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Antibiotic Resistance: One Mother's Fight

Posted: 05/08/11 11:13 AM ET

My beautiful, curly reddish-haired cherub of a boy, Simon, is dead. As short and cold as that sentence feels, that is how it happened. Hearty and healthy at one-and-a-half years of age, one spring morning seven years ago, Simon woke not feeling well. By afternoon, his face was cold and his breathing was labored. At nightfall he was bloated, covered in purple splotches and went into septic shock. The drugs Simon received failed, and he never woke up again. I need not delve into the feelings of desperate, painful insanity that I felt, and still feel, about this unfathomable experience. It is a parent's worst nightmare.

It is not possible for me to "wake up" from this nightmare. But we as a society must wake up and prevent other nightmares from occurring by preserving the efficacy of our antibiotics.

At the time of Simon's death, no one -- really, no one, including the highly competent University of Chicago health care providers -- knew why Simon had died. We learned only after an autopsy that Simon had contracted an antibiotic-resistant bacterium called, MRSA, or methicillin-resistant Staphylococcus aureus. And, it was the relatively new community-associated MRSA strain, not the more commonly known health care-associated strain. You're asking, "What is that?" That is what my husband and I (two Ph.D.-level professionals, mine in public health) asked as well. My husband and I racked our brains, endlessly wondering what we could have done to prevent Simon's death. To this day I do not know how Simon contracted this bug and why he was susceptible to it.

If someone had asked me, before Simon died, what I would do if I lost a child, I know that I would have responded something to the effect of not being able to go on with life. To my astonishment, people that I have met and would not have met if Simon had not died, such as other parents who lost children and a slew of health care and media folks, have somehow kept me afloat by validating my feeling that losing a child should not be allowed by the laws of nature. Others at the University of Chicago helped me focus on a bigger cause and made it possible to found the MRSA Research Center. The Center's mission is to understand and interrupt MRSA transmission through basic scientific and clinical research. We still do not know basic things like how MRSA is spread and why some people get sick from MRSA and others do not.

My personal goal at the MRSA Research Center is to make the term MRSA as familiar as AIDS and, most importantly, to raise awareness about the cause of the current MRSA epidemic: antibiotic resistance. Frequent, low doses of antibiotics not strong enough to kill all bacteria encourage some bacteria to develop means of survival or to become resistant. This results in stronger infections. Because of our society's overuse and misuse of antibiotics, we have created a perfect storm for such superbugs to thrive and wreak havoc. The more antibiotics we use and the more we use them improperly, the more bacteria evolve and become resistant -- slowly but surely rendering entire classes of wonder drugs useless.

I have always known that we are doing what we can at the MRSA Research Center, but I know that we are just addressing the tip of the iceberg -- 70 percent of antibiotics sold in the United States are given to healthy food animals, not people. Animals do not receive antibiotics the way humans do. Antibiotics are a regular feed supplement intended to increase growth and lessen the chance of infection in crowded, industrial farms. Antibiotics dispensed in this manner simply encourage bacteria to mutate. That is why a number of the "superbugs" like MRSA are showing up in food animals and industrial farms.

It is my strong personal and professional opinion that we have no choice but to regulate the largely unregulated use of antibiotics in food animals. Agribusiness is composed of people, people with families, parents with children. These people must know that it is in their own best interest to eliminate the routine use of antibiotics (the same antibiotics used to treat people) to promote growth in food animals.

There is something you can do to help honor Simon, and make sure that other mothers don't face the pain of losing a child to a malicious bacteria. Please join the new group, Moms for Antibiotic Awareness -- an initiative of the Pew Campaign on Human Health and Industrial Farming. We are working to raise awareness across the country on the routine use of antibiotics in food animal production and to engage moms and those concerned about their family's health to take action for more judicious use of these drugs. We are encouraging passage of legislation or regulation that would put an end to the misuse and overuse of antibiotics in food animal production. We also are asking restaurants, supermarkets and other food providers to offer more meat and poultry raised without the non-therapeutic use of these life-saving drugs.

We used to call my son, "sol" ("sun" in Spanish), and daughter, "luna" ("moon" in Spanish). When Simon died, I believed my sun would not rise again. What I did not realize is that Simon would keep giving me the gift of sunshine, every day, translated into hope that his life and death will serve as a catalyst for major and positive change. But I can't do this alone. I hope the ray of Simon's sun that shines on you motivates you to work together in our outrage at the mere thought that other children can suffer a demise similar to Simon's. We all created the problem. We now are all responsible for correcting it. Join the Moms for Antibiotic Awareness campaign at SaveAntibiotics.org and let's work together to keep these drugs working for every family.

 
My beautiful, curly reddish-haired cherub of a boy, Simon, is dead. As short and cold as that sentence feels, that is how it happened. Hearty and healthy at one-and-a-half years of age, one spring mo...
My beautiful, curly reddish-haired cherub of a boy, Simon, is dead. As short and cold as that sentence feels, that is how it happened. Hearty and healthy at one-and-a-half years of age, one spring mo...
 
