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Peter Hotez, M.D, Ph.D.

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The London Declaration: A Tipping Point For The World's Poor

Posted: 01/30/2012 7:20 am

A moment like this doesn't come around often. In London today, global health leaders -- the CEOs of major pharmaceutical companies, Bill Gates, WHO Director General Margaret Chan, senior government officials from endemic and donor countries, and others -- announced an unprecedented commitment to control or eliminate 10 diseases by the end of this decade.

The neglected tropical diseases, or NTDs, are the most common afflictions of the world's poorest billion people. They are ancient scourges such as hookworm, elephantiasis, river blindness, schistosomiasis, trachoma and guinea worm.

The NTDs are probably the most important diseases you have never heard of, but a massive body of evidence accumulated over the last two decades has revealed they are a major, yet stealth, reason why the poorest people living in Africa, Asia and the Americas -- the so-called "Bottom Billion" -- cannot escape poverty.

Chronic hookworm infection affects an estimated 600 million people and may be the world's most insidious poverty trap. It stunts physical growth and dramatically reduces intelligence and memory in children, reducing future wages by almost 50 percent.

Elephantiasis and river blindness infect approximately 100 million people, taking a particularly heavy toll on subsistence farmers and laborers who can least afford to lose daily wages to chronic sickness. As a result, countries like India and Ghana lose hundreds of millions of dollars in lost agricultural productivity every year.

But it is the girls and women with NTDs who suffer the most.

Urinary tract schistosomiasis is a disease that impacts more than 400 million people in Africa. Every day, young girls suffer from spiny parasite eggs deposited in their bladder that cause bleeding when they urinate. Until recently, medical examinations failed to make the connection between the lesions that more than 100 million African girls and women have in their upper and lower genital tracts -- a source of terrible pain, bleeding, shame, stigma and depression -- with another devastating disease: HIV/AIDS. Now we know these girls and women have a three- to four-fold increase in risk in acquiring HIV/AIDS. It's the single most important co-factor in Africa's AIDS epidemic and virtually nothing has been done about it.

Until now.

Today we are breaking a vicious cycle of NTDs and poverty affecting the world's poorest children, subsistence farmers, and girls and women, by accelerating efforts to control or eliminate many of these chronic and stigmatizing infections.

NTD treatment has become one of the most cost effective global health programs, costing only 50 cents annually, on average, to treat multiple diseases at once, in large part because major pharmaceutical companies are donating the needed medicines for free.

Imagine wiping out what may be the single most important poverty trap, and doing it for less than the cost of a candy bar!

The London Declaration on Neglected Tropical Diseases serves as a new generation Marshall Plan for the bottom billion, but with a priority on girls and women living in poverty to wipe out the 10 most common NTDs by 2020.

It brings together a unique group of partners that will work together to eliminate the most common NTDs by 2020. We have a wealth of lessons to draw from, including the success to date in eliminating elephantiasis, river blindness and trachoma in more than 30 countries, as well as nearly eradicating guinea worm from the planet. The increase in drug donations and government and philanthropic support -- combined with broader general public awareness -- allows us to expand on these achievements to combat hookworm, female genital schistosomiasis and other high prevalence NTDs. It will accelerate research and development for new drugs, diagnostics and vaccines for NTDs and lead to faster collaboration between non-profit product development partners, major pharmaceutical companies and governments.

We have a unique opportunity to meet the World Health Organization's 2020 targets for NTD control and elimination. Success would represent one of the most cost-effective means to lift 1 billion people out of poverty and prevent needless suffering among future generations.

There is much work to be done, but together, we can see the end.

To view a webcast of the London Declaration, visit the Global Network for Neglected Tropical Diseases web site, www.globalnetwork.org.

Peter Hotez, M.D. Ph.D., is President of the Sabin Vaccine Institute, Director of the Sabin Vaccine Institute and Texas Children's Hospital Center for Vaccine Development, and Dean of the National School of Tropical Medicine at Baylor College of Medicine.

For more by Peter Hotez, M.D, Ph.D., click here.

For more on NTDs, click here.

 
A moment like this doesn't come around often. In London today, global health leaders -- the CEOs of major pharmaceutical companies, Bill Gates, WHO Director General Margaret Chan, senior government o...
A moment like this doesn't come around often. In London today, global health leaders -- the CEOs of major pharmaceutical companies, Bill Gates, WHO Director General Margaret Chan, senior government o...
 
