What does it mean to treat other persons as ends-in-themselves and never merely as means? Well, the central idea is that every human being deserves to be treated with dignity and respect, that in all of our interactions, even with those with whom we disagree, or whom we don't like, or who may even disgust us in some way, we must engage them in ways that recognize their humanity.
What is Judaism's bottom line? In a world in which everything changes, in which marketing often dictates the spin we give to whatever it is we are about to do, what in Judaism isn't negotiable? What in Judaism remains so crucial that if you got rid of that heart, there would be no Judaism left alive?