John J. Castellani
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John Castellani became President and Chief Executive Officer of the Pharmaceutical Research and Manufacturers of America (PhRMA) in August 2010.

As PhRMA’s President and CEO, Mr. Castellani leads an organization that represents America’s leading pharmaceutical research and biotechnology companies, which directly employ more than 600,000 men and women nationwide working to create new medicines that help patients the world over fight disease and live longer, healthier lives. PhRMA members are among the most innovative research-based companies in the world, investing an estimated $45.8 billion in new medical research and development in 2009 alone.

In assuming his new responsibilities, Mr. Castellani has pledged that PhRMA will continue to lead efforts to find patient-centered solutions to health care challenges in America and around the globe. In particular, PhRMA will focus on helping to successfully implement – and improve – the recently enacted health care reform law and will work to build a dynamic environment in the U.S. that promotes and rewards medical innovation.

Before joining PhRMA, Mr. Castellani was President and Chief Executive Officer of Business Roundtable, an association of chief executive officers of leading U.S. corporations with a combined workforce of nearly 12 million employees and $6 trillion in annual revenues. Business Roundtable was cited by The Financial Times as "the most influential chief executive lobbying group in the U.S." and is at the forefront of public policy debates, advocating for a vigorous, dynamic global economy. Mr. Castellani served at the Business Roundtable from May 2001 to July 2010, where he significantly strengthened the Roundtable’s reputation in Washington, DC, nationally and internationally.

Under Mr. Castellani, the Roundtable played vital roles in the adoption of long-awaited civil justice reform legislation in 2005, approval of the Central America Free Trade Agreement, and enactment of critically important legislation to lower tax rates and slash taxes on dividends in 2003. He also was a leader of the coalition working in support of Social Security reform, the “Divided We Fail” partnership formed to urge Congressional action on health care reform and retirement security, and other initiatives to keep the United States competitive and a global hub of innovation.

Mr. Castellani is frequently sought-out by the news media for his expert insights on business and public policy issues, appearing on such programs as NBC’s “Meet the Press,” PBS’ “The NewsHour with Jim Lehrer,” Fox News Channel’s “Special Report,” and CNBC’s “Street Signs.” He also regularly testified before Congress on issues of key concern to Business Roundtable, and discussed the Roundtable’s agenda for economic growth in venues such as the Detroit Economic Club and the National Conference of State Legislatures.

Prior to becoming President of Business Roundtable, Mr. Castellani was Executive Vice President of Tenneco Inc., and part of the senior management team that led the transformation of the ailing conglomerate into seven strong companies.

Mr. Castellani’s Washington experience includes serving as Vice President for Resources and Technology with the National Association of Manufacturers, and as Vice President of State, Federal and International Government Relations for TRW Inc. He started his career at General Electric as an environmental scientist and strategic planner.

In 2007, Castellani was named one of the 100 most influential people in corporate governance by Directorship Magazine.

A graduate of Union College in Schenectady, New York, Mr. Castellani now serves on its board of trustees. He is also an Ethics Resource Center Executive Fellow and a member of the Advisory Council of the Business Roundtable Institute for Corporate Ethics in addition to being a member of The Economic Club of Washington, DC. He and his wife, Terry, reside in Washington, DC, and have two sons.

Blog Entries by John J. Castellani

Spring Cleaning the Medicine Cabinets, and Other Ways to Combat Rx Abuse

(1) Comments | Posted May 7, 2012 | 6:15 PM

Medicines can revolutionize our health, allowing us to live longer, healthier, more productive lives. But when misused and abused, they have the power to devastate families and communities -- the problem of prescription drug abuse in America is obvious. Nearly 5,500 Americans are misusing prescription medicines in a...

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An Essential Balance: Preserving Our Commitment to Patient Safety

(0) Comments | Posted February 28, 2012 | 11:59 AM

Coming to work at PhRMA a year and a half ago required a bit of a crash course in the incredibly complex and always evolving biopharmaceutical research sector. In that time, I've come to learn that many industry critics seek to generalize (and sometimes mischaracterize) the development of...

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Extending Rare Disease Awareness Beyond Just One Day

(3) Comments | Posted March 8, 2011 | 4:40 PM

This past Monday was Rare Disease Day, a day dedicated to raising awareness of the myriad little-known conditions that cumulatively affect more than 25 million Americans despite having very small individual patient populations.

This is an important effort. But once Rare Disease Day passed, most of us went back to...

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Plea for President's State of the Union: Support Medical Innovation

(2) Comments | Posted January 21, 2011 | 4:57 PM

Next week, President Obama will report to Congress and the American people on the condition of our nation and his policy proposals for the coming year. In an era of deficit reduction, systemic transformation of health care in this country and increasing global competition, it is our sincere hope that...

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It's Not Enough to Be at the Table

(0) Comments | Posted June 22, 2010 | 4:57 PM

Henry Ford once said that coming together is a beginning, keeping together is progress and working together is success. Throughout this period of economic uncertainty, the member CEOs of Business Roundtable have been at the table with the Administration and leaders in Congress to hammer out a solid path back...

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Proxy Access: A Threat to Successful Reform

(1) Comments | Posted May 14, 2010 | 10:57 AM

There's no question we need to reform our financial system -- America's competitiveness depends on it. But, what type of reform is best for our nation?

From our perspective as business leaders, it's critical that policymakers keep their eye on the problem as they move forward on this issue...

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Cause and Effect: Health Care's New Tax

(1) Comments | Posted March 30, 2010 | 4:10 PM

For months, we've watched the endless debate surrounding health care reform. Even with a bill signed and sealed, health care reform is not over. Now is where the real work begins.

At Business Roundtable, we have worked with Congress throughout this process to find a solution to benefit everyone...

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Putting American Jobs, Competitiveness, and Economic Health First

(9) Comments | Posted September 25, 2009 | 3:09 PM

As America continues on the path to a full and robust economic recovery, business leaders are working alongside President Obama and Congress to forge a path forward, create new jobs, and usher in a new era of economic health.

Public policy can serve as an important catalyst for recovery...

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Health Care Reform: What Works for Business Is to Keep Working

(3) Comments | Posted July 31, 2009 | 6:00 PM

With health care dominating the agenda in Congress, the difficulties inherent in negotiating such a massive reform are clear. In the face of this challenge, some have chosen to stand on the sidelines and throw stones at today's health reform efforts -- but now, more than ever, it's critical that...

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