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Clinical Trials

Adrift in the Waters of Childhood Cancer -- Arguing to Change the Standard of Care

Jonathan Agin | Posted 05.16.2013 | Impact
Jonathan Agin

April 11, 2008 will always remain etched in my memory for one simple reason. It is the day that we heard the words "your daughter has cancer." They are four of the worst words that a parent could ever imagine hearing.

Family Caregivers Are Central to the Clinical Trial Experience

Tory Zellick | Posted 04.09.2013 | Fifty
Tory Zellick

The caregiver is critical to the success of a patient's participation in a clinical trial, because the caregiver is the closest and most constant observer of the patient.

Medicine's 'Hard Drive' Is Crashing

Ida Sim, M.D., Ph.D. | Posted 04.07.2013 | TED Weekends
Ida Sim, M.D., Ph.D.

When 75 percent of our medical costs are for chronic diseases that are largely due to poor lifestyle habits, where are the studies on prevention? On behavior? On effective patient-doctor or public health strategies?

Are We Finally On The Road To Preventing Alzheimer's?

Jessica Langbaum, Ph.D. | Posted 04.02.2013 | Fifty
Jessica Langbaum, Ph.D.

This grassroots movement is only getting started. With your help, we can increase momentum in the fight to end Alzheimer's.

New Treatments, Your Health and Statistics

Marie Davidian | Posted 05.15.2013 | Science
Marie Davidian

Statisticians and statistics are even more fundamental in this era of personalized medicine, as sponsors seek to target treatment to patients most likely to benefit and develop "adaptive" study designs to identify these patients sooner.

Pediatric Clinical Trials Model Optimization of the Caregiver Role

Tory Zellick | Posted 05.14.2013 | Fifty
Tory Zellick

By necessity, pediatric specialists regularly interface with caregivers, because in the case of child patients, the caregivers are the parents or guardians.

Premature Reports of Nails in CAM's Coffin: Of Miracles and Money

David Katz, M.D. | Posted 03.20.2013 | Healthy Living
David Katz, M.D.

Many unpatentable modalities in the realm of complementary and alternative medicine do not inspire huge and costly trials. We need such trials to know for sure what does and doesn't work. In the absence of them, we need to avoid a rush to judgment.

Reading the Fine Print on Cancer Treatment and Side Effects

Dr. Elaine Schattner | Posted 03.19.2013 | Healthy Living
Dr. Elaine Schattner

Researchers found that nearly one-third of reports on large, randomized studies over-emphasize some benefits of therapy. In the majority of reports evaluated, the investigators found insufficient attention or discussion of treatment side effects.

Top 10 Questions to Ask When Considering a Clinical Trial

Tory Zellick | Posted 03.06.2013 | Fifty
Tory Zellick

As you consult with your loved one and weigh the pros and cons of participating in the trial, do include your own needs as a factor to consider -- specifically, the feasibility of the extra caregiving duties required. Keep in mind, however, the decision is ultimately your loved one's to make.

Top 10 Facts You Need to Know about Clinical Trials

Tory Zellick | Posted 03.04.2013 | Fifty
Tory Zellick

Learning about the world of clinical trials is akin to learning to speak a new language, and it can be overwhelming to both caregiver and care recipient -- especially in the middle of a health crisis. So here is a simple breakdown of the top 10 facts you need to know about clinical trials.

There Has to Be a Better Way

Jonathan Agin | Posted 01.28.2013 | Impact
Jonathan Agin

I am convinced that one of the biggest impediments to finding cures for childhood cancer is the way we force our kids to fight. The regulatory and institutional red tape cause many parents not to enroll their children in clinical trials.

The Mammography Muddle

David Katz, M.D. | Posted 01.27.2013 | Healthy Living
David Katz, M.D.

Mammography specifically, and cancer screening in general, is often something of a muddle. We should acknowledge the trade-offs, work toward better screening methods, and in the interim -- muddle through.

