U.S. coach Jurgen Klinsmann changed seven starters for the Americans' final World Cup qualifier, starting Brad Guzan in goal in place of Tim Howard on Tuesday night at Panama.
Right back Brad Evans was the only holdover in Panama City on a back line that included central defenders Clarence Goodson and Michael Orozco, and left back Edgar Castillo.
Alejandro Bedoya and Mix Diskerud remained from the midfield that started Friday night's 2-0 win over Jamaica at Kansas City, Kan., which clinched first place in North and Central American and Caribbean qualifying for the third straight cycle. They were joined by Kyle Beckerman, Sacha Kljestan and Graham Zusi in a 4-5-1 formation, and Jozy Altidore remained at forward.
The Americans clinched their seventh straight World Cup berth last month.