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Recombination

Take 2: Why Genetic Recombination Is Not Random, and How Cells Take Advantage of Non-randomness

James A. Shapiro | Posted 10.07.2012 | Science
Read More: Natural Genetic Engineering, Antigenic Variation, Recombination, Chicken Antibody Diversification, Yeast Mating Type, Rochelle Esposito, Endonuclease, Homolgous, Cassette Exchange, Repeat Sequences, Genetic Recombination, Gene Recombination Non-Random, Genetic Recombination Non-Random, Genetic Recombination Not Random, Gene Recombination Not Random, Gene Recombination, Science News
James A. Shapiro

In the pre-DNA era, students were all taught that genetic change is random and accidental. Because the molecular details were inaccessible, this was the default assumption. But once we learned about DNA carrying hereditary information, we could research the details of how changes occur.

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Legitimate and Illegitimate Recombination: Targeting Homologous Exchange for Multiple Adaptive Purposes

James A. Shapiro | Posted 10.02.2012 | Science
Read More: Mouse Genome, Sleeping Sickness, Budding Yeast, Non-Homologous Recombination, Lyme Disease, Homologous Recombination, Recombination, Fission Yeast, Site-Specific Recombination, Rochelle Esposito, Trypanosoma Brucei, Borrelia, Science News
James A. Shapiro

The molecular studies are remarkable in uncovering a striking variety of ways cells have adapted homologous recombination for diverse purposes.

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