More

Featuring fresh takes and real-time analysis from HuffPost's signature lineup of contributors
Michael Sigman

GET UPDATES FROM Michael Sigman

The Genetic Reason Some Of Us Are Happier

Posted: 09/28/11 09:21 AM ET

I once dated a woman who was happy. She slept well, ate when she was hungry and exercised when her body needed it. I had insomnia, ate gallons of chocolate chip ice cream and ran eight miles a day. She felt good when something good happened and bad when something bad happened. I felt anxious no matter what happened. She shared her dreams of verdant meadows and flowing rivers. After a time, I stopped sharing my naked/unprepared for the final exam reruns.

We both had plenty to be thankful for, and she experienced more real-world tragedy than I. I didn't want her to be neurotic, but it seemed unfair that she got to be so much happier.

A new study by UCLA life scientists found that the oxytocin receptor gene (OXTR) is a strong predictor of optimism and self-esteem. Apparently, if you're missing certain nucleotides at a specific location on that gene, you're much more likely to see the glass as half full. If you have 'em, the researchers say, you're likely to have "substantially lower levels of optimism, self-esteem and mastery, and significantly higher levels of depressive symptoms" than your more fortunate brethren.

This survey has been hailed as a breakthrough, but its basic message -- that humans are born with a tendency toward a "happiness quotient" -- comes as no great surprise. Google the phrase "happy gene" and you'll get various older citations pointing to the conclusion that about half of our sense of well-being is inherited. Other scientists claim that a different gene (5-HTTLPR) regulates the neurotransmitter serotonin, aka the "happy hormone."

And then there's the "happy hour gene," which may explain why some of your friends can drink you under the table and still wake up on the right side of the bed the next morning.

Some reacted to the UCLA findings by connecting the news with the desire -- presumably among the happy-gene deprived -- to achieve better living through chemistry. One blogger led with, "Happy Gene Discovered by UCLA Researchers (And It's Not Called Cocaine)." And there was a spirited Facebook thread which confused oxytocin with OxyContin, a powerful narcotic that makes people so happy that if it weren't also highly addictive, we could just put it in the water supply and forget the whole discussion.

I'm convinced, of course, that I possess the glass-half-empty gene -- a certainty that may be evidence I'm right. But the survey results also brought a sense of relief that my default state of mind isn't some kind of weakness.

In fact, scientists behind the UCLA survey emphasize that the effects of the happy gene are far from determinative. If you have the gene for green eyes, you will have green eyes. But the happiness gene appears to be more malleable. Myriad factors -- a mother's nurturing, good sex, close friendships, therapy, exercise and meditation practice -- can improve your oxytocin levels and facilitate optimism and self-esteem.

I mentioned this to a Type-A friend whose basic feeling-state is a cocktail of dread mixed with self-laceration. He was too busy multi-tasking to give a considered reply, but managed to blurt, "No time for sex, meditation or exercise! Perhaps I can do all three at once."

It does no good to fret about our genes. Besides, happiness is in the eye of the beholder. As one of my favorite Genes -- Pitney -- observes in song, "To you it may seem like misery but, for me, this is happy." Self-pity may be counterproductive, but I would have been unhappy growing up in a town without Pitney.

After reading about the UCLA study, I resolved to find out more about how the other half lives. So I visited the Facebook page, Happy Gene. This did not make me happier because I ran head-on into the message, "Happy only shares some information with everyone. If you know Happy, add her as a friend or send her a message."

If you're lucky enough to have the happiness gene, no need to ruminate about the whys and wherefores. You're probably not reading this anyhow. You're having too good a time white-water rafting, marveling at a sunrise or just basking in the wonderfulness of your own company.

 

Follow Michael Sigman on Twitter: www.twitter.com/majorsongs

I once dated a woman who was happy. She slept well, ate when she was hungry and exercised when her body needed it. I had insomnia, ate gallons of chocolate chip ice cream and ran eight miles a day. Sh...
I once dated a woman who was happy. She slept well, ate when she was hungry and exercised when her body needed it. I had insomnia, ate gallons of chocolate chip ice cream and ran eight miles a day. Sh...
 
