When I was pregnant with my first child 17 years ago, I had the usual worries compounded by my knowledge as an obstetrician and high-risk pregnancy specialist. I knew first-hand the impact of prematurity and other complications. Like other moms-to-be, I hoped to deliver a healthy baby. As a research physician, I was eager for evidence-based knowledge to make this a reality.
There is a certain comfort that comes from prescribing an approved drug for its FDA-indicated purpose. However, the most exciting news in preterm birth prevention resulted from two studies published in 2003 using compounded progesterone. Since then, the involvement of Pharma and the FDA seems only to have undermined patient care.