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Site Specific Recombination

Legitimate and Illegitimate Recombination: Targeting Homologous Exchange for Multiple Adaptive Purposes

James A. Shapiro | Posted 10.02.2012 | Science
James A. Shapiro

The molecular studies are remarkable in uncovering a striking variety of ways cells have adapted homologous recombination for diverse purposes.

DNA as Poetry: Multiple Messages in a Single Sequence

James A. Shapiro | Posted 03.25.2012 | Science
James A. Shapiro

At a time when we pride ourselves for being able to read DNA sequences with increasing speed, it is salutary to keep in mind that we are still far from knowing how to interpret the complex overlapping meanings contained in the genomic texts we store in our databases.