 
  • Comments
  • 64
  • Pending Comments
  • 0
  • View FAQ
Comments are closed for this entry
View All
Favorites
Bloggers
Recency  | 
Popularity
Page: 1 2 3  Next ›  Last »  (3 total)
04:09 PM on 10/23/2011
It's all a balance isn't it? Genetic predisposition, environmental factors, thought patterns, habits be they good or bad; they all play their part in our happy vs. unhappy natures. If you've never had clinical depression or any other mental illness, don't pretend that you can think it away. You wouldn't do it with cancer patients or diabetics, or at least I hope you wouldn't.

The more science discovers about emotions, the better they can help those of us with mood disorders. I'm glad it's being studied because it gives me hope that I won't have to struggle to stay "happy". Maybe someday I'll be better.
10:20 PM on 09/30/2011
Depression is just another word for disappointment. Not taking a chance can lead to a lifetime of disappointment and regret. Some feel that happiness is getting your own way. I believe it has more to do with of the mind, or less with what is ingrained, or genetic, or chemical. To my way of looking at things, I must surround myself with happier people; not simpler or more or less intelligent. And Not necessarily objects. One has to remember that whether it be money, or posessions; all we can take with us are memories, so they better be good.
photo
HUFFPOST SUPER USER
Litho-stone
Those who believe in telekinetics, raise my hand
03:46 PM on 10/04/2011
"Depression is just another word for disappoint­ment"

You obviously do not know what depression is.
03:56 PM on 10/23/2011
I agree with Litho-stone. You haven't a clue what depression is. It's fortunate for you I suppose.

It's a medical, chemical illness. A cancer patient isn't going to get well if you tell them to "surround themself with healthier people." It's not that simple. Neither is depression. And it's certainly not a synonym for disappointment.
photo
HUFFPOST SUPER USER
TNTtnt
Spend Your Days As You Want To Spend Your Life
06:48 AM on 11/21/2011
double ditto... Clinical depression is a medically-recognized illness. It can be tested for, it can be diagnosed, and it can be treated. Treatment varies from one person to the next, but when the right combination of therapy and/or medication is found, a life-changing difference can be had for that person. It's like coming into the sunshine & warmth, after being in bitter cold.

"Continue as You Intended when You Began" Mark Twain
01:01 PM on 09/30/2011
Interesting article -- like a lot of not naturally bubbly people, you have great humor. Keep on keepin' on.
01:54 PM on 09/29/2011
I am a happy person. I married someone who is not. It makes me happy that I can help him. We have lovely children but only one it seems has my outlook.

Every day is another chance for bliss. I just take them as they come. Sure I have had many horrible things happen to me in my life, but so have many other people. I just pick myself up, dust myself off and carry on.
HUFFPOST SUPER USER
emmasdolly
01:28 PM on 09/29/2011
A big part of being happy is being useful. People need to feel needed. Most unhappy people are stuck in a world of "I, me, mine". They think they need to be happy before they can do something for someone else. It doesn't work that way. Someone once told me that you get back what you give 10X. And it's true. It may not be immediate and you might not get back exactly what you hoped for everytime, but sometimes it's even better than what you hoped for!
03:00 PM on 09/30/2011
Yeah, and ever heard of "no good deed goes unpunished"? It backfires sometimes too.
photo
HUFFPOST SUPER USER
TNTtnt
Spend Your Days As You Want To Spend Your Life
06:41 AM on 11/21/2011
Being useful is one, having a goal or purpose is another. Sometimes just having the goal to have a goal will work.

