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Encode

Has 'Junk DNA' Mystery Finally Been Solved?

Posted 05.13.2013 | Science

By: Tia Ghose, LiveScience Staff Writer Published: 05/12/2013 02:25 PM EDT on LiveScience One person's trash may be another person's treasure, but...

Why the 'Gene' Concept Holds Back Evolutionary Thinking

James A. Shapiro | Posted 01.30.2013 | Science
James A. Shapiro

DNA and molecular genetics have brought us to a fundamentally new conceptual understanding of genomes, how they are organized and how they function.

Mobile DNA Repeats and Transcriptional Formatting of the Mammalian Genome in Evolution

James A. Shapiro | Posted 11.22.2012 | Science
James A. Shapiro

There has accumulated considerable evidence outside the ENCODE project that mobile DNA repeats are important both in the organization and in the rapid evolution of complex genomes.

The Value of ENCODE

Nessa Carey | Posted 11.24.2012 | Science
Nessa Carey

Creating a drug to target just one regulator may have little impact. But the more we understand the regulatory networks involved in health and disease, the more chance we have of identifying the key vulnerable pinch points in our organ systems.

Junk DNA, Junky PR

Athena Andreadis, Ph.D. | Posted 09.21.2012 | Science
Athena Andreadis, Ph.D.

The ENCODE Project results don't alter the current view of the genome; they just provide a basis for further investigation. Additionally, the findings were embargoed for years to enable the PR blitz -- at minimum unseemly when public funds are involved.

A Genome-Sized Media Failure

Michael White | Posted 11.13.2012 | Science
Michael White

The genome sciences consortium ENCODE was a fantastic opportunity for scientists and science journalists to explain exciting research findings in genome biology that are changing how we think about health, disease and evolution. But we blew it, in a big way.

Bob Dylan, ENCODE and Evolutionary Theory: The Times They Are A-Changin'

James A. Shapiro | Posted 11.12.2012 | Science
James A. Shapiro

The old idea of the genome as a string of genes interspersed with unimportant noncoding DNA is no longer tenable.

New Genome Guidebook Solves Mystery Of 'Junk' DNA

Reuters | Posted 11.05.2012 | Science

* 'Junk' DNA runs the genes, $196 million international study finds * Project offers 'guidebook to the human genome' * ...