 
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03:06 PM on 02/10/2012
Every problem is made harder to solve with the worlds ever growing population. The world added a billion people in the last 12 years and that continues to grow. We have a food crisis, a water crisis, a disease crisis, an HIV crisis, an oil crisis, a climate change crisis, a financial crisis, a jobs crisis and an over population crisis. The ever growing world population is not sustainable and make the problems of hunger, poverty and despair harder to solve.
06:54 AM on 02/02/2012
I say they need to really get down to the real Problem in the whole world That not only causes multible diseases,kills,injures others and that is ALCOHOL............Period End of Sentence..They keep escaping what the real killer is world wide and always,always blame PASSIVE SMOKE...Which is a LIE
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Paul Houston
British and a London resident
04:29 PM on 01/31/2012
The moment somebody comes up with a plan to eradicate diseases which kill, maim and impoverish by making vaccines available to the poorest members in the world, the nay sayers come out saying it is a plan for big pharma to make money! Well if vaccines make so much money for the pharma industry, why are so few of the pharmaceutical companies making them? All the money is made in selling drugs for "lifestyle" diseases of rich westerners.
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Lorenzo&BushH8ter
03:34 AM on 02/03/2012
On a global scale, the wealthy are having to look to third world countries for labor supply in the future.
America and other countries, as a whole, is not of any worth to the world. Aging and not worth their time or money.
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maribelles
have opinion? win fans, lose fans
07:24 AM on 01/31/2012
Another plug for big pharma, who continue to want to make you believe that THEY hold the key to health, dragging out the inevitable yarns about exotic diseases from 4th world districts in 3rd world countries (diseases present mostly due to unresolved power structures) - while western cultures which should have the strength and fortitude to help others less fortunate continue to deteriorate due to being over drugged and partaking on a consistently degraded food system they are less and less in control of. And this is supposed to be good news? Yes- there is much work to be done, but it needs to be "done" a different way, by empowering people and cultures in their connection with their lands and nature, not through increased control by the CEO's of Big Pharma and Bill Gates.
12:34 PM on 01/31/2012
No matter what the reason it is still a good idea. As Rabbi Stanley Dryfus said numerous times, "A mitzvah done for the wrong reason is still a mitzvah."
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Madame Tiffany
09:38 PM on 01/31/2012
Well said!
01:36 PM on 01/30/2012
This is excellent. Here's to hoping to relieve the world's poorest from the ravages of preventable diseases. I'm not sure why they need to politicize it and place an emphasis on females over males. Perhaps they are not but that is how the article reads. It leads one to believe that women are more important than men when both are just as important and deserving of care as the other.
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Bradley Scott Roon
not left or right: think for yourself
12:39 PM on 01/30/2012
First of all, if you look at the actual science, AIDS is not HIV. Even though dated, the Duesberg book will give you enough background to indicate the virologists are wrong again. (They lost the war on cancer and so they needed another target to get funding for survival)
Second, yes it would be absolutely fantastic to get these diseases eliminated. With the life cycle of the illnesses it is unlikely to be a possibility. Treatment in the humans? probably doable. What scares me is the drug pusher connection.
All drugs are toxic. All have bad side effects. Does that preclude their usage for critical care or dangerous symptom suppression? Of course not, it is simply that drugs are NEVER going to establish actual health and will negatively impact one's health if used chronically. Even an aspirin damages the kidneys after 2 weeks. Acetimonephen destroys some antioxidants in the brain increasing Alzheimers, and the list goes on.
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Bradley Scott Roon
not left or right: think for yourself
12:38 PM on 01/30/2012
Another scary part of this proposal is that all drug pushers are looking for profit. They don't really want to remove the illness which garners them a profit. It doesn't pay, and before you get your hopes up about Gates, remember than he bought $500 million into Monsanto last year. Monsanto's products are literally forced upon you, are unsafe as GMOs in your body (85% of all non-organicv food has GMO crap) and their herbicide is persistent, systemic, neurotoxic at HALF the allowed residue level set by the FDA when monsanto employee Michael Taylor was in charge (the first time) it is an endocrine disruptor, a mutagen, and anything grown with roundup/glyphosate is GUARANTEED to have poor nutrition. Glyphosate kills so many things because it prevents the uptake of ionized minerals in a broad spectrum. That means you can't get them from plants that don't have them. 200 autopsies of death by heart attack: every single one had a selenium deficiency. 200 autopsies of stroke victims: everyone had a copper deficiency. You NEED these minerals you will no longer get. That's what Gates is supporting - a corporation whose intent is to literally control the food chain. In their 1999 meeting w/Anderson and Assoc, monsanto stated their goal as "if it's something that's grown, it's something that we own." That means patented. That means toxic GMO.
These people planning this are not altruists.
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maribelles
have opinion? win fans, lose fans
07:25 AM on 01/31/2012
Absolutely.
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Madame Tiffany
09:41 PM on 01/31/2012
The plot thickens doesn't it? You have educated me on some information about Monsanto that I was unaware of.....interesting!
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Lorenzo&BushH8ter
03:28 AM on 02/03/2012
And of course, thousands of Indian farmers drink the Monsanto herbicides that were suppose to increase their crop yield, but does nothing but impoverish them. They die an excruciating death from that act. Their government officials buy into the Monsanto program and destroy their own country's farmers.
09:02 AM on 01/30/2012
The big question for our generation is how to reform capitalism so that it provides benefits for those who are externalized from the wealth equation. Charity and multilateral aid are two possibilities, but are they enough?

John J.P. Howley
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C Karen Stopford
07:29 AM on 02/05/2012
The only way to cure gangrene is amputation.
07:26 AM on 01/30/2012
Very good news. So little heard previously from the wealthy in Africa, from the wealthy rulers of African countries. They have no role here?
04:21 PM on 01/31/2012
About two decades ago a leader of an African country, Niger, complained the financial need for just HIV/Aids in his country was more than the gross national product. How would he be able to get wealthy in that situation?