As we have done every year since my daughter Alexandra "Alex" Scott held her very first front yard lemonade stand, volunteers across the country will host over 2,000 lemonade stands and events to raise funds for the fight against kids' cancer during National Lemonade Days.

Our gratefulness for everything that St. Jude had done for us could not be understated. That is why, when we heard that the hospital is the primary benefitting charity for the St. Jude Country Music Marathon, we felt like we had found an opportunity to give back.

It starts with us as advocates educating our physicians on these pathways and expanding the overall knowledge base of these channels. This is often difficult for a parent who is trying to balance saving their child with making every moment count.

When one couples physical fitness with a great cause, we find ourselves training harder to achieve our goals. The greater the cause, the harder the workout. I believe that there is a spark that ignites within and takes the workout and us to a higher level.

When one couples physical fitness with a great cause, we find ourselves training harder to achieve our goals. The greater the cause, the harder the workout.

Alex looked at me with a bit of a grin, but very seriously and said, "You should never give up, it's never good to give up." I have never heard a wiser or truer statement; instead of becoming frustrated and increasingly angry, Alex became increasingly more determined.

There are times in long endurance events when the destructive thoughts begin to filter through your brain, suggesting how truly pleasurable it would feel to simply take a seat and stop. As those thoughts taunted me, my mind turned to one thought: my daughter never quit, neither will I.

2012 was a transformative year in my life for several reasons, both personal and professional, and one that I feel had the potential to change the trajectory of where research against childhood cancer is headed.

For those of us who fight for greater federal funding, it is simply not acceptable to allow childhood cancer to be so poorly treated and under-recognized.

I am not trying to suggest that we should not have hope. We must have hope for a better day in the childhood cancer community. But childhood cancer remains a killer of our children, and it also remains woefully underfunded and most people are unaware of this fact.

The holiday season is a time to reflect. For me, I'm especially thankful for ongoing pediatric cancer research that enables the lives of children like Ishani to be saved.

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