Naomi Watts and Sean Penn play Plame Wilson and her husband, former ambassador Joseph C. Wilson. Doug Liman, the producer behind the Bourne franchise, directed "Fair Game."
Based on Plame's 2007 memoirs "Fair Game: My Life as a Spy, My Betrayal by the White House," "Fair Game" is the only U.S. film in the running for the Palme d'Or, the festival's top prize.
The film's trailer hasn't made it online, but the clip below was posted to the festival's web site.
Plame's identity as a CIA operative was leaked to the media after her husband, a former ambassador, cast doubt on the Bush administration's claims that Saddam Hussein sought uranium in Africa.WATCH: