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Cell Signaling

Life and Death Decisions by Cells, Investigated Under Life-threatening Conditions During WWII

James A. Shapiro | Posted 05.14.2013 | Science
James A. Shapiro

How cells make these signal-influenced choices is a major focus of contemporary, 21st Century research. The truly heroic story of Rita Levi-Montalcini illustrates how dedicated and inspired scientists can address advanced questions in the most difficult of circumstances.

Sociobacteriology: Small Cells Talking And Listening -- And How It May Affect You If You Go Under the Knife

James A. Shapiro | Posted 12.16.2012 | Science
James A. Shapiro

In the early 1980s, I was fortunate to observe that lab strain E. coli colonies are organized structures displaying spatially differentiated expression of their genomes. Each colony was a flower. This observation immediately told me that the bacteria grew as interactive populations capable of coordinating their activities.

Natural Genetic Engineering and Vitalism: What's the Difference?

James A. Shapiro | Posted 07.15.2012 | Science
James A. Shapiro

In a very complimentary blog entitled "Seeing Past Darwin II: James A. Shapiro," James Barham poses the following question and then chides me gently for not answering it: "But if natural selection cannot explain natural genetic engineering, what can?"