy.
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Elisabeth Dyer
10:43 AM on 02/22/2010
It seems the medical community's insistence on using chemo and radiation will last until people see there are other ways. Chemo and radiation are poison and destruction. You say chemo must be used, I have found you are wrong, but my voice is so small aganist what is excepted as standard.
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Javida
12:49 PM on 02/22/2010
You are apparently totally bought hook, line and sinker to medicine as the critical means for solving health problems. Healthy lifestyles are the critical factor, not medicine, to a healthy longevity. Medicine is required for accidents and emergency care, but not necessarily for cancer or other conditions, such as cardiovascular illness and diabetes.
Cancer, and many other conditions, have been cured successfully by many people with no medical intervention whatsoever.

Both Brenda Cobb and Anthony Satillaro, MD, cured their cancers with changes in diet and both advocate the same. Sure, it's up to the individual to use chemotherapy, radiation, surgery, drugs along w/ healthy lifestyles to treat cancer, but medical interventions in many instances fail to successfully treat cancer. Chemotherapy and radiation kill healthy cells, while killing cancer cells. Drugs often worsen the very condition they're suppose to remedy. Thankfully, diet alone helps many people overcome cancer and other health conditions.
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Good Reason News
05:21 PM on 02/21/2010
I read recently that tests are showing marijuana can effectivly kill brain cancer cells. So, you know, take that how you will.
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jgarma
04:57 PM on 02/21/2010
It's very gratifying to learn that science is underscoring what seems intuitive -- that what goes in you (food, drink, chemicals, even thoughts) will have a decisive influence on your experience of life.

Some studies are now demonstrating that diseases like cancer can be fostered by a series of poor consumption choices linked to compromising our immune systems. Behavior is trumping genetics.

What to do armed with this information? Studies also show that many people will not change behavior even if it's demonstrated that not doing so will sow the seeds of death.

Seems we don't like change.

For those who are ready to act, consider first doing an cleanse and then building yourself up with smart food choices.

More about cleansing here: http://www.garmaonhealth.com/2010/01/detox-time/

And nutritional stuff here... this one from Dr. Oz: http://www.garmaonhealth.com/2010/01/oz-reboot-diet/ ; and this one from me: http://www.garmaonhealth.com/2009/08/diet-101/

Yep.
04:08 PM on 02/21/2010
Love the new book by Dr. Servan-Schreiber - Anti Cancer A New Way Of Life! Fabulous suggestions and life experience. I recently gave it to a friend who was diagnosed with brain cancer - his ideas changed her entire outlook, eating and life.

Another incredible life-changer, as mentioned here by others, is the China Study by T. Colin Campbell. Most people I know who've read it, including highly skeptical physicians, became vegetarians by the time they hit the last page.

Revolutionary research!
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Halsey
"There is a price to pay for speaking the truth. T
12:47 PM on 02/21/2010
I wish I'd read (it hadn't been written yet..so this is theorectical)..The China Study (not cited..but is an amazing eye opener about diet and cancer). when I was younger...I was diagnosed witih Stage IIB, Grade 3 (tumor size HUGE..and literally just showed up overnight)..triple negative breast cancer..no tie in to genes at ALL.. I think of the bologna, canned vegetables, fried pork chops..white bread..I grew up with (every one did back then)...I was always very very healthy...never got colds, flu..nothing.. I did get lyme disease in 2004 (and it took 6 months to find a doctor to properly diagnose and treat)...no one else in my immediate family has or had cancer (and we all ate the same stuff)..I sometimes wonder IF the lyme (combined with a head on collission wherein my chest DID hit the steering column)..maybe triggered what may have remained dormant..into active cancer... any studies on this?
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mssreader
eat, read, sleep, read and be happy
02:41 PM on 02/21/2010
Halsey, glad you mentioned The China Study though not cited in article tis true though Ornish was mentioned in the references. For me The China Study changed my life though I'd already been a veggie since 1969 and vegan since the late 80s, I adopted the plant based diet. It takes a lot of discipline to adopt this healthy diet, or any healthy diet. It just depends upon your reasons for doing so. Most people are ruled by their senses and won't give up burgers and junk food and then when they get sick expect the doctor to make them well. Just reading The China Study is an experience and then buy Eat for Your Life by Doctor Joel Fuhrman who tells you how to implement the plant based diet into your life. I was in good health but now I'm in even better health with no colds, flu or sinus stuff or anything. And I'm very, very slim but a healthy slim. Now it's still a challenge to come up with good foods but there are a lot of good cookbooks out there and you'll soon be doing your own thing. And food becomes less important to you as your health buds change. But you must eat organic whether from organic stores or growing your own. It's worth it!
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Halsey
"There is a price to pay for speaking the truth. T
11:16 PM on 02/21/2010
Thank you Msreader..I am curious..the author was diagnosed at 31..how old is he now?...and..let's get very honest..some women..get breast cancer..it's caught early..small lumpectory..maybe a little radiation (I don't deny..it's still scary)...yet some us of...get hit over the head with a very aggressive cancer that requires the BIG (nasty) guns..multiple surgeries, very toxic chemo (for me ACT) and 30 rounds of radiation..and sadly...no test to see if it's come back (triple negative rarely resurfaces in the breast..rather...goes for brain or bone)...
and I WAS a vegetarian for over 10 years (right not..desperately trying to put ON needed weight..I allow myself some "meat"..and deal with the guilt). I'm still left wondering if the crash and/or lyme triggered a sleeping giant. (but...believe all the research in the China Study).
04:13 PM on 02/21/2010
Dr. Servan-Schreiber sites The China Study in his book with great respect!
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Elisabeth Dyer
04:49 PM on 02/21/2010
I have just ordered the China Study from BN. Free shipping today and the members price. $13.00
12:15 PM on 02/21/2010
The battle against cancer begins in the mouth...what you eat is what you are. Simply as a matter of taste ( I love the taste of really good food; fresh caught lake trout, saddle of venison, fresh baked whole grain bread with local honey, roasted chicken from Helen's farm, fresh sage, mint, thyme, green tea with honey, curried grouse or partridge with basmati rice...I could wax eloquent for pages!).
Eat well, use simple, fresh ingredients (it takes very little to grow your own herbs). Last night's supper; broiled fresh caught lake trout with dill sauce, herbed Yukon Gold potatoes (from our garden),
roasted parsnips and carrots in butter, and rhubarb crisp (from last spring's rhubarb crop, harvested and put in the freezer. Breakfast today...wild blueberry smoothies, with blueberries we picked in August along the Beaver River, fresh whole milk, and real yoghurt. sweetened with a touch of local alphalfa honey Then out for an hour of fresh (and this far north in February, it's very fresh) air, a run with the dog (who is responsible for hunting the grouse). The second best prevention for cancer is to love life. People who truly love their lives don't abuse their bodies by smoking, poor eating, or neglect.
01:12 PM on 03/22/2010
QUOTE-"People who truly love their lives don't abuse their bodies by smoking, poor eating, or neglect.

Hum.. You maybe onto something there..

I'm an American.

Anybody got a cigarette? How about a cheeseburger? Slice of Domino's?

You know, to go along with my 100 hour work weeks, lack of vacation, lack of adequate health care, stagnant wages, over-reliance on financial services, an idiotic and exploitative social and economic environment, dysfunctional government, etc..