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George Vradenburg

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Funding A Cure For Alzheimer's: How It Could Save America Billions

Posted: 10/01/11 03:19 AM ET

While the congressional super committee meets in Washington in the hopes of lowering spending by about $1.4 trillion over the next 10 years, here's one of the sobering realities they must face: In that same decade, the nation will spend an additional $2 trillion caring for Americans with Alzheimer's.

The cost of this care -- primarily in Medicare and Medicaid payments -- will negate virtually all of the gains made from the Budget Control Act of 2011. For the health of our nation's economy and seniors, we cannot accept this two-steps-forward, two-steps-back approach.

To achieve real and lasting savings, the super committee must recommend more funding for Alzheimer's research for the new treatments that will produce massive savings to the Federal government in the next 10 years.

Despite the overwhelming evidence of a growing health crisis and price tag, the National Institutes of Health only invests about $450 million per year researching cures and treatments of Alzheimer's. By contrast, it annually invests $5.8 billion on cancer and $3.1 billion on HIV. Cancer and HIV/AIDS death rates are declining and Alzheimer's death rates are up dramatically. This lack of urgency explains why, among the nation's 10 leading causes of death, Alzheimer's is the only disease with no known treatment or cure.

As we gear up for the 17th World Alzheimer's Day next week, 5.4 million Americans suffer from Alzheimer's disease. Last year alone, Alzheimer's cost taxpayers $183 billion.

As baby boomers turn 65 this year at the rate of 10,000 per day, one in eight of them will have Alzheimer's and 10 million of them will die with this disease. This baby boomer class includes notably spry Americans like Dolly Parton, Steven Spielberg and both Presidents George W Bush and Bill Clinton.

Perhaps the reason curing Alzheimer's is not a top-of-mind issue is because it's not pleasant to think about. For many of us, there is no greater fear than losing a lifetime of memories.

Another reason some aren't as concerned about Alzheimer's is because they see the effects of the disease as a normal function of aging. But from personal experience, I can say there is nothing normal about Alzheimer's.

Twenty years ago, my wife's mother called at 3 a.m. to complain about a strange man in her house. We rushed over, only to find that the "strange man" was my father. By the end of her life, my wife's mother could no longer speak, move or recognize her daughter. This lioness of a woman disappeared into the unforgiving chasm of Alzheimer's.

We can change this devastating fate for other Americans and for the future of our heavy economy.

The research community believes a cure for Alzheimer's is possible within 10 years with the right plan adequately funded. Ten years may seem challenging -- and it is -- but let's not forget President John Kennedy's challenge in 1961 to land a man on the moon before the decade was out. Apollo 11 touched down on the moon just eight years later. It's time for another giant leap for mankind.

As Jonas Salk said before discovering a vaccine for polio, "We don't need more iron lungs, we need a cure." Today, we don't need more nursing homes, we need a cure. Alzheimer's is bankrupting our nation. In this era of budget austerity, we cannot afford anything less than a cure.

 
While the congressional super committee meets in Washington in the hopes of lowering spending by about $1.4 trillion over the next 10 years, here's one of the sobering realities they must face: In tha...
While the congressional super committee meets in Washington in the hopes of lowering spending by about $1.4 trillion over the next 10 years, here's one of the sobering realities they must face: In tha...
 
 
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Debbie338
What we manifest is before us
12:13 PM on 10/09/2011
A lot of people seem to be blaming pharmaceutical companies for not finding a "cure." But, we already know that the typical American lifestyle of bad food and no exercise underpins the risk factors for Alzheimer's. Americans don't want a solution that requires them to work at it, like changing the way they do things. Americans want a magic pill.
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SHIRLEY CARR
optimist with experience sez
07:21 PM on 10/06/2011
What memories I have now have been zapped by a stroke. While I believe in cures for everything, I also believe in letting go when it's your time. As I now live on the edge of my demise.....
04:56 AM on 10/06/2011
Important and valid points in this article regarding the need for more Alzheimer’s funding; the very fact that some may view this disease as a part of natural aging demonstrates a huge gap in understanding in light of the statistics. What is often overlooked is the importance of participating in clinical research trials if the opportunity ever presents. Nothing is more powerful than research and links to cost for policy makers. We need funding for more research to get one step closer to understanding the underlying cause of Alzheimer’s – that is what will change everything for everyone.

