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Tim Giago

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MS Is Incurable, But Science Is Getting Closer to Solving It

Posted: 06/22/10 02:35 PM ET

It contributed to the death of the black comedian, Richard Pryor. Actresses Annette Funicello, formerly of the Mickey Mouse Club and Beach Blanket movies, and Terri Garr of Young Frankenstein, have it. It is the debilitating and incurable disease known as Multiple Sclerosis, or MS.

As a part of my education about the disease I found myself in Seattle this weekend because my wife Jackie, who has MS, belongs to a group known as Teva Neuroscience, a group that holds annual forums in different parts of the United States that brings men and women with MS together to discuss the disease and talk about one of its major treatments, a medication known as Copaxone.

Among the attendees are people of nearly every race and creed, but the several forums I have attended in the past, I have never met a Native American with MS. I am certain that there are probably some out there, but as I mentioned, I have met none at the forums.

About 17 years ago most people with MS were pretty much out in the cold when it came to effective treatment. MS is a neurological illness that attacks certain areas of the brain and can cause paralysis and many of the victims of the disease are relegated to wheel chairs.

Jackie discovered she had MS when she went to her eye doctor and she later found out that many MS patients find out about the illness from their optometrists. She was on the verge of paralysis when she was brought on board for a special medical experimental program at the University of New Mexico. She was introduced to a medication given by injection known as Copaxone. For her it was literally a life saver. Not all patients can say that, but she was one that took to it. She has been on it for nearly 18 years and for her it was miraculous.

Let me say here that there was nothing dramatic about her improvement because it took place over a long period of time. It was not instantaneous. As one of the first recipients of the drug she is one of the few that has been on Copaxone from nearly the beginning. She is one of the advocates that set an example for the good things that can happen.

But not all MS patients react positively to the drug. In some there is no improvement and in others the effect is negative. But with Jackie and many others, they are able to continue living an active life, work at full-time jobs and enjoy many of the activities they enjoyed prior to contracting the illness.

For those that don't like needles, Copaxone may not be the best choice, because medication is administered by injection every day of the week. If scientists never find a pill can do the same job, the shots will be administered for the rest of patients' lives.

Ann Simpson, the director of the Teva Forum gave a speech on Saturday night and talked about the many friends she had made as the director and of the many uncomplaining, cheerful and courageous people with MS that she had come to love and respect.

I am beginning to understand how she feels. Each forum I have attended has enlightened me about the effects, good and bad, of the illness and the more I have learned, the more supportive and understanding I have become with Jackie.

If there are any Native Americans out there who have MS, or suspect they do, you can learn more about Teva Neuroscience by calling Shared Solutions at 1-800-887-8100.

No one knows what causes MS or whether there will ever be a cure for it. At the forum I heard some of the patients talk about hives as the cause, or mononucleosis or even that it is caused by vaccinations, but everyone there knows that this is all merely speculation. And as far as I know, Annette Funicello and Terri Garr are not on the Copaxone program so I do not know how they are doing.

Copyright 2010 Native Sun News

Tim Giago, an Oglala Lakota, is the publisher of Native Sun News. He was a Nieman Fellow at Harvard with the Class of 1990. His weekly column won the H. L. Mencken Award in 1985. His book, Children Left Behind, was awarded the Bronze Medal by Independent Book Publishers. Giago was inducted into the South Dakota Newspaper Hall of Fame in 2007. He can be reached at editor@nsweekly.com

 

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01:07 AM on 06/24/2010
I was one of those who did not experience success with the pharmaceuticals. I had an awful experience with avonex and discontinued immediately, copaxone was "suspected" in my "opportunistic abdominal abcess of unknown etiology" which required hospitalization to treat and steroid infusions possibly precipitated advanced pre-diabetes and some bone density loss. Sigh. I stopped all medications and sat home without hope until I learned of CCSVI. I had a balloon angioplasty in May to clear blockages in both jugulars and my azygous veins, and I experienced immediate and dramatic relief from my MS symptoms. I feel like I did before the onset of my dis-ease.
07:29 AM on 06/23/2010
Congratulations to your wife, Jackie on her success with Copaxone. I was diagnosed two years ago with MS. I am on Betaseron and my MRIs so far show no activity. As for CCSVI, clinical trials are being conducted in the US and Canada. Dr. Robert Zivadinov at SUNY Buffalo is the lead researcher in the first blinded CCSVI study in the US (Dr. Zamboni's original study was not blinded. Dr. Zivadinov discovered that although 62.4% of MS patients in his study had CCSVI (opposed to the 100% in Zamboni's study) 25.9% of the healthy controls ALSO had CCSVI, proving that CCSVI is NOT a unique condition in MS patients:

http://app.e2ma.net/campaign/31451.7eb83acea5f3d445d442bbc1ab656f55

Following up with MS patients that had balloon angioplasty done to correct their CCSVI, Dr. Zamboni reported that 47% developed restenosis):

http://www.msif.org/en/news/msif_news/ccsvi.html

Both Drs. Zivadinov and Zamboni kept their MS study subjects on their disease-modifying medications.

http://ms.about.com/b/2010/04/14/scientists-call-for-ethical-consciousness-around-ccsvi-treatment-and-research.htm

Unfortunately, there is a very vocal segment of the MS population who are calling for boycotts of the National Multiple Sclerosis Society (who have given $2.4 million towards CCSVI research) and other organizations that they feel are not receptive enough to CCSVI. Individuals who voice their doubts over CCSVI or want more studies to be done on CCSVI have been personally attacked on message boards.
12:35 AM on 06/23/2010
Why has this article omitted the biggest news in years about MS patients?

Most if not all MS patients have been proven to have venous obstructions. Most if not all of patients who have undergone treatment to correct this have had very good success rates of immediate improvement. The condition is known as CCSVI (Chronic cerebro-spinal venous insufficiency). As Wikopedia states, Chronic cerebro-spinal venous insufficiency (CCSVI) is a syndrome in which the flow of blood in the cervical and thoracic veins, from the central nervous system (CNS) to the heart, is compromised and less efficient. It is proposed that insufficient venous blood flow, in turn, promotes development of brain dysfunction, especially multiple sclerosis.

The reported blood flow compromises involve both reduced and intermittently reversed (reflux) flow velocities in the cerebral veins, changed brain capillary dynamics (altering the blood-brain barrier), and are reportedly associated with stenosis of the jugular and azygos veins. Such a vascular picture was described by Paolo Zamboni in 2008, who also reported an association of CCSVI with multiple sclerosis (MS). The hypothesis has generated optimism, especially from patients, for more effective treatment options for multiple sclerosis. It has also been received with skepticism by some in the medical community, as well as efforts by some institutions to support research into it."
10:23 PM on 06/22/2010
Why is CCSVI as a probable cause not mentioned in this piece? Why just pharma?
01:10 AM on 06/23/2010
I agree. It is truly amazing with what has been going on since Dr. Zamboni published his study on CCSVI and MS that it was not mentioned in your piece! It is a groundbreaking discovery that has helped hundreds, soon to be thousands, of people with MS all over the world!
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20091120/MS_W5_091120/20091120?s_name=W5