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Silent Spring, BPA and Toxic Health Scares: Let Science Drive Regulation, Not Fear

Posted: 04/ 3/2012 12:00 pm

The term "political science" used to mean public policy studied not just as opinion but based on empirical, documentable evidence. Today it's come to mean something darker--the subversion of science in the hands of ideologues committed to manipulating public policy to their end. This new, and disheartening use of the term can apply to industry groups that put profit ahead of data or advocacy groups of the left or right who believe they are on the side of the angels, empirical facts be damned.

Take the issue of chemicals, a popular flogging horse of reflexively anti-industry organizations. Most writers in the blogosphere, including many with PhD next to their name and working for self-proclaimed public interest groups, have a limited understanding of toxicological science and don't know anything about chemical risk assessment. That's a toxic mix, especially when you're trying to explain the science of toxicity.

The toxic mix of science and politics was on vivid display just last week, when the Food and Drug Administration firmly rejected a "citizens petition" filed by the Natural Resources Defense Council to ban bisphenol A (BPA), which is a plastic additive that lends strength, flexibility and transparency to many plastics and also protects goods stored in containers from spoiling, from all food packaging. The FDA's decision rested on the science, while the campaigns led by the NRDC and a slew of advocacy groups rested on cherry-picking studies that demonized a chemical.

The recent study funded by Silent Spring Institute is an example of this disheartening trend. It's an anti-chemical advocacy group by charter. It recently funded a study that posed an important and provocative question: What can we learn from everyday chemical exposures?

A science-based study would have greatly benefited the public, considering the media reach of this organization. For example, it would be good to ponder why there is such an intense activist focus on, for example, the cancer dangers of chemical exposure when cancer rates continue to fall? Is the focus over chemical risk justifiable? Or as science writer Trevor Butterworth suggests in Forbes, are we exaggerating the hypothetical chemical risk and ignoring the real and growing and measurable and avoidable (but far less media sexy) actual cancer risks, such as obesity, smoking, poor diet, exposure to the sun, drinking and physical inactivity?

Unfortunately, the way Silent Spring framed the research and then reported on it veered from science into the netherworld of political science. The study looked at 213 consumer personal care and cleaning products and identified dozens of chemicals -- everything from cosmetics to cleaners to sunscreens, from phthalates to BPA. The results, published in Environmental Health Perspectives, weren't much, from a science perspective. For example, it presented no evidence and cited no studies to support its claim that the chemicals in question cause any harm to humans at common exposure levels. The few studies that do exist on this subject suggest that health dangers from chemical exposure are declining along with relevant cancer rates.

Instead it broadly linked chemicals, independent of exposure, to such vague, non-clinical terms such as "endocrine disruptor" and "asthma-causing." It documented only the mere presence of chemicals -- then characterized them as the "hidden dangers in everyday products," as one science-starved Forbes contributor compliantly headlined.

The higher end media should have been all over the study. As we learned in junior high science class, substances, including many common foods, such as broccoli or Brussels sprouts, can be "toxic" if we are exposed to high enough levels over a long enough period of time. But as any school kid is also taught, very few regulated chemicals, natural or synthetic, cause harm at typical exposure levels. In this study, there was no pretense of even trying to prove that any of that long list of chemicals actually poses a health risk. The report completely ignored the myriad benefits that chemicals, when used judiciously, bring to people including protecting food safety.

What about the claim that chemicals trigger asthma? As the Centers for Disease Control and Prevention states, asthma is brought on by secondhand tobacco smoke, dust mites, outdoor air pollution such as automobile exhaust, cockroaches, pets and mold. Because almost everything in the modern world includes synthetic chemicals, could they play a role? Anything could, of course, but there is just no evidence that it does at typical rates of exposures, which is what this study allegedly was addressing -- if evidence even matters to campaigners.

What about endocrine disruption? The study makes it sound like exposure to commonly encountered chemicals, such as BPA, pose a health risk at the extremely low levels at which we are exposed to it. But that's not what scientists believe. Over the past two years alone, five prominent international regulatory agencies or toxicology organizations -- USFDA, European Food Safety Authority, World Health Organization, German Society of Toxicology and Japan's Research Institute of Science for Safety and Sustainability -- individually have reviewed thousands of BPA studies by government, university and industry. They've all consistently concluded that BPA is not harmful as used.

