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Sierra Alef-Defoe

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Cancer Research Should Be a National Priority

Posted: 05/18/2012 9:40 am

If a terrorist targeted almost two million Americans per year and killed over half a million of them, the U.S. would almost certainly declare war. Why, then, have we not put the same effort into fighting cancer that we have into fighting wars?

Cancer kills more people every day than terrorists killed on September 11, 2001. Yet our country fails to prioritize cancer as a national issue.

Unfortunately, cancer has touched the lives of most Americans. When I posted on Facebook that I was interviewing for this blog post, I received a flood of messages that put my former interview requests to shame. Even among my predominantly young network of Facebook friends, everyone knows someone who has had cancer. That's not surprising considering that in the UK, for instance, four in 10 people are diagnosed with cancer in their lifetimes.

The issue that has a place in everyone's heart needs a place in our nation's priorities.

We cannot settle for chemotherapy, radiation and surgery. These are not cures: They do not work for everyone, they do not work for every type of cancer and they only work so many times. These treatments often do more harm than good due to their destructive natures.

"There's a lot of research to treat cancer the first time around and the second time around," said Ashley Gaston, whose father has suffered from cancer twice. She fears that the treatments that helped him survive would not be able to save him if the cancer came back again. "Cancer doesn't give up that easily."

Cancer is a persistent and strong enemy, which is why it is so important for our nation to fight back with full force.

National attention has proved to be an effective catalyst in bringing about major change. Breast cancer has become a highly publicized issue, thanks in part to the Susan G. Komen Foundation, which has made its pink ribbon a common household symbol. This mobilization has contributed to advancements in breast cancer research that have made it a highly treatable disease with promising survival rates. A national call to action against cancer works -- we just need to make it against all cancers.

"A few types of cancer receive almost all the funding," said Kelsey Josund, co-founder of the Pink Polka Dots Guild, which raises money for pediatric brain tumor research. "But all people affected by cancer deserve a cure."

Systemic improvements can help to advance the fight against all types of cancers. More funding for unconventional proposals could mean the difference in the quest for a cure.

"We need to be bold and go for high risk, high reward ideas," said Dr. Jim Olson, a researcher at the Fred Hutchinson Cancer Research Center in Seattle. And he would know: His lab took a leap of faith in researching the venom of the Israeli deathstalker scorpion. They found that they could use the venom to light up cancerous cells, so that cancer surgeries will be more successful with fewer side effects. Innovations like this are what we need in the fight to end cancer. "Tumor Paint" is now moving to clinical trials and will ultimately see the Food & Drug Administration's approval. But before the review process can even begin, the project needs initial funding, which typically comes from the National Institutes of Health (NIH).

The NIH, which funds most cancer research, has plenty of room for improvement. Its review process leaves some wondering if the treatment that could save their lives is stuck without funding. Expediting the NIH's review process could get life-saving treatments to the public faster.

"The best change [to the NIH] would be setting up a mechanism by which reviewers could anonymously send an email to researchers if they have a question while reading the grant," said Olson. "If a question arises, there is no way to get it answered, and in many cases, the grant doesn't get funded. Then it takes most of a year before it can be re-submitted, in many cases just to answer questions that could have been answered in 15 minutes."

Beyond efficiency, there is of course the most sweeping solution of all: a simple increase in research funding. Surely there are areas of spending on the federal, state and individual levels that are less vital than cancer research.

"For every 11 grants that are written by researchers, only one gets funded," said Olson. "Because of this, many researchers spend much of their time writing grants instead of doing research."

The more ideas we can fund, the more likely that one of them will lead to a better treatment, or even a cure.

"Sure, some of it will not work, but we should not be so afraid of failure," said Olson. "...We are not on the cutting edge if every experiment succeeds."

And the U.S. certainly needs to be on the cutting edge of cancer research. We should be prioritizing cancer research as we did space travel in the mid-20th century. A strong national campaign such as the space race would inspire the innovation that is necessary to find a cure. After all, if we can send a man to the moon, we should certainly be able to fight malignant cells.

