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Deepak Chopra

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The Kidneys -- an Overlooked Organ That Can Get Sick, Too

Posted: 11/08/11 08:39 AM ET

The news that America is becoming an obese nation has sunk in to public awareness, and the rise of diabetes and high blood pressure, both exacerbated by being overweight, has also been well-advertised. But there is a hidden danger that gets very little attention: chronic kidney disease (CKD). CKD is the slow loss of kidney function over time. Its prevalence is more alarming than the general public realizes.




Visualization is courtesy of TheVisualMD.com

There are two reasons for this. The first is that the kidneys can function without noticeable symptoms even when they have lost a great deal of function up to 90 percent. The second is that when symptoms do appear, they are diffuse and hard to pinpoint. The most common are


  • Fatigue and weakness

  • Headaches

  • Loss of appetite, nausea

  • Weight loss

  • Dry, itchy skin


How many people suspect a problem with their kidneys when these symptoms appear? Yet CKD is a very common disease. In this country, it affects more than 10 percent of the adult population -- that's more than 20 million people. Of these, more than half a million are being treated for kidney failure, also called end-stage renal disease. By some estimates, low-level kidney disease is the most common disorder among older people that goes undiagnosed.

The reason to bring up America's weight problem is that the two leading causes of CKD are diabetes and hypertension, both of which are often related to obesity. They constitute to two leading causes of CKD when other links, such as urinary obstruction or nephritis -- inflammation of the kidneys -- aren't present. Kidney disease is progressive, starting off at an acute stage and then becoming chronic. The disease is incurable, yet the good news is that losing weight, reducing the risk of diabetes and hypertension, is a good course of prevention.

It's remarkable how our kidneys, which we rarely think about, are connected to the body's overall intelligence. Your kidneys are fist-sized, bean-shaped organs found toward the back of your upper abdomen, tucked under the rib cage. The kidneys' main job is to filter the blood of impurities, but they do a remarkable number of other tasks as well.

First, they filter over 50 gallons of blood per day to remove toxins and metabolic wastes along with excess water while returning needed substances back to the blood. Wastes leave your body when urine is passed. The actual filtering process is nowhere near as simple as, say, the water filtration that keeps drinking water pure.

The functional units of the kidney are its nephrons, extremely fine blood-filtering tubules, about 1-2 inches long. Each kidney contains over a million nephrons. At the end of each is a cluster of tiny capillaries called the glomerulus. In the glomerulus fluid filters out of the blood, leaving behind the red and white corpuscles, and passes through the inner wall of the capsule into the nephron tubule. As it does, specific substances are secreted into it while others, like water, are selectively reabsorbed. The end product is urine.

Why does your blood need filtering? Not just waste is involved. The kidneys perform the vital job of maintaining the body's acid-alkaline balance, called its pH. Blood pH needs to be held in a narrow range, slightly alkaline but close to neutral. The kidneys do this job by providing the blood with a buffer solution that compensates for any rise or fall in the level of acidity or alkalinity caused by diet or stress. This buffer solution contains fluids as well as vital salts, called electrolytes, including sodium, potassium and calcium. In a sense your body is like a car battery, which also depends on electrolytes to produce electrical current. But a battery is static while your body is dynamic. Electrolyte levels of are continually adjusted as needed to maintain pH.

The kidneys also produce hormones, like renin, which helps to control blood pressure, and erythropoietin (EPO), that stimulates the production of red blood cells. Loss of kidney function, then, will be felt in every cell of the body. Because of their delicacy, the capillaries in the glomeruli are vulnerable. The high blood sugar in diabetes are toxic to these capillaries, creating them to develop tiny holes through which toxins can escape. Increased fluid pressure due to hypertension causes the walls of the blood vessels to thicken and the glomeruli lose their ability to filter blood.

The patient may be unaware of any symptoms, but as kidney function declines, along with proper pH and hormone balance, your cells detect the change. Damaged kidneys can't produce enough of the hormone EPO to create an adequate number of red blood cells, for example, and the result is anemia. The heart tries to compensate for this lack by pumping harder. Over time, the heart muscle becomes larger but weaker and starts to pump inefficiently. A damaged heart can no longer pump sufficient amounts of blood to the body's tissues. Edema (fluid waste) begins to back up into the lungs, and it becomes difficult to breathe. The final result is congestive heart failure.

Tests for kidney disease check the blood or urine for substances that are normally missing or found only in minute amounts, such as protein and nitrogen. How well the kidneys are filtering can be estimated by measuring how much of these substances is present. Other CKD tests look for chemical imbalances or anemia.