Silent Spring cleverly played to the hysteria crowd, framing the issue by writing it analyzed "unlabeled chemicals of concern," even though regulators are not concerned about the low level exposure to these chemicals. The mere invocation of vague terms such as "toxic" or endocrine disruption" without any definitional framing serves only to create emotional havoc among consumers.

Silent Spring got its wish. Headlines such as study finds "dangerous chemicals in household products" or "55 hidden toxics in consumer products" abounded throughout cyberspace. Dedicated anti-chemical groups (and by that I mean those who in their published commentaries selectively present studies to create an ideological narrative rather than addressing the inherent complexity of science, including the usual suspects, such as the NRDC and the Environmental Working Group, and "we don't understand the science chemicals but we know we hate them" journalists at places like Mother Jones carried the water for Silent Spring. The study has generated more than 20,000 stories, with only a literal handful raising the central Chemistry 101 question: does exposure = danger? The answer, for these chemicals at least, is "no, as the FDA demonstrated with its rejection of the BPA petition.

Advocacy groups have learned they can generate articles by breathlessly claiming that a chemical is found in one thing or another at one part per million. That may be hard to comprehend, but it is the equivalent of one human step on a 568-mile walk or one 60-second minute in a two-year span. The CDC provides an important caution against over-interpretation of the detection of an environmental chemical in the body as indicating a health risk. It's clear that Silent Spring, Mother Jones, et al. haven't read it. Or worse, they have read it and don't understand it, or in their zeal to promote politics over science they don't care. When it comes to scientific responsibility and reporting on challenging health issues, it's time for responsible journalists to take the politics out of science.

Jon Entine is senior fellow at the Center for Health & Risk Communication and at the Statistical Assessment Service at George Mason University. Contact him at: jon@jonentine.com.

 
 
 

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11:02 AM on 04/10/2012
"are we exaggerating the hypothetical chemical risk and ignoring the real and growing and measurable and avoidable (but far less media sexy) actual cancer risks, such as obesity, smoking, poor diet, exposure to the sun, drinking and physical inactivity?"

I think we are. But I still believe the hazards of synthetic fragrance are more than hypothetical.

But what about the risks from the components in natural ingredients like essential oils? This study paints all "chemicals' with the same broad brush. Here is an article from an expert in the field of essential oils which examines some of the problems with this study: http://roberttisserand.com/2012/03/ingredient-obsession/
12:39 AM on 04/10/2012
Jon is correct. As a regulatory scientist I know that not one regulator in the world has concerns about trace levels of BPA in human food. Indeed exactly the opposite. Some of the alternatives are far more scary if only for the lack of data to support their safety. The safety data on BPA would fill a very large double garage from floor to ceiling, that on some alternatives would not fill a brief case. If the extensive data available is not sufficient to support the safety of BPA then it is no longer possible to demonstrate the safety of any substance - natural or synthetic. There are very real consequences to excessive and phobic reactions to chemical exposures, not just consequences of cost but also of safety. BPA is very effective at producing safe robust containers and container linings that prevent leaching of metal ions into food and contamination of food by micro-organisms - real risks that can produce real injury.

In the end it is all moot however as manufacturers will respond to market pressure and replace BPA with other materials with consequences that may not become apparent for many years.
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Jon Entine
01:09 PM on 04/05/2012
The problem with your theory, Nicole, is that it is so broad as to be scientifically useless and of no benefit in developing policy solutions. Is it possible that various chemicals in your body have adverse impacts? Certainly, but none of the high profile cases we are talking about, such as BPA, lend itself even to this broad stroke analysis. The most comprehensive independent study on BPA, financed by the federal government--the so-called Teeguarden study http://www.forbes.com/sites/trevorbutterworth/2011/07/25/majestically-scientific-federal-study-on-bpa-has-stunning-findings-so-why-is-the-media-ignoring-it/)--found that BPA does not end up in our "tissues" but is rendered harmless within 24 hours of ingestion through the metabolization process. You post makes a mistake common to those unfamiliar with science--the mere ingestion, or even the presence of a chemical is not an indication of danger or possible harm. Through biomonitoring, we can find minute chemical traces in our urine. As Teeguarden's independent study found, presence in urine does not equate to harm. Banning safe substances, as BPA has been found to be, and replacing them with untested substances merely to satisfy anxiety would be a scientific and public policy nightmare.
03:31 PM on 04/03/2012
Many of the groups that you mentioned have scientists who are trained and specialize in understanding how chemicals impact our health, leading the charge. I'm sorry to say, but your credentials don't qualify your criticisms behind the reports any more than those you falsely accuse. As a matter of fact, a large number of scientists DO believe that small doses of BPA impact our health. Unborn babies and children are especially vulnerable to chemical exposures because their bodies are in the developing stages, and BPA is one of the chemicals present in so many everyday products they come into contact with. Childhood cancers have increased by 40% over the past 30 years, as has our use of BPA in consumer products. And we do know that BPA has estrogenic affects that can be a factor in cancer.