 
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HUFFPOST SUPER USER
Seven Teenatheart
Tolerance, peace, and sanity. Be your own person.
11:33 PM on 05/09/2011
Deepest condolences to you for your unfathomable loss.
HUFFPOST SUPER USER
ddanimal
03:45 PM on 05/09/2011
The Meatrix:

http://www.youtube.com/watch?v=rEkc70ztOrc
02:10 PM on 05/09/2011
my very deepest condolences on the death of your son. i lost my 22 year old daughter five years ago and am only now starting to return to any type of 'normal' activity. i applaud your strength and compassion in this journey to share the dangers of mrca with others. thanks.
HUFFPOST SUPER USER
anothersarah
11:26 AM on 05/09/2011
As a mother and an RN with 31 years of maternal-child nursing experience, I am so sorry for the loss of your son. There are no words.
Every summer I go with our church youth group to visit a church we sponsor in rural Jamaica. Twice a day we visit their nursing home (you can only imagine the conditions of a nursing home in a third-world country!), and last year found the state of those patients worse than usual. We always use hand-sanitizer as soon as we leave the grounds, as there is no hot water for a good hand-scubbing. Last year I broke out with painful boils all over my body as soon as I got home, and before I could get to the doctor I was running a fever and vomiting. She had to lance and drain the sores (you cannot imagine how painful!). They tested positive for MRSA, and I was immediatly put on a strong antibiotic.
This year I am taking a tube of bacitracin ointment to put in the nasal passages of everyone and a bottle of Hibiclens - we will use that and cold water and scrub brushes!
02:28 PM on 05/09/2011
what a wonderful person you must be to donate your time and your heart. cheers!
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HUFFPOST COMMUNITY MODERATOR
moonflowerjewelry
Buy American made, no excuses.
10:00 AM on 05/09/2011
My condolences for your devastating loss, my heart is with you.

Part of your article should have been about what to do about MRSA in your environment... months ago I read a piece right here on hp - the most "revolutionary" way to combat MRSA is to wash with a ph-balanced soap (not triclosan, not commercial detergents disguised as soaps) but your run of the mill hand made cold processed vegetable based soap (my farmer's market has a gal who makes it, etsy has a gazillion cottage industries that make soap here in the US).
Japan has the highest rates of horrific MRSA infections, and they are the most scrupulous in using chemical anti-microbials. Hospitals that clean with ph-balanced soaps have the lowest rates. Remember the phrase shoved down our throats in the 50s, 60s & 70s: "better living through chemicals"?
Stop feeling so powerless, people. Avoid factory farmed meat, get rid of the chemical cleansers (use vinegar, oil soaps, lavender water) - those few things will reduce your risk. But see, only the people who read my post will know that, as opposed to everyone who merely read the article.
08:21 AM on 05/09/2011
I've had several loved ones suffer with multiple drug-resistant infections in the last ten years. Both survived, but only barely.

One caught a drug-resistant staph infection in her bloodstream within hours after she had an outpatient angioplasty. The infection caused her lungs to stop working. The drugs they gave her to treat her lungs got together with the Cumadin they gave her post-heart procedure, she had internal bleeding, and the bleeding on her brain nearly killed her. She suffered with brain damage for years and never has fully recovered. I think that angioplasty ultimately wasn't worth it.

If I have to go to the doctor's office, I am extremely careful about touching things and washing my hands as soon as I get back in my car. I don't even like to visit people in a hospital. Both are veritable repositories of germs.

These places OUGHT to be scrubbed thoroughly every day. They OUGHT to smell like hospitals used to smell---of phenol. But they aren't.

Even though they may look clean enough, the examining paper changed between patients, and the tips of instruments either disposable or autoclaved, staff washes hands and/or uses gloves, the commonly touched surfaces are rarely cleaned. Doorknobs, walls, handles, elevator buttons, writing pens, chair arms, magazines, toys...all teeming with pathogens. All filthy.

Stay away from these places, people, if you possibly can.

Yet another reason to exercise, not smoke, and watch what you eat...
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alongst
too often denied to speak
08:40 AM on 05/09/2011
Yet you can catch MRSA from day cares, nursing homes, restaurants , toilet seats ( yes, really), movie theaters, etc.... MRSA can survive on plastic surfaces for up to two weeks.
Now, try to avoid all of those places as well.
HUFFPOST SUPER USER
b525
06:21 AM on 05/09/2011
Much of the current plague of antibiotic resistant bacteria can be traced to the overcrowding of animals on factory farm operations.

These animals are crowded so closely together that they are forced to cough, sneeze, vomit, urinate, bleed, defecate, attack and wound one another while breathing in ammonia filled air caused by standing in their own waste all day. This ammonia filled air burns away their mucus membranes causing increased respiratory infection rates.

This overcrowding and waste forces farmers to heavily drug these birds with antibiotics to stop disease spread in these unsanitary and overcrowded conditions.