"Continue as You Intended when You Began" Mark Twain
This user has chosen to opt out of the Badges program
photo
jacmed
71, female - whatever happened to common sense?
11:04 AM on 09/29/2011
So now there's a happiness gene? Well, I guess so -- they've already "identified" a sadness gene (genetic predisposition towards bipolar disorder, i.e., depression). Hah! Ridiculous! Seems to me that science is looking for a genetic predisposition for everything, from obesity to murder; that way, no one will be held responsible for their actions -- after all, their genes made them do it!!
photo
HUFFPOST BLOGGER
Michael Sigman
01:44 PM on 09/29/2011
A genetic"predisposition" doesn't absolve anyone from responsibility for anything.
03:58 PM on 10/23/2011
AGREED!
10:20 AM on 09/29/2011
Again, which came first, the chicken or the egg? In other words, is it the environment that is responsible for the decrease in nucleotides or genetics? I think there would need to be a more thorough examination of the variables or increased variables.
photo
HUFFPOST SUPER USER
TNTtnt
Spend Your Days As You Want To Spend Your Life
06:30 AM on 11/21/2011
The chicken came first, of course.

"Continue as You Intended when You Began" Mark Twain
wstrvlr
Trust nothing you hear & only part of what you see
10:01 AM on 09/29/2011
I decide each day to be happy. I decide each day to deal with what comes to pass. To either accept the things I have no control over or decide how I react to those situations. Life is a series or choices, how we react to what we come to face each day & a decision to love, laugh & enjoy each day we are given.

Embrace each new day with joy, accepting Life's challenges. It doesn't matter if you are rich or poor in material things or where you live. What matters is how YOU react to a situation that makes the difference in what level of stress you will have.

Take time daily to sit & think about the blessings you have & take for granted. Enjoy each sun beam, breeze blowing, birds singing, etc. Savor each kindness someone shows or does for you. Close your eyes & relive each act of caring that says YOU are someone special someone shows you! It can be as simple as someone's smile, a hug from your child or partner or a nice thing someone did for you.

Laugh! People just don't seem to laugh much any more. I laugh every day even if I have to look in the mirror & see that old face looking back at me. That old person has the eyes I had when I was young, but that face I see sure gets me to laughing at the trick Nature got a kick at playing
09:42 AM on 09/29/2011
You are as happy as you make up your mind to be, genes notwithstanding.

It's like walking - you stand up, you take a step, you pick yourself up when you fall, and you just keep walking until it becomes natural to you. Happy is the same. I could "choose" to dwell on my rotten childhood or I can choose to learn the lessons and rejoice that I survived the learning. And to decide NOT to do that to anyone else and spoil their life in large or small ways.

The real trick is to continue to practice happy as you get older, or be ready for a miserable few decades of loneliness, because people do not intentionally want to spend time with unhappy folks.

Practice happy. Be an actor portraying a happy person. Not giddy, not gushy, not funny, but serenely.
Practice lifting the corners of your mouth - those muscles lifted trigger a lot of good-feeling chemicals.
Prop your fists under your cheekbones and rest your head on them if you are out of practice at natural smiling.
Find things to be happy about. Find people to share happy times. "Happy" is contagious.

Here's hoping you find your happy moments!
04:12 PM on 10/23/2011
Fake it till you make it CAN work, but not always. Sometimes you fake it until you're so tired you collapse and end up in hospital.

You're right about the lifting the corners of your mouth and looking for things to be happy about. But fake it till you make it can lead to serious life threatening problems.
rkeeeballs
rock and a hard place
09:32 AM on 09/29/2011
The reason some are happier is easy... they married well $$$$$...and they qualified for medical marijuana.!!....now forget about this article and all that gene crap !!
photo
celestialmotion
Everything has it's beauty,not everyone sees it
08:41 AM on 09/29/2011
My family hates me , they are late sleepers and slow waker uppers and they have a lot of bad days.
I'm up and on with my day hours before they open their eyes and it burns them up that I'm happy most of the time.
I don't have a secret but I believe in watching every sunrise and every sunset and realizing how lucky I am to get that priviledge.
Maybe mindset has something to do with it. I never knew constant worry to do anything but make someone miserable. If your feeling bad , help someone else , you'll feel better and so will they.
Don't worry , be happy.