Clinical Trials: With Informed Samaritans, a Key Way to Advance Science and Medicine, Benefit Others -- and Receive Leading-Edge Therapies

Glenn D. Braunstein, M.D. | Posted 12.22.2012 | Los Angeles
Glenn D. Braunstein, M.D.

Thousands of clinical trials take place every day in this country and around the world as part of modern science's best attempt to find answers to medicine's most pressing questions.

Television's Assault on Medical Research

Doug Peddicord | Posted 11.25.2012 | Media
Doug Peddicord

Patients who participate in clinical trials should be applauded for their willingness to contribute to medical science. They don't need to be exploited, made fun of or otherwise degraded.

Join the Dream Team and Stand Up to Cancer

Howard Young | Posted 11.07.2012 | Impact
Howard Young

I am a pancreatic cancer survivor. The reason I'm alive today is because some incredibly gifted researchers dared to think out of the box, with the support of Stand Up To Cancer.

Knowing What's Right Could Help Improve Patient-Centered Outcomes

Doug Peddicord | Posted 04.24.2012 | Politics
Doug Peddicord

"Doing what's right isn't the problem. It's knowing what's right." These words, spoken by Lyndon Johnson, could apply to the Patient-Centered Outcomes Research Institute which is clearly trying to "do right" but has shown little evidence that it knows what is.

The Democratization of Health Care: Clinical Research and Quality Health Care for Minority Populations

Gary Puckrein | Posted 04.08.2012 | Politics
Gary Puckrein

The American clinical research system is not designed to maximize the potential for the best possible outcomes of health services that are delivered to all American health care consumers.

Cancer One, War Less Than One

Jonathan Agin | Posted 03.21.2012 | Impact
Jonathan Agin

The FDA and the institutional review boards, rather than being impediments to patients gaining access to potentially life-saving drugs, must become a partner with patients. Regulatory impediments before parents must be eased.

Are Clinical Trials Exploiting India's Poor?

Posted 09.11.2011 | World

Clinical trials have always been part of the pharmaceutical industry, but what if a large number of those trying out new medicines live below the pove...

Dangerous? Keeping An Eye On Trendy Cosmetic Surgeries

Robert Tornambe, M.D. | Posted 09.06.2011 | Healthy Living
Robert Tornambe, M.D.

So my mantra when it comes to cosmetic products and procedures is: show me the science! And I am not talking about fake testimonials or anecdotal experiences.

California Versus the Valley of Death

Don C. Reed | Posted 08.03.2011 | Politics
Don C. Reed

There is a place you will not find on any map. It has no physical location. But it is real nonetheless, and a danger to all mankind. It is the Valley of Death, where new medicines die.

Why Do Clinical Trials Exclude Depressed People?

Posted 05.25.2011 | Home

When the U.S. Food and Drug Administration announced in 2009 that Pfizer Inc's smoking-cessation drug Chantix would need to carry a restrictive "b...

The Problem With Randomized Clinical Trials For Medical Research

Joseph Nowinski, Ph.D. | Posted 11.17.2011 | Healthy Living
Joseph Nowinski, Ph.D.

In this story, Thomas received the new drug, while his cousin Brandon, as luck would have it, was assigned to the control group, given a notoriously ineffective treatment.

Human Embryonic Stem Cells Approved by FDA for Clinical Trials, Yet Totally Ignored by the Media

Paul Abrams | Posted 11.17.2011 | Healthy Living
Paul Abrams

If these new stem cells are safe, and perform as hoped, the first injection in patients that took place last Friday will be the 21st century's "shot-heard-round-the-world".

Would you drink your own urine if it would save your life?

Lisa Guest | Posted 11.17.2011 | Healthy Living
Lisa Guest

A healer from Guatemala suggested I drink my own urine. Is that what my life will become? Instead of my morning ritual with PERO (coffee alternative) I'll be sipping my own morning's waste material?