Sometimes hundreds of thousands of birds can be crowded into one enormous barn/operation. Pigs are also overcrowded like this in factory farm operations.

The way to fight this animal and drug abuse is to support free range/organic farming which allows animals to forage in pasture for feed and behave normally.
06:14 AM on 05/09/2011
I am so sorry for your loss :( From what I understand, MRSA uses protective measures against antibiotics in terms of the biofilm development which the efflux pumps play a key role. I have read that they have begun to develop drugs that stop the efflux pumps - hence more susceptibility to abx. I also understand that certain plants (herbs) will assist the abx in working better. I have been dealing with a resistant organism and have compiled a database of relevant articles at pptu.lefora under the category of biofilms.
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NoMoreDrama
Less Obstruction, more Construction!
04:23 AM on 05/09/2011
I'm very sorry for your loss. I have been studying bacteria and viruses for 7 years now as it relates to a technology that I have been working with in that time. It would be shameless of me to promote what I think is a good alternative to antibiotics in this context, but its not the whole reason that I won't. Having invested so much time and energy trying to introduce people to a hard science based, non-toxic disinfectant/sterilant and encountering nothing but obstacles at every turn, I am weary. If you were able to bathe Simon in a non toxic oxidant that would destroy MRSA without harming sensitive tissues, he might have had more time or be alive today. I'm very tired of big pharma being the be all end all while emerging technologies have to bob and weave through the maze of regulation created by Big Corps to stamp out competition. In a nutshell, a weak saline solution stripped of its electrons looks to regain those electrons. When it encounters single celled organisms it oxidizes them without harming healthy human tissue. I use this solution everyday in hydroponics, daily cleaning, vet care for my dogs, hygiene for myself. I haven't been sick or had the common cold in 6 years since I started using it extensively. I've tried to tell so many people about it and show them all it can do, but Pine and Lemon scent is more reassuring than an 8 log reduction.
07:55 AM on 05/09/2011
Can I make this saline solution at home, NMD?
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NoMoreDrama
Less Obstruction, more Construction!
05:38 AM on 05/21/2011
I can make the saline solution at home, I have invested in the equipment. I could give you some of it if you are interested. Not sure how to talk directly to people on Huffpost.
HUFFPOST SUPER USER
quidam56
02:41 AM on 05/09/2011
Well, in Virginia and Tennessee and according to Wellmont Health Care Systems, MRSA is deemed, defended and supported as acceptable standards of health care. Beware if you live in East TN or SWVA, stay away from filthy Wellmont facilities ! www.wisecountyissues.com/?p=62
MommyMD
MD, Professor, Mom
02:33 AM on 05/09/2011
I send you much love and strength for what is to me unimaginable.
I would like to add:
1. I agree with William Hunter Duncan below regarding decreasing subsidies over regulation reg. farm animals
2. MRSA is EVERYWHERE...at my hospital all pt.'s are swabbed routinely and many, many are carriers. I am afraid the horse is out of the barn on MRSA...we best develop more antibiotics to clean up this bug and use governement precaution to prevent the future superbugs.
3. I have found a useful precaution is to NEVER EVER trust health clubs as "clean" environments. I Shared yoga mats and gym equipment are teeming with MRSA.
4. Because MRSA is truly everywhere, you, and all of the other sufferers (myself included) did nothing to precipitate this horrid illness (Although I'm sure you know that).
Thank you for a thoughtful article. I hope your life has mended in whatever way possible.
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HUFFPOST SUPER USER
bkerensa
BenjaminKerensa.com
02:23 AM on 05/09/2011
I don't think telling people to use restraint when it comes to anti-biotics is a good idea. If your doctor prescribes an anti-biotic you should take it. MRSA is no new thing and every doctor in the U.S. is educated and trained on it.

I was speaking with a Dermatologist just months ago and he explained his irritation in the research community and government for not funding much research on MRSA even though it kills plenty of people every year. MRSA is almost always on every person it likes to live in the nasal passages so if you touch your nose your often spreading it around the body and then when a sore, pimple, scratch or rash gets any contact with MRSA then you have problems.
HUFFPOST SUPER USER
Jim Pasterczyk
Banned!
02:14 AM on 05/09/2011
Thanks to agribusiness for strengthening the resistance of so many pathogens by routinely adding antibiotics to animal feed for the sake of getting the livestock to market weight sooner.
12:07 AM on 05/09/2011
Very important piece. Everly, I am so sorry for your loss. Thank you for turning this unspeakable pain into life-saving work. So you know, I tried to follow the embedded link above to the facebook page and from Pew's site too and it says "page not found." I'll keep checking back until it does work and will let all my friends know too. Thank you and God speed.
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10:59 PM on 05/08/2011
With sincere respect for your loss, I must say, regulation will not work. Only ending Agricultural subsidies and ending antibiotic use for feed animals will prevent the creation of such superbugs.

www.offthegridmpls.blogspot.com