Wishing everyone on the Internet today good health and much happiness !
Hoping you all have a great day !!
Especially the people who hate what I just wrote ...
I really hope you all have a great day , at least for today !!!
Try it , you just might like it.
09:31 AM on 09/29/2011
I agree with:
I don't have a secret but I believe in watching every sunrise and every sunset and realizing how lucky I am to get that priviledge­.
Maybe mindset has something to do with it. I never knew constant worry to do anything but make someone miserable. If your feeling bad , help someone else , you'll feel better and so will they.

I question:
My family hates me , they are late sleepers and slow waker uppers and they have a lot of bad days.
I'm up and on with my day hours before they open their eyes and it burns them up that I'm happy most of the time.

You are clearly a mixed bag.
12:57 PM on 09/30/2011
I don't think she meant the 'hate' part literally. (?)
rkeeeballs
rock and a hard place
09:33 AM on 09/29/2011
Wow..you took the word's right out of my mouth...wish I would have married you !!...smart chick..rock on babe !
07:31 AM on 09/29/2011
Interesting. Brain science studies will in a short period of time explain so much about us. A recent study, surveying brains of rich, middle class and poor persons, demonstrate/explain an interesting correlation in general functionality. Apparently, financial stressors, like whether one can pay bills, put food on table, robbing peter to pay paul living, is so taxing, stress inducing and requires so much energy and thought, preoccupying the brain with assault like decision making, that the poor simply function less well, leaving their capacity to absorb other challenges, like decision making required for work, more difficult to manage. It is a vicious cycle. Add to it, less discretionary income for a vacation, the preoccupied poor who must struggle to meet basic needs, dont learn as well when given an opportunities to train, because again they are just tapped out. When you add in growing up in a poor environment, under constant assaults, from the outside people who have, simply state "why dont they just get a job or do like me?" but it apparently is not that simple. Information like this will evolve our understanding. I know there are times when i have the luxury of taking on too much and have seen then my own functionality decline and i then work through, but my basic needs are never in true jeapordy.
HUFFPOST SUPER USER
cb55
07:45 PM on 09/29/2011
Sounds like Maslow's hierarchy of needs.
lovelybunchofcoconuts
It's nice, to be nice, to the nice
02:26 AM on 09/29/2011
I have absolutely nothing against happy people, nothing at all (I mostly am one), but the world needs a mix and being neurotic and anxious and even depressed sometimes is also fine, part of growth and the creative process, very important to civilisation and culture. What are the statistics on anti-depressants, isn't about half the country using them to exercise to their constitutional right to be happy? See, now if all those people just experienced their true feelings of misery, I have a feeling we would have a very different political landscape in pretty short order.
lovelybunchofcoconuts
It's nice, to be nice, to the nice
02:07 AM on 09/29/2011
Town without Pitney, good one (I saw SubUrbia recently, that's why I got it).
HUFFPOST SUPER USER
NeuroscientIst
11:34 PM on 09/28/2011
once again, we find out something fascinating about brain chemistry, and its regulation of us. left to the republicans, science would be where it was when barbers practiced surgery, in those halcyon days of blissful ignorance. .
photo
HUFFPOST SUPER USER
Kellybelle22
Happy medical wife, mom
01:34 AM on 09/29/2011
Thank you on behalf of all scientists. I loved your comment and love your profession, too. Am about halfway toward an academic doctorate to go with a medical background in clinical emergency med. If left to the right side, we'd see the end of far too much stem-cell and neuroscience research, among others. It's unfathomable.
photo
IMRITENOTU
Gonnae no dae that
02:27 AM on 09/29/2011
Prejudism is a sign of ignorance mr science.
04:04 PM on 10/23/2011
Uh, prejudism isn't a word. Prejudice is though. Remember to use the right word if you want to throw it around. ;)