Public discourse around the subject is governed by media guidelines that operate to suppress discussion, such as this one from GLAAD: "Journalists should avoid overemphasizing the role of surgeries in the [gender] transition process." For me, you could not overemphasize the importance of sex-change surgery if you tried.
Recently there has been a spate of blog posts raising the specter of transgender people regretting transitioning. They cite their two favorite studies, without actually looking at what the actual studies said, and drag out some old anecdotes. Let's deconstruct the arguments being trotted out one by one.