In some cultures, over the millennia, inter-sexed people have even been revered as shamans and holy people - they are closer to the ideal of a balanced, universal soul. Think of the Yin/Yang symbol. We all know it. It means 'balance' - male/female balance.
While the loss of Angie Zapata is tragic, the fact that with due process a trial was held and a conviction obtained speaks to how greatly America is altering its nature with regard to acceptance of transgender individuals.