"With our vast supply of universities and pharmaceuticals, this is the ultimate opportunity to focus, cooperate, and make this impact," said Josund. "If we are going to lead into this next century, it will be with things like innovative healthcare and taking care of humanity."

Our nation needs to take a united stand against our common enemy. We must not let cancer remain the second-leading cause of death when we have the opportunity to fight it. The U.S. needs to mobilize against cancer so that we can achieve the ultimate victory: a cure.

 
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10:02 AM on 05/19/2012
My father died with Lung Cancer over 30 years ago. My young daughter at age 29 was diagnosed with Breast Cancer when she was pregnant with my first grandson (eight years ago). She is well and I have a healthy grandson. I was recently diagnosed in February with Breast Cancer and am going through radiation. I think it is time we found a cure that didn't mean destroying the body in other ways. Chemo takes your hair, radiation burns the cells; healthy and unhealthy, and drugs that you take afterward weaken your bones. Please let's find a cure that is a real cure! With all the modern advancements we haven't made enough progress in this field to fight this dreaded war against Cancer. It is time to concentrate all our energies toward this.
08:43 PM on 05/21/2012
So true! I was diagnosed with stage 2 breast cancer 4 years ago when I was 40. I was in really good shape and felt great when I was diagnosed. After all the chemo and several years of pills (Tamoxifen, then Arimidex, then Femara), and the removal of my ovaries to get rid of the estrogen fuel source of the cancer, I am a mess. There is not a day that goes by that I don't have a good deal of pain and trouble walking due to all the bone and joint damage caused by all those drugs, and the early loss of all that estrogen. I'm grateful to be alive, but treatment was brutal and the aftermath is a painful daily reminder.

Good luck to you and your daughter.
09:25 AM on 05/19/2012
We know how to drastically reduce the premature deaths and unnecessary suffering that result from chronic and infectious diseases. Unfortunately, there are too many people who profit from the status quo, and too many 'victims' who don't want to alter their lifestyles, for these reductions to occur. So, declare all the 'wars' you want, spend all the billions you want, but until the 'healthcare' providers and the 'patients' are motivated to take the necessary steps to eliminate cancer, it won't happen.
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08:19 AM on 05/19/2012
A lot of things should be a "national priority." A lot of things have touched many lives. And a lot of things will get you a few licks on any Facebook account.
Googling a few facts and making a blog post isn't going to solve anything or even "raise awareness," a stupid phrase if ever there was one.
Please.
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fumes
Midnight Toker
02:50 AM on 05/19/2012
'Fertilizing' bone marrow helps answer why some cancers spread to bones
May 15th, 2012 in Cancer
Researchers found that administering a common chemotherapy drug before bone tumors took root actually fertilized the bone marrow, enabling cancer cells, once introduced, to seed and grow more easily.
While effective at attacking tumor cells, a side effect of cyclophosphamide (and many other chemotherapy drugs) is that it suppresses certain bone marrow cells that help the immune system and increases some harmful cells. Researchers hypothesized correctly that the drug would make the bone marrow more tumor-friendly.
http://medicalxpress.com/print256233774.html
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Antitumor Effects
One study in mice and rats suggested that cannabinoids may have a protective effect against the development of certain types of tumors. [3] During this 2-year study, groups of mice and rats were given various doses of THC by gavage. A dose-related decrease in the incidence of hepatic adenoma tumors and hepatocellular carcinoma was observed in the mice. Decreased incidences of benign tumors (polyps and adenomas) in other organs (mammary gland, uterus, pituitary, testis, and pancreas) were also noted in the rats. In another study, delta-9-THC, delta-8-THC, and cannabinol were found to inhibit the growth of Lewis lung adenocarcinoma cells in vitro and in vivo .[4] In addition, other tumors have been shown to be sensitive to cannabinoid-induced growth inhibition.[5-8]
http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4
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groland
socially left, fiscally right
12:26 AM on 05/19/2012
Right now, I am at an NIH conference. It took me 45 minutes just to get through security and onto the campus. When I worked here in Bethesda in 1990s, there were no gates checkpoints, scanners, or background checks for visitors and nothing ever happened. Now they must employ hundreds of people and spend millions on security. Our over reaction to 9/11 has handed the terrorist a victory.

