Certainly, on a superficial level, we can say that all of the major Mad Men characters journeyed forth through significant life changes. But as much as these characters gained scars and wisdom through their journeys, none of them actually changed over the course of a decade.
This week's episode, "Tea Leaves," deals with the passing of time. The constant fear of death and change are both about the fear of being replaced, of the younger honchos taking over as time moves forward.
Henry, Betty's politician husband, to his credit, never once shames her for her changing looks. I can't say the same for "Mad Men" viewers, many of whom appear to see Betty's weight gain as a reason in and of itself to dislike her.