CKD can't be cured, but it can be prevented, and if caught early on, its progression can be slowed or stopped altogether.

1. Food for CKD

One of the most challenging aspects of having CKD is learning what foods you need to avoid and what you can eat, and in what amounts. As CKD progresses, your kidneys lose the ability to balance electrolytes and to eliminate excess water. For this reason, some foods you probably think of as being healthy, such as certain fruits and vegetables, nuts and legumes, may have to be limited or avoided.

It's extremely helpful to consult with a registered dietitian to create an individualized diet, which should include foods you like as well as nutrients you need.

SALT

Too much salt can cause fluid to build up in your tissues, creating swelling. Avoid foods high in salt, such as many canned foods, salty snacks, cured foods like ham and pickles, luncheon meats, and fast foods. Always check nutrition labels for sodium content.

PHOSPHOROUS

Too much phosphorous in the blood causes levels of calcium to decrease. To compensate, the body starts pulling calcium from the bones, weakening them. High-phosphorous foods include certain (not all) dairy products, organ meats, beans and legumes, nuts and seeds, and sodas.

POTASSIUM

Excess potassium can cause an irregular heartbeat or heart attack. Potassium-rich foods include many fruits (such as avocado, apricots and oranges) and vegetables (including squash, carrots and tomatoes), as well as nuts and seeds.

PROTEIN

Protein digestion creates waste products that the kidneys must dispose of. For people not on dialysis, a low-protein diet can help minimize the amount of protein waste products. People on dialysis, on the other hand, lose muscle tissue. To counteract that loss, they need to eat a high-protein diet that includes lots of meat, fish, and eggs, or vegetable-derived protein.

CARBOHYDRATES

People who are overweight or have diabetes or risk factors for diabetes should limit carbohydrates. Otherwise, they are a good source of energy, as long as you don't overdo it. Desserts made with dairy products, chocolate, nuts, or bananas should be limited.

2. Fluids

Most people who have early-stage CKD can drink plenty of fluids. But as kidney disease progresses, the kidneys become unable to remove enough water from the bloodstream. Fluid builds up in the body, blood volume increases and the heart becomes overworked.

Tell your doctor if you are producing either more or less urine than you used to, if you have any swelling in your extremities or abdomen, or if the skin around your eyes is getting puffy.

3. Exercise

Loss of muscle tissue, fatigue, weakened bones, and lack of appetite are some of the worst side effects of CKD. Exercise can prevent or modify these side effects.

Aerobic exercise is physical activity, such as a brisk walk, that raises your heart beat and respiration rates over an extended period of time. Aerobic exercise strengthens your heart, lowers blood sugar levels, improves your appetite and gives you more stamina.

Anerobic exercise is short-term activity that uses up oxygen very quickly, such as weight training. Anerobic exercise builds up muscle tissue and counteracts the loss of muscle that often accompanies CKD. It can help to boost bone density as well.

It's especially beneficial to combine aerobic exercise with anerobic exercise, because building up your muscles helps you to perform both everyday activities and aerobic exercise better.

4. Other lifestyle measures

Weight loss

Taking off even modest amounts of excess weight can help to protect your kidneys. Losing as little as 10 lbs. can lower blood pressure. Losing 5-10 percent of body weight significantly reduces blood sugar levels. Plus, being at a normal weight lowers the strain on your heart and allows it to pump more easily and efficiently.

Smoking cessation

Smoking fills your kidneys with toxic heavy metals, including cadmium and lead, and damages all your blood vessels, large and small.

Stress management

Unmanaged stress raises blood pressure and damages blood vessels. Find ways to unwind if you're chronically stressed.

Because alert management works for many people, and since CKD is associated with diabetes and hypertension, two disorders that need to be prevented for many other reasons, most of us shouldn't focus on our kidneys directly. End-stage treatments, which involves dialysis or even a kidney transplant, are extreme cases. The main reason I bring up CKD is that it is too often overlooked in older people and secondly, because the more we know about the body's astonishing interwoven intelligence, the more true it is that prevention is vitally necessary for good health over the long lifetime that most of us are anticipating.

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The news that America is becoming an obese nation has sunk in to public awareness, and the rise of diabetes and high blood pressure, both exacerbated by being overweight, has also been well-advertised...
The news that America is becoming an obese nation has sunk in to public awareness, and the rise of diabetes and high blood pressure, both exacerbated by being overweight, has also been well-advertised...
 
