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Fission Yeast

Legitimate and Illegitimate Recombination: Targeting Homologous Exchange for Multiple Adaptive Purposes

James A. Shapiro | Posted 10.02.2012 | Science
Read More: Mouse Genome, Sleeping Sickness, Budding Yeast, Non-Homologous Recombination, Lyme Disease, Homologous Recombination, Recombination, Fission Yeast, Site-Specific Recombination, Rochelle Esposito, Trypanosoma Brucei, Borrelia, Science News
James A. Shapiro

The molecular studies are remarkable in uncovering a striking variety of ways cells have adapted homologous recombination for diverse purposes.

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Can Cells Bias Natural Genetic Engineering Toward Useful Evolutionary Outcomes?

James A. Shapiro | Posted 08.06.2012 | Science
Read More: Retrotransposons, Target Specificity, Transposons, Bias Towards Useful Changes, Slime Mold, Site-Specific Recombinase, Integrase, Fission Yeast, Dictyostelium Discoideum, Budding Yeast, Natural Genetic Engineering, Transcription Factors, Transmissable Plasmid, Integron, Mobile Genetic Elements, Tf1, Saccharomyces-Cerevisiae, Schizosaccharomyces Pombe, Evolution, DNA Replication, Ty1, ty5, ty3, Ty2, ty4, Tre-5a, Science News
James A. Shapiro

A few blogs ago I asked, "Where, in fact, do 'the good ones' really come from?" By "good ones" I meant useful genome changes in evolution. This question stimulated some debate about whether it was possible to distinguish good changes from bad changes before they occur.

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