Steven East, CEO and President
Caring People Home Healthcare Agency Servicing New York, New Jersey and Florida
http://www.caringpeopleinc.com
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Sharon Hanson
Skeptical of the *pseudo-skeptics*
11:08 PM on 10/04/2011
You know I am so tired of reading these diatribes about how there is no money and no cure and if and if and if only. When are we going to wake up to the fact that big pharma wants us sick from cradle to grave. They don't care about cures or the why as long as they can pump us full of drugs and scan us to death. And speaking of scans, do you think injecting a toxic heavy metal to the tune of over 300M doses would cause any mental impairment or disease? They continue to do MRIs with gadolinium based contrasting agents on MS patients and kids with autism even though it is known that MS patients are more susceptable to developing a not so rare disease called Nephrogenic Systemic Fibrosis.
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Ranveig Elvebakk
Innovator, author and lecturer on weight and nutri
05:32 PM on 10/04/2011
As I said, we need treatment for the unfortunate patients who have Alzheimer's, but we won't find a "cure' for Alzheimer's any more than we have found a cure for any chronic disease. For a simple reason: Chronic illnesses are inflammatory processes and have source-causes. Putting a band aid on the process downstream or at the end organ symptom does not stop the inflammatory process Until we accept that, we will get nowhere. On the other hand, we will find prevention if we look in our back yard. Alzheimer's is prevented the same way as is the rest of them: with anti-inflammatory measures, starting with diet -
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Sharon Hanson
Skeptical of the *pseudo-skeptics*
11:18 PM on 10/04/2011
Wow great comment. You might be interested in knowing that MRIs with gadolinium based contrasting agents are causing a new man-made disease called Nephrogenic Systemic Fibrosis but which should be called gadolinium associated systemic fibrosis. Gadolinium is a toxic heavy metal they have injected into the patient population over 300M times. It stays in the body at a rate of at least 1%, is found in the brain tumors of those with normal functioning kidneys and in the reproductive organs of women of childbearing years.
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DrP
10:35 PM on 10/03/2011
We need research into more lifestyle changes to treat health conditions, not more pharmaceutical solutions.
12:27 AM on 10/06/2011
Yes, but if the answer is not found to be in a Big Mac or KFC it will likely be ignored by the general populace.
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DrP
10:31 PM on 10/03/2011
The research using very low-carb, high-fat, ketogenic diets for Alzheimer's are very promising and compelling, and make sense scientifically. Insulin-resistance certainly must affect brain cells, so fueling the brain with ketones is logical. I hope to see more research into the insulin/neurological disease connection.
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rodjard
I Update my brain frequently
11:27 AM on 10/03/2011
If we are putting Aluminum in food, bread and baking powder
and bromide and fluoride are not completely outlawed, then
all research is just another corporate funded lie.
GET SERIOUS!!!
heckmepitus
Truth, justice and the American way
12:26 AM on 10/03/2011
LOL, you got one example that was so stupid and exceptional that made the news.
Do you realize how many people go bankrupt in the US because of medical costs? More than t 700,000 a year and that doesn't count the 45,000 people who die yearly because of lack of insurance.
http://www.reuters.com/article/2009/09/17/us-usa-healthcare-deaths-idUSTRE58G6W520090917
http://articles.cnn.com/2009-06-05/health/bankruptcy.medical.bills_1_medical-bills-bankruptcies-health-insurance?_s=PM:HEALTH
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DrP
10:32 PM on 10/03/2011
"Obamacare" is not socialized medicine. Please do some research.
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Sharon Hanson
Skeptical of the *pseudo-skeptics*
11:12 PM on 10/04/2011
Corporations control socialized medicine too.
02:20 PM on 10/02/2011
While it is too late for my Mother, I feel that all of this GOP TPer and JBSer Meadown Muffins is all about taking so much necessary Money/Funding away from the Government, that Research will be
compromised to the point that 10 years is a pipe dream and 30 a reality.

Which becomes an even bigger tragedy because of the higher number of persons affected and the
costs involved.
02:12 PM on 10/02/2011
there was a study that suggests ingesting cannabis can help Alzheimers.

http://www.dailymail.co.uk/health/article-530252/Scientists-claim-cannabis-offer-hope-Alzheimers-sufferers.html
05:44 PM on 10/02/2011
Sure, that makes sense. If there's one thing pot heads are known for it's their mental clarity and their keen ability to remember stuff.
08:15 PM on 10/02/2011
yeah its not the obvious drug of choice for this ailment
12:27 AM on 10/03/2011
It is worth the try..
01:25 PM on 10/02/2011
If we ever get a real cure for Alzheimer's disease it will have to come from pure research or another country. Big pharma in the US sees that there is far more money in "treating" Alzheimer's than in really finding a cure. Face it. Our healthcare is soooo broken because our government allows our providers to gouge the US populations while subsidizing drugs to third world countries. If it doesn't make big bucks here... it's a waste of time 'cause we are the only ones paying a premium on drugs.
03:33 PM on 10/02/2011
Bingo.

