I can't say, on the basis of evidence, that NIH is misdirecting vast fortunes from where they could do the most good within our lifetimes. But I certainly do believe it. What I can say is that biomedical research dollars are subject to the same myopia that tends to dominate our personal lives.
In this era of global political revolution, fueled by an ongoing communications technology revolution, there is a quiet but equally profound revolution afoot in health care. It's called, simply, personalized medicine.
One of the biggest challenges in finding new medicines is in the battle of infectious diseases, because the disease-causing microbes or organisms are constantly evolving to survive and they mutate quickly.