Success in any worthy endeavor is bumpy along the way. Go ahead. Randomly select a scientific or social wonder that we take for granted today, and chart its course to success. At some point -- probably at several points -- its developers said, in moments of weakness, "I give up," or "It's just not going to happen." Yet they soldiered on, and we are the richer for it.
No, I'm not saying you should wear a pant suit while working from your living room. But please - change out of your pajamas, will you? For me, just knowing that I look decent makes me much more likely to take my work day seriously. Unless I have a meeting where I have to look professional, my favorite wardrobe for working from home is exercise clothes. They're comfortable, presentable, and automatically give the feeling of accomplishment. It's also a motivating factor to exercise, but we'll save that for another post.
Just because you spent the entirety of your 20s focusing upon one or several of the things on your "having it all" list doesn't mean you failed. But, to gain it all, you need to reassess where you are with each item on your list. Is it time to refocus your energy from one item to another? Can you take a break from something to build up another area of your life?