I agree, let science drive regulation not fear. The chemical industry loves to use the fear-inducing cliches of loss of jobs, loss of innovation and loss of competitiveness if we modernize chemical regulation. The fact is that modernized policy will result in innovation, new products and safer/healthier modern-day options.

For a thorough explanation of the FDA's decision on the matter: http://www.time.com/time/health/article/0,8599,2110902,00.html
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Jon Entine
04:36 PM on 04/03/2012
Instead of reading third party "explanations, I highly recommend reading the ACTUAL decision, which makes it clear that the NRDC's petition was outside the body of the most modern, mainstream sciencE: http://www.fda.gov/newsevents/publichealthfocus/ucm064437.htm The studies showing "DANGER" from BPA do not remotely match how humans are exposed to BPA. The USFDA's decison that BPA is safe as humans are currently exposed is in line with EVERY major regulatory body in the world. Not one science body has found BPA harmful. The bans have come from political bodies. NO SCIENCE based regulatory or oversight organization in the WORLD has recommended a ban. Then there's the NRDC.... You can believe independent scientists or not. Your choice.
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Jon Entine
04:58 PM on 04/03/2012
Flat out, BPA is not carcinogenic and no scientist claims it is. Read the CDC report, the NIEHS report, the NTP report or any study, including the WHO study. Has childhood cancer increased by 40% over the past 30 years as you claim? In 1996, the National Cancer Institute reported the frequency for cancer of all types in children increased 10% between 1973 and 1991. During this period, adult brain cancer and soft tissue sarcoma each increased more than 25%, suggesting that children are not facing especially acute challenges. Scientists believe increases in childhood cancers and soft issue sarcoma are almost entirely linked to better tracking methods . In 1999, the NCI reported that this increase in childhood cancer leveled off after 1990 and has not increased significantly since. The Cancer Surveillance Series: Recent Trends in Childhood Cancer Incidence and Mortality in the US, noted, “Our analysis found no large increases or decreases in incidence from 1975 - 1995 for major categories of pediatric cancers in the United States. The slight increase in childhood brain tumors from 1983 through 1986 is consistent with enhancements in diagnostic techniques and changes in classification." COULD any chemical or many chemicals contribute to adverse health? Certainly it's possible. That's why scientists perform empirical tests. That's why the FDA reviews them. IThe FDA followed all major scientific bodies in concluding BPA is not harmful. That may not fit your agenda, but science performed by independent regulatory agencies is not supposed to fit anyone's agenda.
03:20 PM on 04/03/2012
This is a very broad and false generalization of what is taking place in the debate on toxic chemicals, public health and policy.

The fact is that the scientific understanding of how chemicals impact human health has evolved drastically since the legislation meant to create a system for managing and regulating exposure to chemicals, was first created and passed in the 1970's. As a nation that prides itself in innovation, we should easily understand that our scientific knowledge has evolved from the 70's when we thought it was the size of the dose at the time exposure, to now where we understand that our bodies accumulate chemicals in tissue over time as we are exposed. This chemical cocktail, when combined with our genetic pre-disposition, can trigger all kinds of serious illnesses.

In the meantime, our policies around toxic chemicals date back to polyester leisure suits and 8-tracks of disco, and nothing much has changed since. In fact, chemicals get a free ticket into the marketplace where they do not have to prove they're safe first. Shocking really, when you consider that most Americans think all kinds of products need to be proven safe for public health before being available for sale.