 
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05:19 PM on 11/18/2011
Getting enough water is a major issue in many health problems.
05:01 PM on 11/14/2011
Everyone pees.

Simplified.
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Hollye Harrington Jacobs
www.TheSilverPen.com
09:39 PM on 11/10/2011
I have a 45 year old friend who until March was an incredibly healthy and vivacious woman. This spring, she was diagnosed with a rare form of Stage IV kidney cancer. In 6 short months, the cancer has spread to virtually every organ, including brain, lungs, and bones. She had absolutely no symptoms and was healthy and thin. The kidneys are indeed very important organs.
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drvittoriarepetto
03:20 PM on 11/09/2011
I've seen research papers talking about how Vitamin D helps people w/ CKD..get your 25 Vitamin D status checked
01:21 AM on 11/09/2011
Ever since, and prior to, my kidney transplant, I followed my Nephrologist's food guidelines and put off dialysis for about 10 years! Eventually, I did have a transplant (which is doing very well) and I still watch what I eat! This summer I was eating LOTS of honey dew melon - they were excellent, only to find out my Potassium level was quite elevated! Culprit = Honey Dew Melon - they are very high in Potassium. Unfortunately, most labels on food products don't include the Potassium content and they should. To quote from the article:
"Excess potassium can cause an irregular heartbeat or heart attack. Potassium-rich foods include many fruits (such as avocado, apricots and oranges) and vegetables (including squash, carrots and tomatoes), as well as nuts and seeds." In all innocence I thought i was eating healthy food. I was, but just not in moderation!
Biggest thing I reduced was Sodium. It is a catch 22 spice. Have you ever watched a chef on TV say, "and I add a pinch of salt" which looks more like about 3 tablespoons!
Oh, well, just be careful, read labels, try to limit salt...difficult, but it can be done....IF you want to!
10:17 AM on 11/09/2011
Congratulations on your kidney transplant. My husband got his more than a decade ago.

I made a list of all of my husband's medications (including dosage and when he takes his medications). I also wrote down telephone numbers to contact me, his nephrologist, and his job. I also wrote down when and where he had his kidney transplant. He carries this piece of paper on him at all times. This is just in case he is involved in some accident, and it will give the paramedics information about my husband's condition and medications.

My husband also carries 1 full day of medications on him at all times. He takes public transportation to and from work. Sometimes, the trains are canceled or delayed. I never want him to be stuck somewhere without his medications. You know how the transplant centers drill it into your head that (as a transplant patient) you cannot miss 1 dosage of your medications.
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bmitche
12:08 AM on 11/09/2011
Cutting back on salt can be trying. Everything has salt, even bread; however, some health food stores carry bread that is salt free. The price runs about $5.00 per loaf. Canned goods are loaded with salt.
09:57 AM on 11/09/2011
It really isn't difficult once you get used to reading labels. You don't have to go to a health food store. Just spend a little more time comparing the sodium count on the labels at your regular grocery store. Del Monte has low sodium and no sodium canned vegetables. Look into frozen vegetables (without the sauce), which has alot less sodium than canned vegetables. I prefer fresh vegetables over frozen, and frozen over canned.
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Chuck Bluestein
Always searching for latest health breakthrough
03:02 PM on 11/08/2011
Everyone would do better with less salt. Webmd.com has an article saying that cutting salt is as good as quitting smoking. This means that salt is worse than smoking. It did not say that cutting down on smoking is as good as quitting eating salt. Salt is not a food. You can get enough sodium from foods. Salt makes you drink more liquids causing your kidneys to work even harder than they do.

Also many pounds of excess weight is caused from retained water due to salt. So cutting down on salt causes you to lose excess water weight that you do not need. http://bit.ly/mZ18RQ Other than salt, smoking is known as the worst thing for health. That is why they want to put graphic pictures on the packs of cigarettes that I read that a judge has blocked for now.
10:14 PM on 11/08/2011
I agree. People should also read the labels on the food packages. 125 mg per serving is considered low sodium. Too many food products contain high sodium. Stay away from high sodium food products.

Years ago, when my husband was diagnosed with kidney failure, I stopped cooking with salt and pepper. I use fresh or dried herbs to season the dishes. I read the labels on food products to check the sodium content, and I only buy no salt or low salt items. When family and friends come to eat, no one notices the missing salt or pepper.
10:38 PM on 11/08/2011
Excellent comments....Would you please pass the salt?
10:40 PM on 11/08/2011
Why did you stop using pepper?
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02:28 PM on 11/08/2011
Good article. Well worth reading. Thanks!