BTW, as someone working in biomedical research for 30+ years, I can attest that we do not attract the smartest people anymore, despite huge strides in genetics and genomics. The issue is not money as much as it is a lack of original ideas.
George Picard
Send lawyers, guns and money
11:50 PM on 05/18/2012
One day we will cure cancer, AIDS, heart disease, and any thing you can think of. And we will lie dying in a bed dying from nothing.
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Gib
My micro-bio is empty
11:42 PM on 05/18/2012
There is a great deal of cancer research, all over the world. Cancer researchers I've spoken to think that cancer will always be with us.
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Sean Jennings
Gun loving hippie fireman
11:29 PM on 05/18/2012
I would be for the money spent on war going to cancer research but do you know how much money is spent on cancer research each year? Billions of dollars and what has it gotten us over the years. No cures, only treatments. Not one cancer has ever been completely cured like say... Cow pox being taken care of. Sooner or later we need to look more into what is CAUSING the cancer, not dumping zillions of dollars into fixing what is broken. Just my opinion. Oh and cannabis is proving to not only treat people with cancer but itself is showing anti-tumor effects. -Nat. Cancer Institute.
10:36 PM on 05/18/2012
The cure for cancer will come when the research finds out what caused it to be in our midst. The reason there is no money for research is because pharmaceutical companies only or mostly fund efforts that will create expensive treatments and drugs that will in turn bring in more money for a long time. Why would they want to cure cancer? That would be like killing the goose that laid the golden egg. Yes, I am very negative. But think about it and you'll see how much truth there is in what I suspect to be true.
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Mirriam Egglebrecht
07:54 PM on 05/18/2012
Top killers of Americans in the real world: heart attacks, cancer, prescription drugs.

Top killers of Americans according to the US Government: islamic terrorists.
06:58 PM on 05/18/2012
It takes a back-seat behind welfare benefits.
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Tomaniac
Science keeps us from lying to ourselves
09:51 PM on 05/18/2012
And the Military Industrial Complex that makes a fortune on weapons of death.
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Mirriam Egglebrecht
04:04 PM on 05/18/2012
It's true. The US government is sooooo obsessed with terrorists and justifies spending hundreds of billions to hunt them down and kill them and to protect every aspect of our lives from terrorists. But how many American's have ever worried about being killed by a terrorist.

You're much more likely to die from a disease that was caused by toxins in the environment. Toxins that cause cancer for example. Not only should we reallocate funds from hunting imaginary terrorists to finding a cure for cancer we should be educating ourselves on the causes of cancer.

What is in your food? What's in your food packaging? What's in your water? What is in your cosmetics? What is in your vaccines? Are you aware of BPA, parabens, heavy metals? Are you obtaining enough vital mineral content in your food? Are you exercising?

The Environmental Working Group is a good service that rates products by their toxicity.

http://www.ewg.org/

We can march for Komen until the cows come home but what we really need to do is get educated and get the toxins out of our environment.
01:29 PM on 05/18/2012
A pretty outrageous oversimplification. Also, Nixon did "declare war" on cancer...in 1971. http://en.wikipedia.org/wiki/War_on_Cancer
11:49 AM on 05/18/2012
Now only if our politicians made this much sense...I vote for Sierra Alef Defoe to head the task force to cure cancer.
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Mirriam Egglebrecht
04:06 PM on 05/18/2012
Don't expect any solution to come from the government. They are busy hunting the Al Qaeda's that they're also using to overthrow government's in the Middle East. The government doesn't care about the American people.
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08:22 AM on 05/19/2012
Yeah, because task forces are chosen by votes and they cure so many things.
Please.