As long as there is more money to be made in treating diseases like AIDS and Alzheimers, there will be no cures. Big Pharma is one of the major controlling corporate arms of this government, and that is not likely to change. Unless perhaps some of the tools at the top actually get the diseases - hey, I can dream.
04:50 PM on 10/02/2011
That's ridiculous. Any drug that could stop or slow down the progression of Alzheimer's disease would almost assuredly be a blockbuster. A search of the word "alzheimer" on the clinicaltrials.gov website shows 972 results, so it's not like they're not looking for a way to treat it.

Remember it's not an infectious disease like smallpox or AIDS- there is no hope of it being eradicated. So being able to treat it or halt its progression would be plenty profitable to the pharmaceutical companies, especially as the population of developed nations grows older. There's a chance that discoveries of lifestyle factors contributing to the onset of the disease would reduce the number of people who develop it, but that usually has a minor impact on the numbers, unless it was something as simple as washing hands or taking a supplement.

I do agree with you on the cost of medicine in the US. I have no objection to subsidizing the cost for third world countries, but it's ridiculous that we're paying 5-10x as much as other industrialized countries. It's largely due to a "let the insurance companies pay for it" attitude, but they stick it right back to us with $1000 monthly premiums. We make up less than 5% of the world population and pay ½ of the total pharmaceutical cost. The EU, UK, Canada and Japan (just to name a few) should be paying a little more to help offset the burden on the US.
07:18 PM on 10/02/2011
Actually there is a LOT of money being made on "treatment" drugs for AD. Namenda, Aricept, Exelon, Cognex, Razadyne... then there are meds to treat the agitation all the way up to antipsychotics for the really agressive behaviors. Meds to treat the sleeplessness, meds to treat the urinary tract infections and the bowel movement issues. With Alzheimer's Disease you never know what areas of the brain (which controls even the breathing) will be affected since it can affect any part of the brain on any patient. Then meds to treat side effects from other meds (constipation, dizziness and possibly headaches, and [more] confusion, nausea etc). The OTC meds for swallowing issues including special thickeners for liquid diets. And we can't forget the extra medical tests to monitor potential side effects to organs such as the liver.

None of the above even scratches the surface of the cost of the OTC meds, medical supplies and medical equipment... which keeps the entire medical industry going.

And Alzheimer's can show signs as far out as 20 years before death, however usually it's "caught" about 10 years out. Still 10 years of thousands and thousands of dollars on meds a year... Cure be damned! The longer we go without a cure the more millions Big Pharma makes.
07:18 PM on 10/02/2011
Not ridiculous at all. A drug that would "slow down" the progression would be ok with Big Pharmaa, as people would be on it for decades. In fact, there are already such drugs (e.g. Aricept, Namenda, etc.) and they are hugely profitable primarily because people buy them for years and years.

A drug that would "stop" the progression, on the other hand, would clearly be a one shot inflow of revenue, and that would never satisfy the greedy corporate slugs who own the drug companies.
HopeWFaith
We the People
12:22 PM on 10/02/2011
In total agreement with you. Thanks for the article.
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Pelican1983
Eat your peas!
07:57 AM on 10/02/2011
I agree that a cure would be the best case-scenario, but I'd prefer to see more funding go toward diseases that affect younger people, so that they can have a full life like the Alzhemer's sufferers have had.

Also, when you say, "cure," I'm thinking you mean expensive medication daily until end of life, thereby controlling chronic symptoms.

The people who can afford these medications can afford expensive nursing homes. The poor people won't be able to afford the medications, so they'll still end up on Medicaid in the cra*py nursing homes, draining federal funds, imo.

I'm sorry about your loss.
10:10 AM on 10/30/2011
Pelican, Alzheimer's costs trillions of dollars just in providing safe living situations for AD patients. Many eventually can no longer be kept safe at home with a single caregiver because they wander off, even in the middle of the night, or get up at night, turn on the stove and set the house on fire. Two-thirds of Medicaid money goes to keep frail or demented elderly in nursing homes, leaving little left for other needy who can't afford medical insurance.

As long as AD exists with no effective treatments, we'll still be spending trillions of dollars to care for sufferers. That means too little funding for many other needs. I don't know what diseases you're thinking of that specifically affect younger people. There are very few of those. Diseases such as cancer and heart disease are rare in the youngest people, and there are extensive research programs already working on those diseases.

Medicad doesn't relegate one to living in a crappy nursing home. There are many outstanding not-for-profit nursing homes that take Medicaid funding, particularly homes sponsored by a religious group. Yet those religious groups don't proselytize, so residents of any religion are welcome there and not made uncomfortable.
iridium53
Semper Fi
06:46 PM on 10/01/2011
Make sense to me.
Make it happen Cap'n...

Oh, that's right, the nursing homes donate to the Tea-Publicans....

Well, maybe some other time.

Congress has clearly demonstrated that logic and sense don't matter at all when there's a big political donor.
It's all about what money you can donate to the venal, corrupt congress.

Just because it would save money and improve lives - who cares?