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Fission Yeast

Legitimate and Illegitimate Recombination: Targeting Homologous Exchange for Multiple Adaptive Purposes

James A. Shapiro | Posted 10.02.2012 | Science
James A. Shapiro

The molecular studies are remarkable in uncovering a striking variety of ways cells have adapted homologous recombination for diverse purposes.

Can Cells Bias Natural Genetic Engineering Toward Useful Evolutionary Outcomes?

James A. Shapiro | Posted 08.06.2012 | Science
James A. Shapiro

A few blogs ago I asked, "Where, in fact, do 'the good ones' really come from?" By "good ones" I meant useful genome changes in evolution. This question stimulated some debate about whether it was possible to distinguish good changes from bad changes before they occur.