Packed lecture halls and being one in a sea of 80 or more students is a common image of a college classroom. However, at a small school like mine, Keene State College, no student is lost in the masses.
It has been my own experience, in five different colleges and universities, that the small school sector may exhibit a bit more enthusiasm for reaching out to sister institutions to leverage relationships through partnership programs and collaborative enterprises.
You've looked around; you've talked to faculty; you've met with staff; the coach has shown you the locker room and the resident assistant has shown you the room. You love it here or you hate it here, and that's going to be the most important factor.